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We study, numerically and analytically, the forced transport of deformable containers through a narrow constriction. Our central aim is to quantify the competition between the constriction geometry and the active forcing, regulating whether…

Soft Condensed Matter · Physics 2015-02-10 Remy Kusters , Thijs van der Heijden , Badr Kaoui , Jens Harting , Cornelis Storm

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky

Molecular machines described in this paper are meant to be such molecular systems that make use of conformational mobility (i.e. hindered rotation around chemical bonds and molecular construction deformations with formation and breakage of…

Chemical Physics · Physics 2007-05-23 Ye. V. Tourleigh , K. V. Shaitan

The effect of curvature and how it induces and enhances the transport of colloidal particles driven through narrow channels represent an unexplored research avenue. Here we combine experiments and simulations to investigate the dynamics of…

Via computer simulations of the standard binary Lennard-Jones glass former we have obtained in a systematic way a large set of close-by pairs of minima on the potential energy landscape, i.e. double-well potentials (DWP). We analyze this…

Materials Science · Physics 2009-11-10 J. Reinisch , A. Heuer

Nuclear pore complexes are constantly confronted by large fluxes of macromolecules and macromolecular complexes that need to get into and out of the nucleus. Such bi-directional traffic occurring in a narrow channel can easily lead to…

Biological Physics · Physics 2008-07-22 Ruti Kapon , Alon Topchik , David Mukamel , and Ziv Reich

Inside cells, cargos such as vesicles and organelles are transported by molecular motors to their correct locations via active motion on cytoskeletal tracks and passive, Brownian diffusion. During the transportation of cargos, motor-cargo…

Soft Condensed Matter · Physics 2018-04-10 Supravat Dey , Kevin Ching , Moumita Das

We have studied the flow properties of vortices driven through easy flow mesoscopic channels by means of the mode locking (ML) technique. We observe a ML jump with large voltage broadening in the real part of the rf-impedance. Upon…

Superconductivity · Physics 2009-11-10 N Kokubo , R. Besseling , P. H. Kes

This paper addresses the question of whether a ``rigid molecule'' (one which does not deform in an external field) used as the conducting channel in a standard three-terminal MOSFET configuration can offer any performance advantage relative…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 Prashant Damle , Titash Rakshit , Magnus Paulsson , Supriyo Datta

Conduction of electrons in matter is ultimately described by quantum mechanics. Yet at low frequency or long time scales, low temperature quantum transport is perfectly described by this very simple idea: electrons are emitted by the…

Mesoscale and Nanoscale Physics · Physics 2015-06-17 Karl Thibault , Julien Gabelli , Christian Lupien , Bertrand Reulet

Systems under external confinement and constraints often show interesting properties. In this thesis, we study some systems under external confinement. We begin by finding out the probability distribution of end-to-end separation of a Worm…

Soft Condensed Matter · Physics 2007-05-23 Debasish Chaudhuri

We have investigated by molecular dynamics method the influence of a finite number of particles used in computer simulations on fluctuations of thermodynamic properties. As a case study, we used the two-dimensional Lennard-Jones system. 2D…

Statistical Mechanics · Physics 2024-03-05 M. V. Kondrin , Y. B. Lebed

We study biased, diffusive transport of Brownian particles through narrow, spatially periodic structures in which the motion is constrained in lateral directions. The problem is analyzed under the perspective of the Fick-Jacobs equation…

Statistical Mechanics · Physics 2007-07-10 P. S. Burada , G. Schmid , D. Reguera , J. M. Rubi , P. Hanggi

The traffic of molecular motors which interact through mutual exclusion is studied theoretically for half-open tube-like compartments. These half-open tubes mimic the shapes of axons. The mutual exclusion leads to traffic jams or density…

Statistical Mechanics · Physics 2007-05-23 Melanie J. I. Muller , Stefan Klumpp , Reinhard Lipowsky

We scrutinize the temporally-resolved speed of active cargo transport in living cells, and show intermittent bursting motions. These nonlinear fluctuations follow a scaling law over several decades of time and space, the statistical…

Subcellular Processes · Quantitative Biology 2015-06-16 Bo Wang , James Kuo , Steve Granick

Measurements of the thermal conductance of single-molecule junctions have recently been reported for the first time. It is presently unclear, how much the heat transport can be controlled through molecule-internal effects. The search for…

Mesoscale and Nanoscale Physics · Physics 2025-10-01 Matthias Blaschke , Fabian Pauly

Simulating percolation and critical phenomena of labelled species inside films composed of single-component linear homogeneous macromolecules using molecular Monte Carlo method in 3 dimensions, we study dependence of these conducting…

Soft Condensed Matter · Physics 2019-09-05 Yuki Norizoe , Hiroshi Morita

We investigate a driven two-channel system where particles on different lanes mutually obstruct each others motion extending an earlier model by Popkov and Peschel [1]. This obstruction may occur in biological contexts due to steric…

Biological Physics · Physics 2015-03-13 Anna Melbinger , Tobias Reichenbach , Thomas Franosch , Erwin Frey

The force distribution of a tagged atom in a Lennard-Jones fluid in the canonical ensemble is studied with a focus on its dependence on inherent physical parameters: number density ($n$) and temperature ($T$). Utilising structural…

Soft Condensed Matter · Physics 2022-03-14 Jonathan Utterson , Radek Erban

Particle-laden turbulent flow that separates due to a bump inside a channel is simulated to analyse the effects of the Stokes number and the lift force on the particle spatial distribution. The fluid friction Reynolds number is…