Related papers: Multilevel functional principal component analysis
The advance of modern sensor technologies enables collection of multi-stream longitudinal data where multiple signals from different units are collected in real-time. In this article, we present a non-parametric approach to predict the…
HIV-1C is the most prevalent subtype of HIV-1 and accounts for over half of HIV-1 infections worldwide. Host genetic influence of HIV infection has been previously studied in HIV-1B, but little attention has been paid to the more prevalent…
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common sleep disorder caused by upper airway blockage, leading to oxygen deprivation and disrupted sleep. Traditional diagnosis using polysomnography (PSG) is expensive, time-consuming,…
A powerful study design in the fields of genomics and metabolomics is the 'replicated time course experiment' where individual time series are observed for a sample of biological units, such as human patients, termed replicates. Standard…
Resting-state fMRI has been shown to provide surrogate biomarkers for the analysis of various diseases. In addition, fMRI data helps in understanding the brain's functional working during resting state and task-induced activity. To improve…
Principal component analysis (PCA) aims at estimating the direction of maximal variability of a high-dimensional dataset. A natural question is: does this task become easier, and estimation more accurate, when we exploit additional…
Polysomnography (PSG) is an indispensable diagnostic tool in sleep medicine, essential for identifying various sleep disorders. By capturing physiological signals, including EEG, EOG, EMG, and cardiorespiratory metrics, PSG presents a…
Multi-channel photoplethysmography (PPG) sensors have found widespread adoption in wearable devices for monitoring cardiac health. Channels thereby serve different functions -- whereas green is commonly used for metrics such as heart rate…
Hyperalignment has been widely employed in Multivariate Pattern (MVP) analysis to discover the cognitive states in the human brains based on multi-subject functional Magnetic Resonance Imaging (fMRI) datasets. Most of the existing HA…
Principal Component analysis (PCA) is a useful statistical technique that is commonly used for multivariate analysis of correlated variables. It is usually applied as a dimension reduction method: the top principal components (PCs)…
We present a novel method, Fractal Space-Curve Analysis (FSCA), which combines Space-Filling Curve (SFC) mapping for dimensionality reduction with fractal Detrended Fluctuation Analysis (DFA). The method is suitable for multidimensional…
While the shift toward unified foundation models has revolutionized many deep learning domains, sleep medicine remains largely restricted to task-specific models that focus on localized micro-structure features. These approaches often…
We propose a new fast generalized functional principal components analysis (fast-GFPCA) algorithm for dimension reduction of non-Gaussian functional data. The method consists of: (1) binning the data within the functional domain; (2)…
This article considers the problem of analyzing associations between power spectra of multiple time series and cross-sectional outcomes when data are observed from multiple subjects. The motivating application comes from sleep medicine,…
Echocardiography (echo) is an ultrasound imaging modality that is widely used for various cardiovascular diagnosis tasks. Due to inter-observer variability in echo-based diagnosis, which arises from the variability in echo image acquisition…
Despite extensive research on the relationship between sleep and cognition, the connection between sleep microstructure and human performance across specific cognitive domains remains underexplored. This study investigates whether deep…
An important step in speaker verification is extracting features that best characterize the speaker voice. This paper investigates a front-end processing that aims at improving the performance of speaker verification based on the SVMs…
Sleep apnea is the most common sleep disturbance and it is an important risk factor for cardiovascular disorders. Its detection relies on a polysomnography, a combination of diverse exams. In order to detect changes due to sleep…
Reliable sleep staging remains challenging for lightweight wearable devices such as single-channel electroencephalography (scEEG) or photoplethysmography (PPG). scEEG offers direct measurement of cortical activity and serves as the…
With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic…