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Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

What can we learn from a connectome? We constructed a simplified model of the first two stages of the fly visual system, the lamina and medulla. The resulting hexagonal lattice convolutional network was trained using backpropagation through…

Neurons and Cognition · Quantitative Biology 2018-06-26 Fabian David Tschopp , Michael B. Reiser , Srinivas C. Turaga

Model calculations have been performed on the spike-train response of a pair of Hodgkin-Huxley (HH) neurons coupled by recurrent excitatory-excitatory couplings with time delay. The coupled, excitable HH neurons are assumed to receive the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hideo Hasegawa

Brain encoder models predict cortical fMRI responses from the internal activations of pretrained vision and language networks, and are typically evaluated by held-out prediction accuracy. This is a useful signal for training but a poor one…

Neurons and Cognition · Quantitative Biology 2026-05-15 Stuart Bladon , Brinnae Bent

The manner in which groups of neurons represent events in the external world is fundamental to neuroscience. Here, we analyze the population code of the retina during naturalistic stimulation and show that the information conveyed by…

Neurons and Cognition · Quantitative Biology 2007-05-23 Elad Schneidman , Jason L. Puchalla , Ronen Segev , Robert A. Harris , William Bialek , Michael J. Berry

Networks of interconnected neurons communicating through spiking signals offer the bedrock of neural computations. Our brains spiking neural networks have the computational capacity to achieve complex pattern recognition and cognitive…

Neural and Evolutionary Computing · Computer Science 2024-12-06 Naresh Ravichandran , Anders Lansner , Pawel Herman

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

The human visual system is an intricate network of brain regions that enables us to recognize the world around us. Despite its abundant lateral and feedback connections, object processing is commonly viewed and studied as a feedforward…

Neurons and Cognition · Quantitative Biology 2019-10-09 Tim C Kietzmann , Courtney J Spoerer , Lynn Sörensen , Radoslaw M Cichy , Olaf Hauk , Nikolaus Kriegeskorte

To understand possible strategies of temporal spike coding in the central nervous system, we study functional neuromimetic models of visual processing for static images. We will first present the retinal model which was introduced by Van…

Neurons and Cognition · Quantitative Biology 2007-05-23 Laurent Perrinet , Manuel Samuelides , Simon Thorpe

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

In this correspondence information theoretical tools are used to investigate the statistical properties of modeled cochlear nucleus globular bushy cell spike trains. The firing patterns are obtained from a simulation software that generates…

Neurons and Cognition · Quantitative Biology 2012-04-25 Andrea Grigorescu , Marek Rudnicki , Michael Isik , Werner Hemmert , Stefano Rini

The retina is a complex nervous system which encodes visual stimuli before higher order processing occurs in the visual cortex. In this study we evaluated whether information about the stimuli received by the retina can be retrieved from…

Computer Vision and Pattern Recognition · Computer Science 2017-01-18 Matteo Zanotto , Riccardo Volpi , Alessandro Maccione , Luca Berdondini , Diego Sona , Vittorio Murino

Modern neural recording techniques allow neuroscientists to obtain spiking activity of multiple neurons from different brain regions over long time periods, which requires new statistical methods to be developed for understanding structure…

Applications · Statistics 2023-12-29 Ganchao Wei

Feedback-driven recurrent spiking neural networks (RSNNs) are powerful computational models that can mimic dynamical systems. However, the presence of a feedback loop from the readout to the recurrent layer de-stabilizes the learning…

Artificial Intelligence · Computer Science 2022-05-30 Ankita Paul , Stefan Wagner , Anup Das

Simultaneous recordings from many neurons hide important information and the connections characterizing the network remain generally undiscovered despite the progresses of statistical and machine learning techniques. Discerning the presence…

Applications · Statistics 2019-03-21 Pietro Verzelli , Laura Sacerdote

The relationship between a neuron's complex inputs and its spiking output defines the neuron's coding strategy. This is frequently and effectively modeled phenomenologically by one or more linear filters that extract the components of the…

Neurons and Cognition · Quantitative Biology 2011-11-02 Michael Famulare , Adrienne L. Fairhall

Understanding the activity of large populations of neurons is difficult due to the combinatorial complexity of possible cell-cell interactions. To reduce the complexity, coarse-graining had been previously applied to experimental neural…

Neurons and Cognition · Quantitative Biology 2021-03-24 Mia C. Morrell , Audrey J. Sederberg , Ilya Nemenman

We propose a method that would allow for a rigorous statistical analysis of neural responses to natural stimuli, which are non-Gaussian and exhibit strong correlations. We have in mind a model in which neurons are selective for a small…

Biological Physics · Physics 2007-05-23 Tatyana Sharpee , Nicole C. Rust , William Bialek

We analyze the response of the Hodgkin-Huxley neuron to a large number of uncorrelated stochastic inhibitory and excitatory post-synaptic spike trains. In order to clarify the various mechanisms responsible for noise-induced spike…

Disordered Systems and Neural Networks · Physics 2007-05-23 Alessandro Torcini , Stefano Luccioli , Thomas Kreuz

At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo