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Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of…

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

We present a modified \emph{susceptible-infected-susceptible} (SIS) model on complex networks, small-world and scale-free, to study epidemic spreading with the effect of time delay which is introduced to the infected phase. Considering the…

Physics and Society · Physics 2009-11-11 Xin-Jian Xu , Hai-Ou Peng , Xiao-Mei Wang , Ying-Hai Wang

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

Understanding spreading dynamics will benefit society as a whole in better preventing and controlling diseases, as well as facilitating the socially responsible information while depressing destructive rumors. In network-based spreading…

Physics and Society · Physics 2015-01-16 Ai-Xiang Cui , Zimo Yang , Tao Zhou

Infectious disease remains, despite centuries of work to control and mitigate its effects, a major problem facing humanity. This paper reviews the mathematical modelling of infectious disease epidemics on networks, starting from the…

Popular Physics · Physics 2015-06-03 Thomas House

One of the popular dynamics on complex networks is the epidemic spreading. An epidemic model describes how infections spread throughout a network. Among the compartmental models used to describe epidemics, the…

Physics and Society · Physics 2011-07-14 Faryad Darabi Sahneh , Caterina Scoglio

We calculate epidemic thresholds and investigate the dynamics of a disease in a networked metapopulation model. To study the specific role of mobility levels and network geometry, we utilize the SIR-Network model and consider a range of…

Physics and Society · Physics 2023-08-07 Haridas K. Das , Lucas M. Stolerman

We study the problem of estimating the parameters (i.e., infection rate and recovery rate) governing the spread of epidemics in networks. Such parameters are typically estimated by measuring various characteristics (such as the number of…

Systems and Control · Electrical Eng. & Systems 2021-05-12 Lintao Ye , Philip E. Paré , Shreyas Sundaram

Infectious disease superspreading caused by heterogeneity in contact behavior has been observed to be an important determinant of epidemic dynamics and size in both empirical and theoretical settings. However, it has also been observed that…

Populations and Evolution · Quantitative Biology 2026-01-27 Ari S. Freedman , Bjarke F. Nielsen , Maximillian M. Nguyen , Laurent Hébert-Dufresne , Simon A. Levin

Our chances to halt epidemic outbreaks rely on how accurately we represent the population structure underlying the disease spread. When analyzing global epidemics this force us to consider metapopulation models taking into account intra-…

Populations and Evolution · Quantitative Biology 2007-12-10 Alexei Vazquez

Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

Populations and Evolution · Quantitative Biology 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

Most infectious diseases spread on a dynamic network of human interactions. Recent studies of social dynamics have provided evidence that spreading patterns may depend strongly on detailed micro-dynamics of the social system. We have…

Physics and Society · Physics 2015-09-23 Arkadiusz Stopczynski , Alex Sandy Pentland , Sune Lehmann

A major achievement in the study of complex networks is the observation that diverse systems, from sub-cellular biology to social networks, exhibit universal topological characteristics. Yet this universality does not naturally translate to…

Physics and Society · Physics 2018-01-29 Chittaranjan Hens , Uzi Harush , Reuven Cohen , Baruch Barzel

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

In stochastic modeling of infectious diseases, it has been established that variations in infectivity affect the probability of a major outbreak, but not the shape of the curves during a major outbreak, which is predicted by deterministic…

Physics and Society · Physics 2022-12-12 F Rousse , M Carlsson , M Ogren , B Kalischer Wellander

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

We model the spread of a SIS infection on Small World and random networks using weighted graphs. The entry $w_{ij}$ in the weight matrix W holds information about the transmission probability along the edge joining node $v_i$ and node…

General Mathematics · Mathematics 2007-05-23 Britta Daudert , Bai-Lian Li