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Kinetic models of biochemical systems used in the modern literature often contain hundreds or even thousands of variables. While these models are convenient for detailed simulations, their size is often an obstacle to deriving mechanistic…

Molecular Networks · Quantitative Biology 2021-06-29 Gleb Pogudin , Xingjian Zhang

The incorporation of cutting planes within the branch-and-bound algorithm, known as branch-and-cut, forms the backbone of modern integer programming solvers. These solvers are the foremost method for solving discrete optimization problems…

Optimization and Control · Mathematics 2022-04-18 Maria-Florina Balcan , Siddharth Prasad , Tuomas Sandholm , Ellen Vitercik

Exact real computation is an alternative to floating-point arithmetic where operations on real numbers are performed exactly, without the introduction of rounding errors. When proving the correctness of an implementation, one can focus…

Logic in Computer Science · Computer Science 2024-10-22 Michal Konečný , Sewon Park , Holger Thies

Data-driven inverse optimization for mixed-integer linear programs (MILPs), which seeks to learn an objective function and constraints consistent with observed decisions, is important for building accurate mathematical models in a variety…

Optimization and Control · Mathematics 2026-02-17 Akira Kitaoka

We develop a constructive theory of continuous domains from the perspective of program extraction. Our goal that programs represent (provably correct) computation without witnesses of correctness is achieved by formulating correctness…

Logic in Computer Science · Computer Science 2023-06-22 Dirk Pattinson , Mina Mohammadian

We examine the consequences of having a total division operation $\frac{x}{y}$ on commutative rings. We consider two forms of binary division, one derived from a unary inverse, the other defined directly as a general operation; each are…

Logic in Computer Science · Computer Science 2024-12-25 Jan A Bergstra , John V Tucker

We begin to study classical dimension theory from the computable analysis (TTE) point of view. For computable metric spaces, several effectivisations of zero-dimensionality are shown to be equivalent. The part of this characterisation that…

Logic · Mathematics 2015-07-01 Robert Kenny

In the present paper we formally define the notion of abstract program slicing, a general form of program slicing where properties of data are considered instead of their exact value. This approach is applied to a language with numeric and…

Logic in Computer Science · Computer Science 2016-05-20 Isabella Mastroeni , Damiano Zanardini

In this work, we study linear error-correcting codes against adversarial insertion-deletion (indel) errors. While most constructions for the indel model are nonlinear, linear codes offer compact representations, efficient encoding, and…

Information Theory · Computer Science 2025-10-01 Roee Gross , Roni Con , Eitan Yaakobi

Cutting planes for mixed-integer linear programs (MILPs) are typically computed in rounds by iteratively solving optimization problems, the so-called separation. Instead, we reframe the problem of finding good cutting planes as a continuous…

Optimization and Control · Mathematics 2023-07-10 Didier Chételat , Andrea Lodi

Automatic differentiation---the mechanical transformation of numeric computer programs to calculate derivatives efficiently and accurately---dates to the origin of the computer age. Reverse mode automatic differentiation both antedates and…

Machine Learning · Computer Science 2014-04-30 Atilim Gunes Baydin , Barak A. Pearlmutter

We consider the model of random trees introduced by Devroye [SIAM J. Comput. 28 (1999) 409-432]. The model encompasses many important randomized algorithms and data structures. The pieces of data (items) are stored in a randomized fashion…

Probability · Mathematics 2012-11-05 Nicolas Broutin , Cecilia Holmgren

Farkas' lemma is a fundamental result from linear programming providing linear certificates for infeasibility of systems of linear inequalities. In semidefinite programming, such linear certificates only exist for strongly infeasible linear…

Optimization and Control · Mathematics 2018-04-27 Igor Klep , Markus Schweighofer

Algorithms for model checking and satisfiability of the modal $\mu$-calculus start by converting formulas to alternating parity tree automata. Thus, model checking is reduced to checking acceptance by tree automata and satisfiability to…

Logic in Computer Science · Computer Science 2022-08-24 Daniel Hausmann , Nir Piterman

We extend the maximal unitarity method to amplitude contributions whose cuts define multidimensional algebraic varieties. The technique is valid to all orders and is explicitly demonstrated at three loops in gauge theories with any number…

High Energy Physics - Theory · Physics 2014-06-20 Mads Sogaard , Yang Zhang

Branch and cut is the dominant paradigm for solving a wide range of mathematical programming problems -- linear or nonlinear -- combining efficient search (via branch and bound) and relaxation-tightening procedures (via cutting planes, or…

Optimization and Control · Mathematics 2023-07-11 Aleksandr M. Kazachkov , Pierre Le Bodic , Sriram Sankaranarayanan

In this paper, we introduce the first method that (1) can complete kernel matrices with completely missing rows and columns as opposed to individual missing kernel values, (2) does not require any of the kernels to be complete a priori, and…

Machine Learning · Computer Science 2016-02-09 Sahely Bhadra , Samuel Kaski , Juho Rousu

We introduce the notion of an ACP process algebra and the notion of a meadow enriched ACP process algebra. The former notion originates from the models of the axiom system ACP. The latter notion is a simple generalization of the former…

Logic in Computer Science · Computer Science 2013-08-07 J. A. Bergstra , C. A. Middelburg

Every partial function from bit strings of a given length to bit strings of a possibly different given length can be computed by a finite instruction sequence that contains only instructions to set and get the content of Boolean registers,…

Logic in Computer Science · Computer Science 2015-07-28 J. A. Bergstra , C. A. Middelburg

$\mathbb{Q}_0$ - the involutive meadow of the rational numbers - is the field of the rational numbers where the multiplicative inverse operation is made total by imposing $0^{-1}=0$. In this note, we prove that $\mathbb{Q}_0$ cannot be…

Rings and Algebras · Mathematics 2017-12-05 Jan A. Bergstra , Inge Bethke