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We review the mathematical formalism underlying the modelling of stochasticity in biological systems. Beginning with a description of the system in terms of its basic constituents, we derive the mesoscopic equations governing the dynamics…

Populations and Evolution · Quantitative Biology 2012-11-05 Alan J. McKane , Tommaso Biancalani , Tim Rogers

Spatial heterogeneity is a hallmark of living systems, even at the molecular scale in individual cells. A key example is the partitioning of membrane-bound proteins via lipid domain formation or cytoskeleton-induced corralling. Yet the…

Molecular Networks · Quantitative Biology 2013-11-19 Andrew Mugler , Filipe Tostevin , Pieter Rein ten Wolde

Stochastic Spatio-Temporal processes are prevalent across domains ranging from modeling of plasma to the turbulence in fluids to the wave function of quantum systems. This letter studies a measure-theoretic description of such systems by…

Optimization and Control · Mathematics 2021-05-25 George I. Boutselis , Ethan N. Evans , Marcus A. Pereira , Evangelos A. Theodorou

We show that the simplest stochastic epidemiological models with spatial correlations exhibit two types of oscillatory behaviour in the endemic phase. In a large parameter range, the oscillations are due to resonant amplification of…

Populations and Evolution · Quantitative Biology 2009-06-02 Ganna Rozhnova , Ana Nunes

We study the stochastic evolution of four species in cyclic competition in a well mixed environment. In systems composed of a finite number $N$ of particles these simple interaction rules result in a rich variety of extinction scenarios,…

Statistical Mechanics · Physics 2012-07-09 C. H. Durney , S. O. Case , M. Pleimling , R. K. P. Zia

In this paper we introduce a class of stochastic population models based on "patch dynamics". The size of the patch may be varied, and this allows one to quantify the departures of these stochastic models from various mean field theories,…

Populations and Evolution · Quantitative Biology 2009-11-11 A. J. McKane , T. J. Newman

Stochastic diffusion is the noisy and uncertain process through which dynamics like epidemics, or agents like animal species, disperse over a larger area. Understanding these processes is becoming increasingly important as we attempt to…

In this paper we analyze the equilibrium properties of a large class of stochastic processes describing the fundamental biological process within bacterial cells, {\em the production process of proteins}. Stochastic models classically used…

Molecular Networks · Quantitative Biology 2019-10-17 Philippe Robert

A stochastic model, the product of a circulant matrix and a random normal vector, is shown to produce an evolutive long memory time series with a power law spectral density. The distribution of the time series, a beta location scale family…

General Mathematics · Mathematics 2026-02-26 Robert Kimberk

Models of active nematics in biological systems normally require complexity arising from the hydrodynamics involved at the microscopic level as well as the viscoelastic nature of the system. Here we show that a minimal, space-independent,…

Soft Condensed Matter · Physics 2022-06-27 Emmanuel L. C. VI M. Plan , Huong Le Thi , Julia M. Yeomans , Amin Doostmohammadi

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

The study of biological cells in terms of mesoscopic, nonequilibrium, nonlinear, stochastic dynamics of open chemical systems provides a paradigm for other complex, self-organizing systems with ultra-fast stochastic fluctuations, short-time…

Chemical Physics · Physics 2014-11-06 Hong Qian

We study stochastic particle systems on a complete graph and derive effective mean-field rate equations in the limit of diverging system size, which are also known from cluster aggregation models. We establish the propagation of chaos under…

Probability · Mathematics 2021-07-21 Watthanan Jatuviriyapornchai , Stefan Grosskinsky

In particle-based computer simulations of polydisperse glassforming systems, the particle diameters $\sigma = \sigma_1, \dots, \sigma_N$ of a system with $N$ particles are chosen with the intention to approximate a desired distribution…

Soft Condensed Matter · Physics 2022-12-14 Niklas Küchler , Jürgen Horbach

Inspired by recent studies on deterministic oscillator models, we introduce a stochastic one-dimensional model for a chain of interacting particles. The model consists of $N$ oscillators performing continuous-time random walks on the…

Statistical Mechanics · Physics 2026-02-04 Emilio N. M. Cirillo , Matteo Colangeli , Claudio Giberti , Lamberto Rondoni

Traditional models of wormlike chains in shear flows at finite temperature approximate the equation of motion via finite difference discretization (bead and rod models). We introduce here a new method based on a spectral representation in…

Soft Condensed Matter · Physics 2007-05-23 Chris H. Wiggins , Alberto Montesi , Matteo Pasquali

This paper is devoted to the study of a stochastic epidemiological model which is a variant of the SIR model to which we add an extra factor in the transition rate from susceptible to infected accounting for the inflow of infection due to…

Analysis of PDEs · Mathematics 2021-06-29 Gadi Fibich , Samuel Nordmann

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

Cells achieve size homeostasis by regulating their division timing based on their size, added size, and cell cycle time. Previous research under steady-state conditions demonstrated the robustness of these mechanisms. However, their dynamic…

Quantitative Methods · Quantitative Biology 2025-12-01 Cesar Nieto , Sayeh Rezaee , Cesar Augusto Vargas-Garcia , Abhyudai Singh

Since the early 1970s, stellar population modelling has been one of the basic tools for understanding the physics of unresolved systems from observation of their integrated light. Models allow us to relate the integrated spectra (or…

Instrumentation and Methods for Astrophysics · Physics 2013-12-03 Miguel Cerviño
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