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Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Applications · Statistics 2025-01-03 Xiaojing Sun , Bingxin Zhao , Fei Xue

Electroencephalography (EEG) is a tool that allows us to analyze brain activity with high temporal resolution. These measures, combined with deep learning and digital signal processing, are widely used in neurological disorder detection and…

Signal Processing · Electrical Eng. & Systems 2024-11-20 Isaac Ariza , Lorenzo J. Tardon , Ana M. Barbancho , Irene De-Torres , Isabel Barbancho

Mobile health studies often collect multiple within-day self-reported assessments of participants' behavior and well-being on different scales such as physical activity (continuous), pain levels (truncated), mood states (ordinal), and life…

Methodology · Statistics 2023-09-22 Debangan Dey , Rahul Ghosal , Kathleen Merikangas , Vadim Zipunnikov

Sleep apnea (SA) is a type of sleep disorder characterized by snoring and chronic sleeplessness, which can lead to serious conditions such as high blood pressure, heart failure, and cardiomyopathy (enlargement of the muscle tissue of the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Anh-Tu Nguyen , Thao Nguyen , Huy-Khiem Le , Huy-Hieu Pham , Cuong Do

Sleep is the primary mean of recovery from accumulated fatigue and thus plays a crucial role in fostering people's mental and physical well-being. Sleep quality monitoring systems are often implemented using wearables that leverage their…

Human-Computer Interaction · Computer Science 2023-08-15 Nouran Abdalazim , Leonardo Alchieri , Lidia Alecci , Silvia Santini

Resting state electroencephalogram (EEG) abnormalities in clinically high-risk individuals (CHR), clinically stable first-episode patients with schizophrenia (FES), healthy controls (HC) suggest alterations in neural oscillatory activity.…

Signal Processing · Electrical Eng. & Systems 2018-01-18 Haichun Liu , TianHong Zhang , Yumeng Ye , Changchun Pan , Genke Yang , JiJun Wang , Robert C. Qiu

We present a new statistical method to analyze multichannel steady-state local field potentials (LFP) recorded within different sensory cortices of different rodent species. Our spatiotemporal multi-dimensional cluster statistics (MCS)…

Quantitative Methods · Quantitative Biology 2016-11-24 Patrick Krauss , Claus Metzner , Achim Schilling , Konstantin Tziridis , Maximilian Traxdorf , Holger Schulze

Federated techniques such as federated learning and federated analysis have emerged as a powerful paradigm for enabling multi-center research on sensitive clinical data while preserving patient privacy. In this study, we introduce a…

Machine Learning · Computer Science 2026-05-12 Evelyn Trautmann , Joël Federer-Gsponer , Markus C. Elze , José-Tomás Prieto

Obstructive sleep apnea (OSA) is a common sleep disorder caused by abnormal breathing. The severity of OSA can lead to many symptoms such as sudden cardiac death (SCD). Polysomnography (PSG) is a gold standard for OSA diagnosis. It records…

Signal Processing · Electrical Eng. & Systems 2020-07-28 Nannapas Banluesombatkul , Thanawin Rakthanmanon , Theerawit Wilaiprasitporn

Functional principal component analysis (FPCA) is a key tool in the study of functional data, driving both exploratory analyses and feature construction for use in formal modeling and testing procedures. However, existing methods for FPCA…

Methodology · Statistics 2026-03-24 Caitrin Murphy , Eric Laber , Rhonda Merwin , Brian Reich , Jake Koerner

Accurate segmentation of coronary arteries is a pivotal process in assessing cardiovascular diseases. However, the intricate structure of the cardiovascular system presents significant challenges for automatic segmentation, especially when…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Jonghoe Ku , Yong-Hee Lee , Junsup Shin , In Kyu Lee , Hyun-Woo Kim

Functional data analysis on nonlinear manifolds has drawn recent interest. Sphere-valued functional data, which are encountered for example as movement trajectories on the surface of the earth, are an important special case. We consider an…

Statistics Theory · Mathematics 2017-10-25 Xiongtao Dai , Hans-Georg Müller

The monitoring of sleep patterns without patient's inconvenience or involvement of a medical specialist is a clinical question of significant importance. To this end, we propose an automatic sleep stage monitoring system based on an…

Medical Physics · Physics 2017-01-17 Takashi Nakamura , Valentin Goverdovsky , Mary J. Morrell , Danilo P. Mandic

Functional time series (FTS) data have become increasingly available in real-world applications. Research on such data typically focuses on two objectives: curve reconstruction and forecasting, both of which require efficient dimension…

Methodology · Statistics 2025-06-23 Zerui Guo , Jianbin Tan , Hui Huang

Sleep stage classification is a widely discussed topic, due to its importance in the diagnosis of sleep disorders, e.g. insomnia. Analysis of the brain activity during sleep is necessary to gain further insight into the processing that…

Signal Processing · Electrical Eng. & Systems 2024-10-08 Alexander Edthofer , Iris Feldhammer , Thomas Fenzl , Andreas Körner , Matthias Kreuzer

Data with multiple functional recordings at each observational unit are increasingly common in various fields including medical imaging and environmental sciences. To conduct inference for such observations, we develop a paired two-sample…

Methodology · Statistics 2025-06-16 Colin Decker , Dehan Kong , Stanislav Volgushev

Sleep staging plays an important role on the diagnosis of sleep disorders. In general, experts classify sleep stages manually based on polysomnography (PSG), which is quite time-consuming. Meanwhile, the acquisition process of multiple…

Machine Learning · Computer Science 2021-08-17 Huafeng Wang , Chonggang Lu , Qi Zhang , Zhimin Hu , Xiaodong Yuan , Pingshu Zhang , Wanquan Liu

Sleep disturbances are tightly linked to cardiovascular risk, yet polysomnography (PSG)-the clinical reference standard-remains resource-intensive and poorly suited for multi-night, home-based, and large-scale screening. Single-lead…

Signal Processing · Electrical Eng. & Systems 2026-03-20 Donglin Xie , Qingshuo Zhao , Jingyu Wang , Shijia Geng , Jiarui Jin , Jun Li , Rongrong Guo , Guangkun Nie , Gongzheng Tang , Yuxi Zhou , Thomas Penzel , Shenda Hong

This paper introduces a robust approach to functional principal component analysis (FPCA) for relative data, particularly density functions. While recent papers have studied density data within the Bayes space framework, there has been…

Mixtures of probabilistic principal component analysis (MPPCA) is a well-known mixture model extension of principal component analysis (PCA). Similar to PCA, MPPCA assumes the data samples in each mixture contain homoscedastic noise.…

Methodology · Statistics 2023-01-27 Alec S. Xu , Laura Balzano , Jeffrey A. Fessler
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