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By constructing a Landau-like energy functional, we investigate the molecular organization of a three-component mixture in cell membranes. In the strongly interacting limit, we model the interaction between molecules using pseudospin…

Biological Physics · Physics 2020-05-12 Austin Osby , Theja N. De Silva

The mechanical properties of a thin, planar material, perfused by an embedded flow network, can be changed locally and globally by the fluid transport and storage, resulting in small or large-scale deformation, such as out-of-plane…

Soft Condensed Matter · Physics 2023-03-15 Yongtian Luo , Che-Ling Ho , Brent R. Helliker , Eleni Katifori

We set up the statistical mechanics for a nearly flat, thermally equilibrated fluid membrane, attached to an elastic network through one of its sides. We predict that the resulting structural (inversion) asymmetry of the membrane, notably…

Soft Condensed Matter · Physics 2016-10-07 Tirthankar Banerjee , Niladri Sarkar , Abhik Basu

In growing plant cells, parallel ordering of microtubules (MTs) along the inner surface of the cell membrane influences the direction of cell expansion and thereby plant morphology. For correct expansion of organs that primarily grow by…

Biological Physics · Physics 2019-09-05 Sven Bachmann , Richard Froese , Eric N Cytrynbaum

We investigate the dynamics of membranes that are held by freely-rotating tethers in fluid flows. The tethered boundary condition allows periodic and chaotic oscillatory motions for certain parameter values. We characterize the oscillations…

Fluid Dynamics · Physics 2021-06-16 Christiana Mavroyiakoumou , Silas Alben

We consider a discrete-continuum model of a biomembrane with embedded particles. While the membrane is represented by a continuous surface, embedded particles are described by rigid discrete objects which are free to move and rotate in…

Analysis of PDEs · Mathematics 2021-04-29 Tobias Kies , Carsten Gräser

A remarkable property of flexible self-avoiding elastic surfaces (membranes) is that they remain flat at all temperatures, even in the absence of a bending rigidity or in the presence of active fluctuations. Here, we report numerical…

Soft Condensed Matter · Physics 2025-01-14 A. D. Chen , M. C. Gandikota , A. Cacciuto

Curvature-sensing and curvature-remodeling proteins are known to reshape cell membranes, and this remodeling event is essential for key biophysical processes such as tubulation, exocytosis, and endocytosis. Curvature-inducing proteins can…

Biological Physics · Physics 2015-10-13 Richard W. Tourdot , N. Ramakrishnan , Ravi Radhakrishnan

A mesoscopic coarse-grain model for computationally-efficient simulations of biomembranes is presented. It combines molecular dynamics simulations for the lipids, modeled as elastic chains of beads, with multiparticle collision dynamics for…

Soft Condensed Matter · Physics 2015-06-04 Mu-Jie Huang , Raymond Kapral , Alexander S. Mikhailov , Hsuan-Yi Chen

The shear-induced deformation of a capsule with a stiff nucleus, a model of eukaryotic cells, is studied numerically. The membrane of the cell and of its nucleus are modelled as a thin and impermeable elastic material obeying a Neo-Hookean…

Fluid Dynamics · Physics 2017-05-29 Arash Alizad Banaei , Jean-Christophe Loiseau , Iman Lashgari , Luca Brandt

Equilibrium self-assembly and conventional materials processing techniques fall far short of mimicking dynamic self-actuating processes that are commonplace throughout biology. To bridge the gap between living and synthetic matter, we study…

The effect of strong shear flow on highly fluctuating lamellar systems stabilized by intermembrane collisions via the Helfrich interaction is studied. Advection enters the microscopic equation of motion for a single membrane via a…

Soft Condensed Matter · Physics 2009-11-07 Simon W. Marlow , Peter D. Olmsted

The assembly of banana-shaped rodlike proteins on membranes, and the associated membrane shape transformations, are investigated by analytical theory and coarse-grained simulations. The membrane-mediated interactions between two…

Soft Condensed Matter · Physics 2017-05-15 Hiroshi Noguchi , Jean-Baptiste Fournier

This study investigates the coupled deformation and flow behavior of thin, hyper-elastic, porous membranes subjected to pressure loading. Using bulge test experiments, optical deformation measurements, and flow rate characterization, we…

Fluid Dynamics · Physics 2026-01-19 Alexander Gehrke , Zoe King , Kenneth S. Breuer

A nematic membrane is a sheet with embedded orientational order, which can occur in biological cells, liquid crystal films, manufactured materials, and other soft matter systems. By formulating the free energy of nematic films using tensor…

Soft Condensed Matter · Physics 2009-11-13 John R. Frank , Mehran Kardar

Active gel theory has recently been very successful in describing biologically active materials such as actin filaments or moving bacteria in temporally fixed and simple geometries such as cubes or spheres. Here we develop a computational…

Biological Physics · Physics 2019-07-10 Christian Bächer , Stephan Gekle

Topological defects are ubiquitous on surfaces with orientational order fields. Here, we study equilibrium states generated by the feedback between geometry and nematic order on fluid membranes with an integer topological defect. When the…

Soft Condensed Matter · Physics 2024-11-14 D. J. G. Pearce , C. Thibault , Q. Chaboche , C. Blanch-Mercader

We review the theoretical analyses and simulations of the interactions between curvature-inducing proteins and biomembranes. Laterally isotropic proteins induce spherical budding, whereas anisotropic proteins, such as Bin/Amphiphysin/Rvs…

Soft Condensed Matter · Physics 2023-03-10 Hiroshi Noguchi

The present work investigates the mechanical behaviour of finite-size, elastic and inertial fibres freely moving in a homogeneous and isotropic turbulent flow at moderate Reynolds number. Fully-resolved, direct numerical simulations, based…

Fluid Dynamics · Physics 2022-08-24 Stefano Olivieri , Andrea Mazzino , Marco E. Rosti

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast
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