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Single Particle Tracking (SPT) can aid in understanding complex spatio-temporal processes. However, quantifying diffusivity and forces from individual live cell trajectories is complicated by inter- & intra-trajectory kinetic heterogeneity,…

Quantitative Methods · Quantitative Biology 2016-05-19 Christopher P. Calderon

Likelihood-free methods are useful for parameter estimation of complex models with intractable likelihood functions for which it is easy to simulate data. Such models are prevalent in many disciplines including genetics, biology, ecology…

Methodology · Statistics 2022-03-29 Christopher Drovandi , David T Frazier

This article describes a multivariate polynomial regression method where the uncertainty of the input parameters are approximated with Gaussian distributions, derived from the central limit theorem for large weighted sums, directly from the…

Machine Learning · Statistics 2013-10-04 Peter Kovesarki , Ian C. Brock

In this paper, we propose a maximum smoothed likelihood method to estimate the component density functions of mixture models, in which the mixing proportions are known and may differ among observations. The proposed estimates maximize a…

Methodology · Statistics 2014-07-14 Tao Yu , Pengfei Li , Jing Qin

Maximum likelihood estimation is effective for identifying dynamical systems, but applying it to large networks becomes computationally prohibitive. This paper introduces a maximum likelihood estimation method that enables identification of…

Systems and Control · Electrical Eng. & Systems 2025-11-06 João Victor Galvão da Mata , Anders Hansson , Martin S. Andersen

In this paper, we describe an algorithm and associated software package (sfit_minimize) for maximizing the likelihood function of a set of parameters by minimizing $\chi^2$. The key element of this method is that the algorithm estimates the…

Instrumentation and Methods for Astrophysics · Physics 2025-02-10 Jennifer C. Yee , Andrew P. Gould

Maximum likelihood fits to data can be done using binned data (histograms) and unbinned data. With binned data, one gets not only the fitted parameters but also a measure of the goodness of fit. With unbinned data, currently, the fitted…

Data Analysis, Statistics and Probability · Physics 2014-11-18 Rajendran Raja

Many statistical models in cosmology can be simulated forwards but have intractable likelihood functions. Likelihood-free inference methods allow us to perform Bayesian inference from these models using only forward simulations, free from…

Cosmology and Nongalactic Astrophysics · Physics 2018-04-11 Justin Alsing , Benjamin Wandelt , Stephen Feeney

Usually, equal time is given to measuring the background and the sample, or even a longer background measurement is taken as it has so few counts. While this seems the right thing to do, the relative error after background subtraction…

Data Analysis, Statistics and Probability · Physics 2012-10-22 Brian Richard Pauw , Samuel Tardif

This study explores various data-driven methods for performing background-model selection, and for assigning uncertainty on the signal-strength estimator that arises due to the choice of background model. The performance of these methods is…

High Energy Physics - Experiment · Physics 2018-06-19 Mike Williams

LISA Pathfinder (LPF), ESA's precursor mission to a gravitational wave observatory, will measure the degree to which two test-masses can be put into free-fall, aiming to demonstrate a residual relative acceleration with a power spectral…

A suggestion is made for improving the Feldman Cousins method of estimating signal counts in the presence of background. The method concentrates on finding essential information about the signal and ignoring extraneous information about…

Data Analysis, Statistics and Probability · Physics 2009-10-31 Byron P. Roe , Michael B. Woodroofe

An exploit of the Sequential Importance Sampling (SIS) algorithm using Differential Algebra (DA) techniques is derived to develop an efficient particle filter. The filter creates an original kind of particles, called scout particles, that…

Information Theory · Computer Science 2024-08-21 Simone Servadio

Modern neural networks, although achieving state-of-the-art results on many tasks, tend to have a large number of parameters, which increases training time and resource usage. This problem can be alleviated by pruning. Existing methods,…

Machine Learning · Computer Science 2020-09-08 Andrei Apostol , Maarten Stol , Patrick Forré

Most parameter constraints obtained from cosmic microwave background (CMB) anisotropy data are based on power estimates and rely on approximate likelihood functions; computational difficulties generally preclude an exact analysis based on…

Astrophysics · Physics 2009-11-06 M. Douspis , J. G. Bartlett , A. Blanchard , M. Le Dour

In this article we propose an optimal method referred to as SPlit for splitting a dataset into training and testing sets. SPlit is based on the method of Support Points (SP), which was initially developed for finding the optimal…

Machine Learning · Statistics 2021-05-10 V. Roshan Joseph , Akhil Vakayil

Researchers frequently test and improve model fit by holding a sample constant and varying the model. We propose methods to test and improve sample fit by holding a model constant and varying the sample. Much as the bootstrap is a…

Econometrics · Economics 2022-09-15 Gabriel Okasa , Kenneth A. Younge

This work proposes a new loss function targeting classification problems, utilizing a source of information overlooked by cross entropy loss. First, we derive a series of the tightest upper and lower bounds for the probability of a random…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Ali Ghobadzadeh , Amir Lashkari

This article discusses the determination of asymmetries. We consider a sample of events consisting of a peak of signal events on top of some background events. Both signal and background have an unknown asymmetry, e.g. a spin or…

Data Analysis, Statistics and Probability · Physics 2009-05-20 Jörg Pretz , Jean-Marc Le Goff

The ratio between two probability density functions is an important component of various tasks, including selection bias correction, novelty detection and classification. Recently, several estimators of this ratio have been proposed. Most…

Methodology · Statistics 2014-04-30 Rafael Izbicki , Ann B. Lee , Chad M. Schafer