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Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes. While research into the diagnostic potential and general medical relevance of these trace…

Isoprene is one of the most abundant endogenous volatile organic compounds (VOCs) contained in human breath and is considered to be a potentially useful biomarker for diagnostic and monitoring purposes. However, neither the exact…

Quantitative Methods · Quantitative Biology 2015-03-18 Helin Koc , Julian King , Gerald Teschl , Karl Unterkofler , Susanne Teschl , Pawel Mochalski , Hartmann Hinterhuber , Anton Amann

Breath acetone represents a promising non-invasive biomarker for monitoring fat oxidation during exercise. However, its utility is limited by confounding factors, as well as by the fact that significant changes in concentration occur only…

Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These…

Quantitative Methods · Quantitative Biology 2015-03-13 Julian King , Karl Unterkofler , Gerald Teschl , Susanne Teschl , Helin Koc , Hartmann Hinterhuber , Anton Amann

Isothermal rebreathing has been proposed as an experimental technique for estimating the alveolar levels of hydrophilic volatile organic compounds (VOCs) in exhaled breath. Using the prototypic test compound acetone we demonstrate that the…

Quantitative Methods · Quantitative Biology 2012-12-11 Julian King , Karl Unterkofler , Gerald Teschl , Susanne Teschl , Pawel Mochalski , Helin Koc , Hartmann Hinterhuber , Anton Amann

We develop a simple three compartment model based on mass balance equations which quantitatively describes the dynamics of breath methane concentration profiles during exercise on an ergometer. With the help of this model it is possible to…

In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of…

Quantitative Methods · Quantitative Biology 2015-06-26 Karl Unterkofler , Julian King , Pawel Mochalski , Martin Jandacka , Helin Koc , Susanne Teschl , Anton Amann , Gerald Teschl

A pilot study of exhaled volatile compounds and their correlation with blood glucose levels in eight children with type 1 diabetes is reported. Five paired blood and breath samples were obtained from each child over a 6 hour period. The…

Medical Physics · Physics 2013-03-19 S Stevens , C Garner , C Wei , R Greenwood , J Hamilton-Shield , B de Lacy Costello , N Ratcliffe , C Probert

We have developed a method to quantify reaction product ratios using high resolution microwave spectroscopy in a cryogenic buffer gas cell. We demonstrate the power of this method with the study of the ozonolysis of isoprene,…

Chemical Physics · Physics 2018-09-11 Jessica P. Porterfield , Sandra Eibenberger , Dave Patterson , Michael C. McCarthy

To date, researchers have identified over 1000 different compounds contained in human breath. These molecules have both endogenous and exogenous origins and provide information about physiological processes occurring in the body as well as…

Breathing rate (BR), minute ventilation (VE), and other respiratory parameters are essential for real-time patient monitoring in many acute health conditions, such as asthma. The clinical standard for measuring respiration, namely…

Signal Processing · Electrical Eng. & Systems 2020-11-26 Ridwan Alam , David B. Peden , John C. Lach

Research for possible biosignature gases on habitable exoplanet atmosphere is accelerating. We add isoprene, C5H8, to the roster of biosignature gases. We found that formation of isoprene geochemical formation is highly thermodynamically…

Earth and Planetary Astrophysics · Physics 2021-04-09 Zhuchang Zhan , Sara Seager , Janusz Jurand Petkowski , Clara Sousa-Silva , Sukrit Ranjan , Jingcheng Huang , William Bains

The testing of atmosphere-breathing electric propulsion intakes is an important step in the development of functional propulsion systems which provide sustained drag compensation in very low Earth orbits. To make satellite operations more…

In the last few decades, several wearable devices have been designed to monitor respiration rate in an effort to capture pulmonary signals with higher accuracy and reduce patients' discomfort during use. In this article, we present the…

Signal Processing · Electrical Eng. & Systems 2024-12-10 Bardia Baraeinejad , Maryam Forouzesh , Saba Babaei , Yasin Naghshbandi , Yasaman Torabi , Shabnam Fazliani

Monitoring respiration parameters such as respiratory rate could be beneficial to understand the impact of training on equine health and performance and ultimately improve equine welfare. In this work, we compare deep learning-based methods…

Signal Processing · Electrical Eng. & Systems 2025-08-05 Jeanne I. M. Parmentier , Rhana M. Aarts , Elin Hernlund , Marie Rhodin , Berend Jan van der Zwaag

Purpose Infectious agents, such as SARS-CoV-2, can be carried by droplets expelled during breathing. The spatial dissemination of droplets varies according to their initial velocity. After a short literature review, our goal was to…

Quantitative Methods · Quantitative Biology 2021-01-12 Antoine Giovanni , Thomas Radulesco , Gilles Bouchet , Alexia Mattei , Joana Révis , Estelle Bogdanski , Justin Michel

Oxygen consumption (VO$_2$) provides established clinical and physiological indicators of cardiorespiratory function and exercise capacity. However, VO$_2$ monitoring is largely limited to specialized laboratory settings, making its…

Machine Learning · Computer Science 2021-10-14 Robert Amelard , Eric T Hedge , Richard L Hughson

Purpose: Pencil beam scanning proton therapy is sensitive to respiratory motion, leading to potential dose inhomogeneities due to interplay effects. We developed and validated a predictive framework to assess interplay and motion robustness…

The analysis of trail-running performance appears to be complex and cardio-respiratory and muscular factors could have a variable importance depending on the inclination. Our study aims to determine the role of these parameters in…

Tissues and Organs · Quantitative Biology 2023-12-20 Corentin Hingrand , Adrien Combes , Nicolas Olivier , Samir Bensaid , Frédéric Daussin

Results of an experiment are presented whose aim is to explore the relationship between respiration and cerebral oxygenation. Measurements of end tidal CO2 (EtCO2) were taken simultaneously with cerebral oxygen saturation (rSO2) using the…

Medical Physics · Physics 2011-03-30 Alexander Gersten , Dov Heimer , Amir Raz
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