Related papers: Modelling radiation-induced cell cycle delays
Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner. Cell synchronization techniques have been generally employed to…
Cell size is a fundamental determinant of cellular physiology, influencing processes such as growth, division, and function. In this study, we develop a segmented mathematical framework to investigate how different control mechanisms…
Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…
Cell polarization and directional cell migration can display random, persistent and oscillatory dynamic patterns. However, it is not clear if these polarity patterns can be explained by the same underlying regulatory mechanism. Here, we…
A multi-timescale hybrid model is proposed to study microscopically the degraded performance of electronic devices, covering three individual stages of radiation effects studies, including ultrafast displacement cascade, intermediate defect…
Large-scale tissue deformation during biological processes such as morphogenesis requires cellular rearrangements. The simplest rearrangement in confluent cellular monolayers involves neighbor exchanges among four cells, called a T1…
Exploiting the information provided by the molecular noise of a biological process has proven to be valuable in extracting knowledge about the underlying kinetic parameters and sources of variability from single cell measurements. However,…
Purpose: Cell size is a fundamental characteristic of all tissues, and changes in cell size in cancer reflect tumor status and response to treatments, such as apoptosis and cell cycle arrest. Unfortunately, cell size can only be obtained by…
Ionization is critical in the formation and evolution of plasma dynamics; collisional ionization, in particular, is an often overlooked source of electrons when dealing with laser-plasma interactions. Ionization plays a crucial role in…
Context: Low-frequency radio observations are heavily impacted by the ionosphere, where dispersive delays can outpace even instrumental clock offsets, posing a serious calibration challenge. Especially below 100 MHz, phase unwrapping…
In real-world systems, phase transitions often materialize abruptly, making it difficult to design appropriate controls that help uncover underlying processes. Some agent-based computational models display transformations similar to phase…
When traveling in the heliosphere, Galactic cosmic rays (GCRs) are subjected to the solar modulation effect, a quasiperiodical change of their intensity caused by the 11-year cycle of solar activity. Here we investigate the association of…
This paper reviews the new highly interdisciplinary research field studying the behavior of condensed matter systems exposed to radiation. The paper highlights several relevant examples of recent advances in the field and provides a roadmap…
We first address the problem of initiation behind decaying shock waves analytically and numerically. The ignition along a particle path crossing the shock is analysed in terms of its volumetric expansion, evaluated as a function of the…
Laser spectroscopic studies on minute samples of exotic radioactive nuclei require very efficient experimental techniques. In addition, high resolving powers are required to allow extraction of nu- clear structure information. Here we…
We simulate scattering delays from the interstellar medium to examine the effectiveness of three estimators in recovering these delays in pulsar timing data. Two of these estimators use the more traditional process of fitting…
When entering the heliosphere, Galactic cosmic rays (GCRs) are influenced by magnetic turbulence and Solar wind disturbances, which cause the so-called "solar modulation" effect. Understanding the time-dependent relationship between the…
The main purpose of this paper is to provide a summary of the fundamental methods for analyzing delay differential equations arising in biology and medicine. These methods are employed to illustrate the effects of time delay on the behavior…
The scientific community shows a great interest in the study of DNA damage induction, DNA damage repair and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in-silico methods have been…
Monitoring the health of lithium-ion batteries' internal components as they age is crucial for optimizing cell design and usage control strategies. However, quantifying component-level degradation typically involves aging many cells and…