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A methodology is developed for data analysis based on empirically constructed geodesic metric spaces. For a probability distribution, the length along a path between two points can be defined as the amount of probability mass accumulated…

Statistics Theory · Mathematics 2019-03-18 Kei Kobayashi , Henry P. Wynn

The path-difference metric is one of the oldest and most popular distances for the comparison of phylogenetic trees, but its statistical properties are still quite unknown. In this paper we compute the expected value under the Yule model of…

Populations and Evolution · Quantitative Biology 2012-03-13 Gabriel Cardona , Arnau Mir , Francesc Rossello

In this article, we propose tree edit distance with variables, which is an extension of the tree edit distance to handle trees with variables and has a potential application to measuring the similarity between mathematical formulas,…

Data Structures and Algorithms · Computer Science 2021-05-12 Tatsuya Akutsu , Tomoya Mori , Naotoshi Nakamura , Satoshi Kozawa , Yuhei Ueno , Thomas N. Sato

We introduce new distance measures for comparing straight-line embedded graphs based on the Fr\'echet distance and the weak Fr\'echet distance. These graph distances are defined using continuous mappings and thus take the combinatorial…

Computational Geometry · Computer Science 2019-09-12 Hugo A. Akitaya , Maike Buchin , Bernhard Kilgus , Stef Sijben , Carola Wenk

We introduce a new phylogenetic reconstruction algorithm which, unlike most previous rigorous inference techniques, does not rely on assumptions regarding the branch lengths or the depth of the tree. The algorithm returns a forest which is…

Populations and Evolution · Quantitative Biology 2011-09-30 Constantinos Daskalakis , Elchanan Mossel , Sebastien Roch

We present a new class of metrics for unrooted phylogenetic $X$-trees derived from the Gromov-Hausdorff distance for (compact) metric spaces. These metrics can be efficiently computed by linear or quadratic programming. They are robust…

Metric Geometry · Mathematics 2015-04-23 Volkmar Liebscher

The goal of this paper is to study the similarity between sequences using a distance between the \emph{context} trees associated to the sequences. These trees are defined in the framework of \emph{Sparse Probabilistic Suffix Trees} (SPST),…

Applications · Statistics 2008-04-29 Florencia Leonardi , Sergio R. Matioli , Hugo A. Armelin , Antonio Galves

In evolutionary biology, phylogenetic networks are constructed to represent the evolution of species in which reticulate events are thought to have occurred, such as recombination and hybridization. It is therefore useful to have…

Populations and Evolution · Quantitative Biology 2017-03-16 Vincent Moulton , James Oldman , Taoyang Wu

The problem of comparing trees representing the evolutionary histories of cancerous tumors has turned out to be crucial, since there is a variety of different methods which typically infer multiple possible trees. A departure from the…

Data Structures and Algorithms · Computer Science 2019-04-03 Giulia Bernardini , Paola Bonizzoni , Gianluca Della Vedova , Murray Patterson

Phylogenetic tree comparison metrics are an important tool in the study of evolution, and hence the definition of such metrics is an interesting problem in phylogenetics. In a paper in Taxon fifty years ago, Sokal and Rohlf proposed to…

Populations and Evolution · Quantitative Biology 2013-01-22 Gabriel Cardona , Arnau Mir , Francesc Rossello , Lucia Rotger , David Sanchez

We study the geodesic complexity of the ordered and unordered configuration spaces of graphs in both the $\ell_1$ and $\ell_2$ metrics. We determine the geodesic complexity of the ordered two-point $\varepsilon$-configuration space of any…

Geometric Topology · Mathematics 2022-08-10 Donald M. Davis , Michael Harrison , David Recio-Mitter

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

A central theme in phylogenetics is the reconstruction and analysis of evolutionary trees from a given set of data. To determine the optimal search methods for reconstructing trees, it is crucial to understand the size and structure of the…

Populations and Evolution · Quantitative Biology 2016-08-15 Jamie V. de Jong , Jeanette C McLeod , Mike Steel

The Neighbor-Joining algorithm is a popular distance-based phylogenetic method that computes a tree metric from a dissimilarity map arising from biological data. Realizing dissimilarity maps as points in Euclidean space, the algorithm…

Combinatorics · Mathematics 2020-09-18 Ruth Davidson , Abraham Martin del Campo

Tree reconstruction methods are often judged by their accuracy, measured by how close they get to the true tree. Yet most reconstruction methods like ML do not explicitly maximize this accuracy. To address this problem, we propose a…

Populations and Evolution · Quantitative Biology 2009-11-22 Peter Huggins , Wenbin Li , David Haws , Thomas Friedrich , Jinze Liu , Ruriko Yoshida

This paper give a simple linear-time algorithm that, given a weighted digraph, finds a spanning tree that simultaneously approximates a shortest-path tree and a minimum spanning tree. The algorithm provides a continuous trade-off: given the…

Data Structures and Algorithms · Computer Science 2015-06-02 Samir Khuller , Balaji Raghavachari , Neal E. Young

An added edge to a graph is called an inset edge. Predicting k inset edges which minimize the average distance of a graph is known to be NP-Hard. However, when k = 1 the complexity of the problem is polynomial. In this paper, some tools for…

Computational Complexity · Computer Science 2020-08-14 M. H. Khalifeh , A. -H. Esfahanian

Several important algorithms for machine learning and data analysis use pairwise distances as input. On Riemannian manifolds these distances may be prohibitively costly to compute, in particular for large datasets. To tackle this problem,…

Differential Geometry · Mathematics 2019-04-29 Philipp Harms , Elodie Maignant , Stefan Schlager

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

The Fr\'echet distance is a popular similarity measure that is well-understood for polygonal curves in $\mathbb{R}^d$: near-quadratic time algorithms exist, and conditional lower bounds suggest that these results cannot be improved…

Computational Geometry · Computer Science 2025-05-09 Thijs van der Horst , Marc van Kreveld , Tim Ophelders , Bettina Speckmann