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Boundary layers play an important role in controlling convective heat transfer. Their nature varies considerably between different application areas characterized by different boundary conditions, which hampers a uniform treatment. Here, we…

Fluid Dynamics · Physics 2013-03-20 K. Petschel , S. Stellmach , M. Wilczek , J. Lülff , U. Hansen

The existence of temperature gradients within eukaryotic cells has been postulated as a source of natural convection in the cytoplasm, i.e. bulk fluid motion as a result of temperature-difference-induced density gradients. Recent…

Fluid Dynamics · Physics 2024-07-22 Nikhil Desai , Weida Liao , Eric Lauga

We study the motion of a rigid sphere falling in a two-layer stratified fluid under the action of gravity in the potential flow regime. Experiments at a moderate Reynolds number of approximately 20 to 450 indicate that a sphere with the…

Computation of biological processes creates great promise for everyday life and great challenges for physical scientists. Simulations of molecular dynamics appeal to biologists as a natural extension of structural biology. Once biologists…

Biomolecules · Quantitative Biology 2019-03-05 Bob Eisenberg

Motivated by a wide variety of applications, ranging from stochastic optimization to dimension reduction through variable selection, the problem of estimating gradients accurately is of crucial importance in statistics and learning theory.…

Machine Learning · Computer Science 2020-06-29 Guillaume Ausset , Stephan Clémençon , François Portier

Recent work has highlighted roles for thermodynamic phase behavior in diverse cellular processes. Proteins and nucleic acids can phase separate into three-dimensional liquid droplets in the cytoplasm and nucleus and the plasma membrane of…

Biological Physics · Physics 2022-02-23 Mason Rouches , Sarah Veatch , Benjamin Machta

The numerical analysis of elastic wave propagation in unbounded media may be difficult to handle due to spurious waves reflected at the model artificial boundaries. Several sophisticated techniques such as nonreflecting boundary conditions,…

Classical Physics · Physics 2010-09-06 Jean-François Semblat , Ali Gandomzadeh , Luca Lenti

By combining aspects of the coherent and self intermediate scattering functions, measured by dynamical light scattering on a suspension of hard sphere-like particles, we show that the arrest of particle number density fluctuations spreads…

Soft Condensed Matter · Physics 2015-05-13 W. van Megen , V. A. Martinez , G. Bryant

Neural representations are not unique objects. Even when two systems realize the same downstream computation, their hidden coordinates may differ by reparameterization. A probe family intended to reveal structure already present in a…

Machine Learning · Computer Science 2026-05-13 Su Hyeong Lee , Risi Kondor

We investigate single-cell directional sensing from diffusing chemoattractant signals released by a localized source. We focus on the low-concentration regime in which receptor activity is discrete and cellular decisions are made on…

Cell Behavior · Quantitative Biology 2026-03-12 Vincent Fiorino , Sean D. Lawley , Alan E. Lindsay

Finite volume methods for problems involving second order operators with full diffusion matrix can be used thanks to the definition of a discrete gradient for piecewise constant functions on unstructured meshes satisfying an orthogonality…

Numerical Analysis · Mathematics 2016-08-16 Robert Eymard , Thierry Gallouët , Raphaèle Herbin

We expand on a previous study of fronts in finite particle number reaction-diffusion systems in the presence of a reaction rate gradient in the direction of the front motion. We study the system via reaction-diffusion equations, using the…

Statistical Mechanics · Physics 2009-11-11 Elisheva Cohen , David A. Kessler , Herbert Levine

Various biological cells secrete diffusing chemical compounds into their environment for communication purposes. Secretion usually takes place over the cell membrane in a spatially heterogeneous manner. Mathematical models of these…

Numerical Analysis · Mathematics 2025-11-20 Qiyao Peng , Sander C. Hille

Tactile sensing for robotics is achieved through a variety of mechanisms, including magnetic, optical-tactile, and conductive fluid. Currently, the fluid-based sensors have struck the right balance of anthropomorphic sizes and shapes and…

Scientists have long sought to understand how vascular networks supply blood and oxygen to cells throughout the body. Recent work focuses on principles that constrain how vessel size changes through branching generations from the aorta to…

Tissues and Organs · Quantitative Biology 2015-09-10 Mitchell G Newberry , Daniel B Ennis , Van M Savage

Direct numerical simulations are used to study the interaction of a stream of small heavy inertial particles with the laminar and turbulent wakes of an immobile sphere facing an incompressible uniform inflow. Particles that do not collide…

Fluid Dynamics · Physics 2015-06-11 Holger Homann , Jérémie Bec

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey

We prove global well-posedness for some molecular beam epitaxy models. This requires proving some bounds on the gradient of solutions. We also obtain some global bounds on the roughness of solutions.

Analysis of PDEs · Mathematics 2021-04-26 Daniel Oliveira da Silva , Magzhan Biyar

Conventional classical sensors are approaching their maximum sensitivity levels in many areas. Yet these levels still are far from the ultimate limits dictated by quantum mechanics. Quantum sensors promise a substantial step ahead by taking…

Quantum Physics · Physics 2020-12-02 Aaron Z. Goldberg , Andrei B. Klimov , Gerd Leuchs , Luis L. Sanchez-Soto

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler