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Bad statistics make research papers unreproducible and misleading. For the most part, the reasons for such misusage of numerical data have been found and addressed years ago by experts and proper practical solutions have been presented…

Other Statistics · Statistics 2020-10-26 Farzan Shenavarmasouleh , Hamid R. Arabnia

Null hypothesis statistical significance tests (NHST) are widely used in quantitative research in the empirical sciences including scientometrics. Nevertheless, since their introduction nearly a century ago significance tests have been…

Other Statistics · Statistics 2014-02-06 Jesper W. Schneider

Phase III randomized clinical trials play a monumentally critical role in the evaluation of new medical products. Because of the intrinsic nature of uncertainty embedded in our capability in assessing the efficacy of a medical product,…

Methodology · Statistics 2019-02-25 Changyu Shen , Xiaochun Li

This paper presents some ideas and results of using uncertainty management methods in the presence of data in preference to other statistical and machine learning methods. A medical domain is used as a test-bed with data available from a…

Artificial Intelligence · Computer Science 2013-04-08 Mary McLeish , P. Yao , M. Cecile , T. Stirtzinger

How should we evaluate the effect of a policy on the likelihood of an undesirable event, such as conflict? The significance test has three limitations. First, relying on statistical significance misses the fact that uncertainty is a…

Methodology · Statistics 2022-05-03 Akisato Suzuki

Matched case-control studies are commonly employed in epidemiological research for their convenience and efficiency. Analysis of secondary outcomes can yield valuable insights into biological pathways and help identify genetic variants of…

Methodology · Statistics 2026-02-24 Shanshan Liu , Guoqing Diao

We discuss problems the null hypothesis significance testing (NHST) paradigm poses for replication and more broadly in the biomedical and social sciences as well as how these problems remain unresolved by proposals involving modified…

Methodology · Statistics 2021-07-21 Blakeley B. McShane , David Gal , Andrew Gelman , Christian Robert , Jennifer L. Tackett

We examine the role of trustworthiness and trust in statistical inference, arguing that it is the extent of trustworthiness in inferential statistical tools which enables trust in the conclusions. Certain tools, such as the p-value and…

Methodology · Statistics 2021-05-11 David J. Hand

Frequentist statistical methods, such as hypothesis testing, are standard practice in papers that provide benchmark comparisons. Unfortunately, these methods have often been misused, e.g., without testing for their statistical test…

Methodology · Statistics 2021-05-18 David Issa Mattos , Jan Bosch , Helena Holmström Olsson

Research often necessitates of samples, yet obtaining large enough samples is not always possible. When it is, the researcher may use one of two methods for deciding upon the required sample size: rules-of-thumb, quick yet uncertain, and…

Methodology · Statistics 2016-04-08 Jose D. Perezgonzalez

A popular approach to significance testing proposes to decide whether the given hypothesized statistical model is likely to be true (or false). Statistical decision theory provides a basis for this approach by requiring every significance…

Methodology · Statistics 2013-01-08 William Perkins , Mark Tygert , Rachel Ward

Simulations are valuable tools for empirically evaluating the properties of statistical methods and are primarily employed in methodological research to draw general conclusions about methods. In addition, they can often be useful to…

Other Statistics · Statistics 2025-10-08 Anne-Laure Boulesteix , Patrick Callahan , Luzia Hanssum , Vincent Gaertner , Eva Hoster

In this paper we describe the usefulness of statistical validation techniques for human factors survey research. We need to investigate a diversity of validity aspects when creating metrics in human factors research, and we argue that the…

Software Engineering · Computer Science 2019-04-05 Lucas Gren , Alfredo Goldman

The experimental evaluation of the methods and concepts covered in software engineering has been increasingly valued. This value indicates the constant search for new forms of assessment and validation of the results obtained in Software…

Software Engineering · Computer Science 2020-06-30 T. F. M. Sirqueira , M. A. Miguel , H. L. O. Dalpra , M. A. P. Araujo , J. M. N. David

Many practical studies rely on hypothesis testing procedures applied to data sets with missing information. An important part of the analysis is to determine the impact of the missing data on the performance of the test, and this can be…

Methodology · Statistics 2011-02-15 Dan L. Nicolae , Xiao-Li Meng , Augustine Kong

Every scientific endeavour consists of (at least) two components: A hypothesis on the one hand and data on the other. There is always a more or less abstract level - some theory, a set of concepts, certain relations of ideas - and a…

Applications · Statistics 2018-01-08 Uwe Saint-Mont

Statistical practice does not automatically follow methodological innovation. Regularization methods, widely advocated to reduce overfitting and stabilize inference, are readily available in modern software, but are not consistently used by…

We analyze different types of simulations that applied researchers can use to assess whether their inference methods reliably control false-positive rates. We show that different assessments involve trade-offs, varying in the types of…

Econometrics · Economics 2025-10-03 Bruno Ferman

Simulation studies are commonly used in methodological research for the empirical evaluation of data analysis methods. They generate artificial data sets under specified mechanisms and compare the performance of methods across conditions.…

Methodology · Statistics 2025-07-11 Samuel Pawel , František Bartoš , Björn S. Siepe , Anna Lohmann

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

Methodology · Statistics 2013-06-26 Jonathan Rosenblatt