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A model of the columnar functional organization of neocortical association areas is studied. The neuronal network is composed of many Hebbian autoassociators, or modules, each of which interacts with a relatively small number of the others.…

Disordered Systems and Neural Networks · Physics 2020-05-14 Carlo Fulvi Mari

Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal dentate gyrus (DG). In comparison to mature GCs (mGCs) (born during development), the imGCs exhibit two competing distinct properties such as high…

Neurons and Cognition · Quantitative Biology 2023-01-16 Sang-Yoon Kim , Woochang Lim

The evolutionary fitness landscape of biological molecules is extremely sparse and heterogeneous, with functional sequences forming isolated dense ``islands'' within a vast combinatorial space of largely non-functional variants. Protein…

We investigate disynaptic effect of the hilar cells on pattern separation in a spiking neural network of the hippocampal dentate gyrus (DG). The principal granule cells (GCs) in the DG perform pattern separation, transforming similar input…

Neurons and Cognition · Quantitative Biology 2021-09-28 Sang-Yoon Kim , Woochang Lim

Continuous attractor networks (CANs) are widely used to model how the brain temporarily retains continuous behavioural variables via persistent recurrent activity, such as an animal's position in an environment. However, this memory…

Neural and Evolutionary Computing · Computer Science 2025-07-02 Madison Cotteret , Christopher J. Kymn , Hugh Greatorex , Martin Ziegler , Elisabetta Chicca , Friedrich T. Sommer

Mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal…

Neurons and Cognition · Quantitative Biology 2016-01-19 Kentaro Hoffman , Andrey Babichev , Yuri Dabaghian

The grid cells (GCs) of the medial entorhinal cortex (MEC) and place cells (PCs) of the hippocampus are key elements of the brain network for the metric representation of space. Currently, any of the existing theoretical models can explain…

Neurons and Cognition · Quantitative Biology 2015-07-01 Andrey Stepanyuk

Dense Associative Memories or modern Hopfield networks permit storage and reliable retrieval of an exponentially large (in the dimension of feature space) number of memories. At the same time, their naive implementation is non-biological,…

Neurons and Cognition · Quantitative Biology 2021-04-29 Dmitry Krotov , John Hopfield

The human brain possesses the extraordinary capability to contextualize the information it receives from our environment. The entorhinal-hippocampal plays a critical role in this function, as it is deeply engaged in memory processing and…

Artificial Intelligence · Computer Science 2023-07-06 Paul Stoewer , Achim Schilling , Andreas Maier , Patrick Krauss

Autoassociative networks were proposed in the 80's as simplified models of memory function in the brain, using recurrent connectivity with hebbian plasticity to store patterns of neural activity that can be later recalled. This type of…

Disordered Systems and Neural Networks · Physics 2011-11-10 Emilio Kropff , Alessandro Treves

Open-vocabulary 3D scene understanding is crucial for applications requiring natural language-driven spatial interpretation, such as robotics and augmented reality. While 3D Gaussian Splatting (3DGS) offers a powerful representation for…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Wei Sun , Yanzhao Zhou , Jianbin Jiao , Yuan Li

The standard model of memory consolidation foresees that memories are initially recorded in the hippocampus, while features that capture higher-level generalisations of data are created in the cortex, where they are stored for a possibly…

Neurons and Cognition · Quantitative Biology 2017-06-20 Alessandro Fontana

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

Machine Learning · Computer Science 2025-09-03 Lucie Fontaine , Frédéric Alexandre

Krotov and Hopfield (2021) proposed a biologically plausible two-layer associative memory network with memory storage capacity exponential in the number of visible neurons. However, the capacity was only linear in the number of hidden…

Neurons and Cognition · Quantitative Biology 2026-03-11 Mohadeseh Shafiei Kafraj , Dmitry Krotov , Peter E. Latham

The standard consolidation theory states that short-term memories located in the hippocampus enable the consolidation of long-term memories in the neocortex. In other words, the neocortex slowly learns long-term memories with a transient…

Neurons and Cognition · Quantitative Biology 2024-04-05 Lisa Blum Moyse , Hugues Berry

The spatial distribution of the gaseous components of the Milky Way is of great importance for a number of different fields, for example, Galactic structure, star formation, and cosmic rays. However, obtaining distance information to…

Analyzing the brain in terms of organizational structures at intermediate scales provides an approach to negotiate the complexity arising from interactions between its large number of components. Focusing on a wiring diagram that spans the…

Neurons and Cognition · Quantitative Biology 2023-01-10 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

The brain has computational capabilities that surpass those of modern systems, being able to solve complex problems efficiently in a simple way. Neuromorphic engineering aims to mimic biology in order to develop new systems capable of…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno

Functional 3D scene graphs offer a versatile and flexible representation for 3D scene understanding and robotic manipulation, defined by object nodes, interactive elements, and functional relationship edges. However, their potential remains…

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations, emphasizing significant…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Jiawen Li , Yuxuan Chen , Hongbo Chu , Qiehe Sun , Tian Guan , Anjia Han , Yonghong He