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The eukaryotic flagellum beats periodically, driven by the oscillatory dynamics of molecular motors, to propel cells and pump fluids. Small, but perceivable fluctuations in the beat of individual flagella have physiological implications for…

Cell Behavior · Quantitative Biology 2015-06-18 Rui Ma , Gary S. Klindt , Ingmar H. Riedel-Kruse , Frank Jülicher , Benjamin M. Friedrich

In biological tissues, it is now well-understood that mechanical cues are a powerful mechanism for pattern regulation. While much work has focused on interactions between cells and external substrates, recent experiments suggest that cell…

Soft Condensed Matter · Physics 2017-11-01 Michael Czajkowski , Dapeng Bi , M. Lisa Manning , M. Cristina Marchetti

Spermatozoa self-propel by propagating bending waves along a predominantly active elastic flagellum. The organized structure of the "9 + 2" axoneme is lost in the most-distal few microns of the flagellum, and therefore this region is…

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

Many microorganisms live and evolve in complex fluids. Examples include mammalian spermatozoa in cervical mucus, worms (e.g., \textit{C. elegans}) in wet soil, and bacteria (e.g., \textit{H. pylori}) in our stomach lining. Due to the…

Fluid Dynamics · Physics 2022-10-21 Paulo E. Arratia

Active matter exhibits various forms of non-equilibrium states in the absence of external forcing, including macroscopic steady-state currents. Such states are often too complex to be modelled from first principles and our understanding of…

Soft Condensed Matter · Physics 2020-09-17 Viktor Škultéty , Cesare Nardini , Joakim Stenhammar , Davide Marenduzzo , Alexander Morozov

We use a three-bead-spring model to investigate the dynamics of bi-flagellate micro-swimmers near a surface. While the primary dynamics and scattering are governed by geometric-dependent direct contact, the fluid flows generated by the…

Biological Physics · Physics 2017-08-17 Enkeleida Lushi , Vasily Kantsler , Raymond E. Goldstein

We study the stochastic hydrodynamics of colonies of flagellated swimming cells, typified by multicellular choanoflagellates, which can form both rosette and chainlike shapes. The objective is to link cell-scale dynamics to colony-scale…

Quantitative Methods · Quantitative Biology 2023-07-21 Yonatan Ashenafi , Peter R. Kramer

Many self-propelled microorganisms are attracted to surfaces. This makes their dynamics in restricted geometries very different from that observed in the bulk. Swimming along walls is beneficial for directing and sorting cells, but may be…

Synchronization plays a crucial role in the dynamics of living organisms, from fireflies flashing in unison to pacemaker cells that jointly generate heartbeats. Uncovering the mechanism behind these phenomena requires an understanding of…

Adaptation and Self-Organizing Systems · Physics 2024-05-16 Aleksandre Japaridze , Victor Struijk , Kushal Swamy , Irek Roslon , Oriel Shoshani , Cees Dekker , Farbod Alijani

We consider a suspension of active rigid particles (swimmers) in a steady Stokes flow, where particles are distributed according to a stationary ergodic random process, and we study its homogenization in the macroscopic limit. A key point…

Analysis of PDEs · Mathematics 2023-03-15 Armand Bernou , Mitia Duerinckx , Antoine Gloria

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

Fluid Dynamics · Physics 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

Bioclogging, the clogging of pores with living particles, is a complex process that involves various coupled mechanisms such as hydrodynamics and particle properties. This article explores bioclogging at the microscale level. At this scale,…

Low Reynolds number direct simulations of large populations of hydrodynamically interacting swimming particles confined between planar walls are performed. The results of simulations are compared with a theory that describes dilute…

Fluid Dynamics · Physics 2015-05-13 Juan P. Hernandez-Ortiz , Patrick T. Underhill , Michael D. Graham

We calculate the hydrodynamic flow field generated far from a cilium which is attached to a surface and beats periodically. In the case of two beating cilia, hydrodynamic interactions can lead to synchronization of the cilia, which are…

Biological Physics · Physics 2007-05-23 Andrej Vilfan , Frank Julicher

We study here the curious particle dynamics resulting from electro-osmotic flow around a microchannel junction corner whose dielectric walls are weakly polarizable. The hydrodynamic velocity field is obtained via superposition of a linear…

Fluid Dynamics · Physics 2015-06-19 Matan Zehavi , Gilad Yossifon

We consider a phase-separating mixture of active and passive fluids and explore morphological asymmetries of the emerging dominantly bicontinous dynamic emulsion. Two-dimensional numerical simulations reveal that the geometric and…

Soft Condensed Matter · Physics 2026-01-22 Rainer Backofen , Axel Voigt

Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukarytic flagellated microswimmers in linear viscosity…

Soft Condensed Matter · Physics 2026-05-29 Shubham Anand , Jens Elgeti , Gerhard Gompper

The coupled motion is investigated for a mechanical system consisting of water and a body freely floating in it. Water occupies either a half-space or a layer of constant depth into which an infinitely long surface-piercing cylinder is…

Mathematical Physics · Physics 2015-03-10 Nikolay Kuznetsov

We study the assembly of colloids in a two phase water-water system that provides an environment that can sustain bacteria, providing a new structure with rich potential to confine and structure living colloids. The water-water system,…

Soft Condensed Matter · Physics 2014-12-12 Sarah D. Hann , Mark Goulian , Daeyeon Lee , Kathleen J. Stebe
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