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Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

3D Gaussian Splatting (3DGS) has emerged as a mainstream solution for novel view synthesis and 3D reconstruction. By explicitly encoding a 3D scene using a collection of Gaussian kernels, 3DGS achieves high-quality rendering with superior…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Lei Lan , Tianjia Shao , Zixuan Lu , Yu Zhang , Chenfanfu Jiang , Yin Yang

We present an efficient implementation of periodic Gaussian density fitting (GDF) using the Coulomb metric. The three-center integrals are divided into two parts by range-separating the Coulomb kernel, with the short-range part evaluated in…

Chemical Physics · Physics 2021-04-08 Hong-Zhou Ye , Timothy C. Berkelbach

This paper addresses the problem of blind demixing of instantaneous mixtures in a multiple-input multiple-output communication system. The main objective is to present efficient blind source separation (BSS) algorithms dedicated to moderate…

Information Theory · Computer Science 2016-06-30 Syed A. W. Shah , Karim Abed-Meraim , Tareq Y. Al-Naffouri

Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…

Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…

Tomography medical imaging is essential in the clinical workflow of modern cancer radiotherapy. Radiation oncologists identify cancerous tissues, applying delineation on treatment regions throughout all image slices. This kind of task is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Chun-Hung Chao , Yen-Chi Cheng , Hsien-Tzu Cheng , Chi-Wen Huang , Tsung-Ying Ho , Chen-Kan Tseng , Le Lu , Min Sun

The next great leap toward improving treatment of cancer with radiation will require the combined use of online adaptive and magnetic resonance guided radiation therapy techniques with automatic X-ray beam orientation selection.…

Medical Physics · Physics 2019-08-14 Ryan Neph , Yangsibo Huang , Youming Yang , Ke Sheng

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…

Medical Physics · Physics 2021-08-24 Yair Censor , Keith E. Schubert , Reinhard W. Schulte

We propose a new, two-stage algorithm for inverting strong gravitational lenses. The key to the algorithm is decoupling the effects of lens magnification and intrinsic structure in the background source in the appearance of lensed arcs.…

Astrophysics · Physics 2007-05-23 P. Newbury , G. G. Fahlman

$Objective$. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the…

Instrumentation and Detectors · Physics 2022-09-28 Atiq. Ur. Rahman , Mythra Varun. Nemallapudi , Cheng-Ying. Chou , Shih-Chang Lee , Chih-Hsun. Lin

Treatment planning, which is a critical component of the radiotherapy workflow, is typically carried out by a medical physicist in a time-consuming trial-and-error manner. Previous studies have proposed knowledge-based or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Yiwen Zhang , Chuanpu Li , Liming Zhong , Zeli Chen , Wei Yang , Xuetao Wang

Diffusion models have recently shown remarkable results in magnetic resonance imaging reconstruction. However, the employed networks typically are black-box estimators of the (smoothed) prior score with tens of millions of parameters,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-16 Laurenz Nagler , Martin Zach , Thomas Pock

3D Gaussian Splatting (3DGS) has emerged as a promising 3D reconstruction technique. The traditional 3DGS training pipeline follows three sequential steps: Gaussian densification, Gaussian projection, and color splatting. Despite its…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Junyi Wu , Jiaming Xu , Jinhao Li , Yongkang Zhou , Jiayi Pan , Xingyang Li , Guohao Dai

A mathematical algorithm is described for calculating the minimum distance between prisms and the allowable prism insertion depth into the laser beam when solving the general problem of intracavity group delay dispersion (GDD) compensation.…

Microbeam radiation therapy (MRT) utilizes coplanar synchrotron radiation beamlets and is a proposed treatment approach for several tumour diagnoses that currently have poor clinical treatment outcomes, such as gliosarcomas. Prescription…

Treatment planning system calculations in inhomogeneous regions may present significant inaccuracies due to loss of electronic equilibrium. In this study, three different dose calculation algorithms, pencil beam, collapsed cone, and…

Medical Physics · Physics 2015-03-12 Sung Jin Kim , Dong Ho Kim , Sung Kyu Kim

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

Medical Physics · Physics 2015-06-15 Hamed Yarmand , David Craft