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Reverse engineering (RE) of x86 binaries is indispensable for malware and firmware analysis, but remains slow due to stripped metadata and adversarial obfuscation. Large Language Models (LLMs) offer potential for improving RE efficiency…

Cryptography and Security · Computer Science 2026-03-09 Darrin Lea , James Ghawaly , Golden Richard , Aisha Ali-Gombe , Andrew Case

We present new ways of producing a channel chart [1] employing model-based approaches. We estimate the angle of arrival theta and the distance rho between the base station and the user equipment by employing our algorithms, inverse of the…

Emerging Technologies · Computer Science 2025-05-13 Amr Aly , Ender Ayanoglu

Time-series of high throughput gene sequencing data intended for gene regulatory network (GRN) inference are often short due to the high costs of sampling cell systems. Moreover, experimentalists lack a set of quantitative guidelines that…

Quantitative Methods · Quantitative Biology 2017-12-18 Johan Markdahl , Nicolo Colombo , Johan Thunberg , Jorge Goncalves

Molecular profiling data (e.g., gene expression) has been used for clinical risk prediction and biomarker discovery. However, it is necessary to integrate other prior knowledge like biological pathways or gene interaction networks to…

Genomics · Quantitative Biology 2016-09-22 Wenwen Min , Juan Liu , Shihua Zhang

In information retrieval, training reranking models mainly focuses on two types of objectives: metric learning (e.g. contrastive loss to increase the predicted scores on relevant query-document pairs) and classification (binary label…

Computation and Language · Computer Science 2025-10-17 Ziqi Dai , Xin Zhang , Mingxin Li , Yanzhao Zhang , Dingkun Long , Pengjun Xie , Meishan Zhang , Wenjie Li , Min Zhang

Inferring chemical reaction networks (CRN) from concentration time series is a challenge encouragedby the growing availability of quantitative temporal data at the cellular level. This motivates thedesign of algorithms to infer the…

Quantitative Methods · Quantitative Biology 2023-02-09 Julien Martinelli , Jeremy Grignard , Sylvain Soliman , Annabelle Ballesta , François Fages

Dynamical properties of the transcriptional regulatory network of {\it Escherichia coli} and {\it Saccharomyces cerevisiae} are studied within the framework of random Boolean functions. The dynamical response of these networks to a single…

Molecular Networks · Quantitative Biology 2007-05-23 Deok-Sun Lee , Heiko Rieger

Large Language Models (LLMs) are susceptible to indirect prompt injection attacks, where the model inadvertently responds to instructions injected into the prompt context. This vulnerability stems from LLMs' inability to distinguish between…

Cryptography and Security · Computer Science 2026-05-12 Rui Wang , Junda Wu , Yu Xia , Tong Yu , Ruiyi Zhang , Ryan Rossi , Subrata Mitra , Lina Yao , Julian McAuley

Language models can use verifiable rewards to improve at a wide variety of reasoning tasks. However, both parametric (e.g. RLVR) and non-parametric (e.g. prompt optimization) approaches to doing so typically require hundreds of training…

Artificial Intelligence · Computer Science 2026-05-28 Linas Nasvytis , Simon Jerome Han , Ben Prystawski , Satchel Grant , Noah D. Goodman , Judith E. Fan

We propose a direct optimization framework for learning reduced and sparse chemical reaction networks (CRNs) from time-series trajectory data. In contrast to widely used indirect methods-such as those based on sparse identification of…

Molecular Networks · Quantitative Biology 2025-08-27 Maurice Filo , Mustafa Khammash

Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-protein interactions, etc. A common setting involves inferring network edges…

Quantitative Methods · Quantitative Biology 2007-05-23 Jean-Philippe Vert , Jian Qiu , William Stafford Noble

Gene regulatory networks (GRN) are being studied with increasingly precise quantitative tools and can provide a testing ground for ideas regarding the emergence and evolution of complex biological networks. We analyze the global statistical…

Molecular Networks · Quantitative Biology 2010-12-14 Berkin Malkoc , Duygu Balcan , Ayse Erzan

Large Language Models (LLMs) often rely on test-time scaling via parallel decoding (for example, 512 samples) to boost reasoning accuracy, but this incurs substantial compute. We introduce CoRefine, a confidence-guided self-refinement…

Artificial Intelligence · Computer Science 2026-02-10 Chen Jin , Ryutaro Tanno , Tom Diethe , Philip Teare

A connection between the General Linear Model (GLM) in combination with classical statistical inference and the machine learning (MLE)-based inference is described in this paper. Firstly, the estimation of the GLM parameters is expressed as…

Machine Learning · Statistics 2022-02-10 Juan Manuel Gorriz , SIPBA group , John Suckling

Biological networks are pivotal in deciphering the complexity and functionality of biological systems. Causal inference, which focuses on determining the directionality and strength of interactions between variables rather than merely…

Molecular Networks · Quantitative Biology 2025-11-05 Hongyang Jiang , Yuezhu Wang , Ke Feng , Chaoyi Yin , Yi Chang , Huiyan Sun

This work explores the potential utility of neural network classifiers for real-time classification of field-potential based biomarkers in next-generation responsive neuromodulation systems. Compared to classical filter-based classifiers,…

Signal Processing · Electrical Eng. & Systems 2023-01-16 Ali Kavoosi , Robert Toth , Moaad Benjaber , Mayela Zamora , Antonio Valentin , Andrew Sharott , Timothy Denison

In the context of cellular networks, users located at the periphery of cells are particularly vulnerable to substantial interference from neighbouring cells, which can be represented as a two-user interference channel. This study introduces…

Information Theory · Computer Science 2024-10-29 Shubham Paul , Sudharsan Senthil , Preethi Seshadri , Nambi Seshadri , R David Koilpillai

In recent years, machine learning (ML) based reconstruction has been widely investigated and employed in cardiac magnetic resonance (CMR) imaging. ML-based reconstructions can deliver clinically acceptable image quality under substantially…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Chi Zhang , Michael Loecher , Cagan Alkan , Mahmut Yurt , Shreyas S. Vasanawala , Daniel B. Ennis

The inference of gene regulatory networks from high throughput gene expression data is one of the major challenges in systems biology. This paper aims at analysing and comparing two different algorithmic approaches. The first approach uses…

Quantitative Methods · Quantitative Biology 2008-12-05 A. Braunstein , A. Pagnani , M. Weigt , R. Zecchina

Middle training methods aim to bridge the gap between the Masked Language Model (MLM) pre-training and the final finetuning for retrieval. Recent models such as CoCondenser, RetroMAE, and LexMAE argue that the MLM task is not sufficient…

Information Retrieval · Computer Science 2023-06-06 Hervé Déjean , Stéphane Clinchant , Carlos Lassance , Simon Lupart , Thibault Formal