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Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier

The benefit of using ontologies, defined by the respective data standards, is shown. It is presented how ontologies can be used for the semantic enrichment of data and how this can contribute to the vision of the semantic web to become…

Databases · Computer Science 2009-12-16 Gerhard Mayer

Data tables in the form of spreadsheets or delimited text files are the most utilised data format in Systems Biology. However, they are often not sufficiently structured and lack clear naming conventions that would be required for…

Molecular Networks · Quantitative Biology 2015-09-30 Wolfram Liebermeister , Timo Lubitz , Jens Hahn

Data management, which encompasses activities and strategies related to the storage, organization, and description of data and other research materials, helps ensure the usability of datasets -- both for the original research team and for…

Digital Libraries · Computer Science 2022-04-14 John A. Borghi , Ana E. Van Gulick

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

Databases · Computer Science 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources. Such…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Jia Yu , Rajkumar Buyya

This document explores the advantages of integrating open source software and practices in managing a scientific lab, emphasizing reproducibility and the avoidance of pitfalls. It details practical applications from website management using…

Computers and Society · Computer Science 2024-05-14 Julien Cohen-Adad

The term scientific workflow has evolved over the last two decades to encompass a broad range of compositions of interdependent compute tasks and data movements. It has also become an umbrella term for processing in modern scientific…

Modern tools for biological research, especially microscopy, have rapidly advanced in recent years, which has led to the generation of increasingly large amounts of data on a regular basis. The result is that scientists desperately need…

Other Quantitative Biology · Quantitative Biology 2021-08-18 Andrey Andreev , Tom Morrell , Kristin Briney , Sandra Gesing , Uri Manor

Biologists are increasingly using databases for storing and managing their data. Biological databases typically consist of a mixture of raw data, metadata, sequences, annotations, and related data obtained from various sources. Current…

Databases · Computer Science 2007-05-23 Mohamed Y. Eltabakh , Mourad Ouzzani , Walid G. Aref

Workflow technology is rapidly evolving and, rather than being limited to modeling the control flow in business processes, is becoming a key mechanism to perform advanced data management, such as big data analytics. This survey focuses on…

Databases · Computer Science 2017-01-27 Georgia Kougka , Anastasios Gounaris , Alkis Simitsis

Scientific workflows are powerful tools for management of scalable experiments, often composed of complex tasks running on distributed resources. Existing cyberinfrastructure provides components that can be utilized within repeatable…

Computers and Society · Computer Science 2019-03-05 Ilkay Altintas , Shweta Purawat , Daniel Crawl , Alok Singh , Kyle Marcus

In recent years, Large Language Models (LLMs) have emerged as transformative tools across numerous domains, impacting how professionals approach complex analytical tasks. This systematic mapping study comprehensively examines the…

Computers and Society · Computer Science 2025-08-19 Sai Sanjna Chintakunta , Nathalia Nascimento , Everton Guimaraes

Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-08 Alessandro Margara , Gianpaolo Cugola , Nicolò Felicioni , Stefano Cilloni

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

Today's software systems like cyber-physical production systems or big data systems have to process large volumes and diverse types of data which heavily influences the quality of these so-called data-intensive systems. However, traditional…

Software Engineering · Computer Science 2019-04-10 Michael Felderer , Barbara Russo , Florian Auer

Up-to-date meta-databases are vital for the analysis of biological data. However,the current exponential increase in biological data leads to exponentially increasing meta-database sizes. Large-scale meta-database management is therefore an…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-01-31 Edvard Pedersen , Lars Ailo Bongo

This paper tries to reduce the effort of learning, deploying, and integrating several frameworks for the development of e-Science applications that combine simulations with High-Performance Data Analytics (HPDA). We propose a way to extend…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-10 Cristian Ramon-Cortes , Francesc Lordan , Jorge Ejarque , Rosa M. Badia
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