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Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are an effective tool for studying cardiac function and disease, and hold promise for screening drug effects on human tissue. Changes to motion patterns in these cells…

Tissues and Organs · Quantitative Biology 2024-07-09 Henrik Finsberg , Verena Charwat , Kevin Healy , Samuel Wall

Task-based programming models are emerging as a promising alternative to make the most of multi-/many-core systems. These programming models rely on runtime systems, and their goal is to improve application performance by properly…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-24 Antoni Navarro , Arthur F. Lorenzon , Eduard Ayguadé , Vicenç Beltran

Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint…

Physically accurate and mathematically tractable models are presented to characterize scattering and reflection properties of reconfigurable intelligent surfaces (RISs). We take continuous and discrete strategies to model a single patch and…

Systems and Control · Electrical Eng. & Systems 2022-08-31 Tiebin Mi , Jianan Zhang , Rujing Xiong , Zhengyu Wang , Robert Caiming Qiu

Efficient utility of radio spectrum has been a hot topic as the wireless communication spectrum is a precious resource. The past decade has witnessed intensive research in spectrum sharing techniques. Most of the techniques are based on…

Networking and Internet Architecture · Computer Science 2018-08-30 Qi Dong , Yu Chen , Xiaohua Li , Kai Zeng

Despite the growing availability of sensing and data in general, we remain unable to fully characterise many in-service engineering systems and structures from a purely data-driven approach. The vast data and resources available to capture…

Machine Learning · Computer Science 2023-09-20 Elizabeth J Cross , Timothy J Rogers , Daniel J Pitchforth , Samuel J Gibson , Matthew R Jones

Many future innovative computing services will use Fog Computing Systems (FCS), integrated with Internet of Things (IoT) resources. These new services, built on the convergence of several distinct technologies, need to fulfil time-sensitive…

Cryptography and Security · Computer Science 2020-07-20 Jose Moura , David Hutchison

The increasing integration of renewable energy sources (RESs) into modern power systems presents significant opportunities but also notable challenges, primarily due to the inherent variability of RES generation. Accurate forecasting of RES…

Machine Learning · Computer Science 2026-01-19 Farshid Kamrani , Kristen Schell

Restricted Boltzmann machine (RBM) provide a general framework for modeling physical systems, but their behavior is dependent on hyperparameters such as the learning rate, the number of hidden nodes and the form of the threshold function.…

Computational Physics · Physics 2020-04-28 David Yevick , Roger Melko

Point masses connected by springs, or mass-spring systems, are widely used in computer animation to approximate the behavior of deformable objects. One of the restrictions imposed by these models is that points that are not topologically…

Graphics · Computer Science 2025-01-29 Zhiyuan Zhang , Krzysztof Grykiel , Zhaocheng Liu , Stefanos Papanicolopulos , Kartic Subr

In this paper, we consider a multi-user multiple-input multiple-output (MIMO) system aided by multiple intelligent reflecting surfaces (IRSs) that are deployed to increase the coverage and, possibly, the rank of the channel. We propose an…

Information Theory · Computer Science 2020-12-22 Andrea Abrardo , Davide Dardari , Marco Di Renzo

Cloud computing based systems, that span data centers, are commonly deployed to offer high performance for user service requests. As data centers continue to expand, computer architects and system designers are facing many challenges on how…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-08 Fan Yao , Kathy Ngyugen , Sai Santosh Dayapule , Jingxin Wu , Bingqian Lu , Suresh Subramaniam , Guru Venkataramani

State-space models are ubiquitous in the statistical literature since they provide a flexible and interpretable framework for analyzing many time series. In most practical applications, the state-space model is specified through a…

Methodology · Statistics 2020-06-18 Thi Tuyet Trang Chau , Pierre Ailliot , Valérie Monbet

Markov state models (MSMs) are a powerful tool to analyze and coarse-grain complex dynamical data into interpretable kinetic processes. This capability is particularly important in heterogeneous catalysis, where a medley of reactants and…

Statistical Mechanics · Physics 2026-05-11 Caitlin A. McCandler , Chatipat Lorpaiboon , Timothy C. Berkelbach , Jutta Rogal

Training LLMs in distributed environments presents significant challenges due to the complexity of model execution, deployment systems, and the vast space of configurable strategies. Although various optimization techniques exist, achieving…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-15 Mingyu Liang , Hiwot Tadese Kassa , Wenyin Fu , Brian Coutinho , Louis Feng , Christina Delimitrou

Chance-constrained optimization has emerged as a promising framework for managing uncertainties in power systems. This work advances its application to the DC Optimal Power Flow (DC-OPF) model, developing a novel approach to uncertainty…

Systems and Control · Electrical Eng. & Systems 2026-03-18 Tianyang Yi , D. Adrian Maldonado , Anirudh Subramanyam

Modeling complex dynamical systems under varying conditions is computationally intensive, often rendering high-fidelity simulations intractable. Although reduced-order models (ROMs) offer a promising solution, current methods often struggle…

Machine Learning · Computer Science 2026-01-16 Andrew F. Ilersich , Kevin Course , Prasanth B. Nair

The escalating computational demands and energy footprint of GPU-accelerated computing systems complicate informed design and operational decisions. We present the first release of Wattlytics (https://wattlytics.netlify.app), an…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-10 Ayesha Afzal , Georg Hager , Gerhard Wellein

Renewable energy projects, such as large offshore wind farms, are critical to achieving low-emission targets set by governments. Stochastic computer models allow us to explore future scenarios to aid decision making whilst considering the…

Methodology · Statistics 2021-12-07 Jack C. Kennedy , Daniel A. Henderson , Kevin J. Wilson

Single-molecule spectroscopy (SMS) is an exceptionally sensitive technique, but its inherently limited photon budget produces noisy data that can readily lead to subjective analyses, fitting errors, and reduced statistical power, obscuring…

Biological Physics · Physics 2026-03-19 Michael Lovemore , Joshua Botha , Bertus van Heerden , Tjaart Kruger