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The plant microtubule cortical array is a striking feature of all growing plant cells. It consists of a more or less homogeneously distributed array of highly aligned microtubules connected to the inner side of the plasma membrane and…

Soft Condensed Matter · Physics 2013-05-29 Rhoda J. Hawkins , Simon H. Tindemans , Bela M. Mulder

In growing plant cells, parallel ordering of microtubules (MTs) along the inner surface of the cell membrane influences the direction of cell expansion and thereby plant morphology. For correct expansion of organs that primarily grow by…

Biological Physics · Physics 2019-09-05 Sven Bachmann , Richard Froese , Eric N Cytrynbaum

The dynamic behavior of microtubules in solution can be strongly modified by interactions with walls or other structures. We examine here a microtubule growth model where the increase in size of the plus-end is perturbed by collisions with…

Soft Condensed Matter · Physics 2010-09-29 Vladimir A. Baulin , Carlos M. Marques , Fabrice Thalmann

The microtubule cytoskeleton is comprised of dynamic, polarized filaments that facilitate transport within the cell. Polarized microtubule arrays are key to facilitating cargo transport in long cells such as neurons. Microtubules also…

Quantitative Methods · Quantitative Biology 2025-09-01 Hannah G. Scanlon , Gibarni Mahata , Anna C. Nelson , Scott A. McKinley , Melissa M. Rolls , Maria-Veronica Ciocanel

A theoretical model of stabilization of a microtubule assembly due to microtubule-associated-proteins(MAP) is presented. MAPs are assumed to bind to the microtubule filaments, thus preventing their disintegration following hydrolysis and…

Subcellular Processes · Quantitative Biology 2012-08-27 Bindu S. Govindan , William B. Spillman,

Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

The cortical microtubule array of dark-grown hypocotyl cells of plant seedlings undergoes a striking, and developmentally significant, reorientation upon exposure to light. This process is driven by the exponential amplification of a…

Biological Physics · Physics 2020-05-27 Marco Saltini , Bela M. Mulder

It is known that the orientation of cellulose microfibrils within plant cell walls has an important impact on the morphogenesis of plant cells and tissues. Viewing the shape of a plant cell as a square prism or cylinder with the axis…

Cell Behavior · Quantitative Biology 2015-09-17 Mariya Ptashnyk , Brian Seguin

Microtubules self-organize to form part of the cellular cytoskeleton. They give cells their shape and play a crucial role in cell division and intracellular transport. Strikingly, microtubules driven by motor proteins reorganize into stable…

Adaptation and Self-Organizing Systems · Physics 2024-05-16 Nikita Frolov , Bram Bijnens , Daniel Ruiz-Reynés , Lendert Gelens

We present a systematic study of the influence of cell geometry on the orientational distribution of microtubules (MTs) nucleated from a single microtubule organizing center (MTOC). For simplicity we consider an elliptical cell geometry, a…

Biomolecules · Quantitative Biology 2022-11-30 Panayiotis Foteinopoulos , Bela M. Mulder

Ordered polarity alignment of a cell population plays a vital role in biology, such as in hair follicle alignment and asymmetric cell division. Here, we propose a theoretical framework for the understanding of generic dynamical properties…

Pattern Formation and Solitons · Physics 2016-12-13 Kaori Sugimura , Hiroshi Kori

The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments…

Cell Behavior · Quantitative Biology 2016-02-17 Chuan Xue , Blerta Shtylla , Anthony Brown

This work discusses preliminary work aimed at simulating and visualizing the growth process of a tiny structure inside the cell---the microtubule. Difficulty of recording the process lies in the fact that the tissue preparation method for…

Computer Vision and Pattern Recognition · Computer Science 2011-05-31 Feiyang Yu , Ard Oerlemans , Erwin M. Bakker

The formation of microparticles requires the bending of the plasma membrane away from the cytosol. The capcity of the cell membrane to form a microparticle, and the rate of membrane deformation, are controlled by multiple factors, including…

Soft Condensed Matter · Physics 2024-02-13 Arijit Mahapatra , Sage A. Malingen , Padmini Rangamani

A powerful experimental approach for investigating computation in networks of biological neurons is the use of cultured dissociated cortical cells grown into networks on a multi-electrode array. Such preparations allow investigation of…

Neurons and Cognition · Quantitative Biology 2008-05-23 M. Stiber , F. Kawasaki , D. Xu

Microtubules are stiff filamentary proteins that constitute an important component of the cytoskeleton of cells. These are known to exhibit a dynamic instability. A steadily growing microtubule can suddenly start depolymerizing very…

Statistical Mechanics · Physics 2009-11-10 Pankaj Kumar Mishra , Ambarish Kunwar , Sutapa Mukherji , Debashish Chowdhury

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

Subcellular Processes · Quantitative Biology 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

Plant morphology emerges from cellular growth and structure. The turgor-driven diffuse growth of a cell can be highly anisotropic: significant longitudinally and negligible radially. Such anisotropy is ensured by cellulose microfibrils…

Quantitative Methods · Quantitative Biology 2022-08-23 Jeevanjyoti Chakraborty , Jingxi Luo , Rosemary J Dyson

The cytoskeleton is essential for the maintenance of cell morphology in eukaryotes. In fission yeast for example, polarized growth sites are organized by actin whereas microtubules (MT) acting upstream control where growth occurs (La…

Cell Behavior · Quantitative Biology 2009-03-30 Dietrich Foethke , Tatyana Makushok , Damian Brunner , Francois Nedelec

Cortical bone is a tough biological material composed of tube-like osteons embedded in the organic matrix surrounded by weak interfaces known as cement lines. The cement lines provide a microstructurally preferable crack path, hence…

Applied Physics · Physics 2024-05-24 Shashank Gupta , Reza Moini
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