English
Related papers

Related papers: Regularized estimation of large-scale gene associa…

200 papers

Regularization has become a primary tool for developing reliable estimators of the covariance matrix in high-dimensional settings. To curb the curse of dimensionality, numerous methods assume that the population covariance (or inverse…

Methodology · Statistics 2018-02-19 Jacob Bien

Gaussian graphical models are widely used to represent correlations among entities but remain vulnerable to data corruption. In this work, we introduce a modified trimmed-inner-product algorithm to robustly estimate the covariance in an…

Machine Learning · Computer Science 2023-09-19 Tong Yao , Shreyas Sundaram

One of the fundamental tasks of science is to find explainable relationships between observed phenomena. One approach to this task that has received attention in recent years is based on probabilistic graphical modelling with sparsity…

Machine Learning · Statistics 2014-04-16 Peter Orchard , Felix Agakov , Amos Storkey

Over the past decade, various methods have been proposed for the reconstruction of networks modeled as Gaussian Graphical Models. In this work, we analyzed three different approaches: the Graphical Lasso (GLasso), the Graphical Ridge…

Applications · Statistics 2019-05-06 Henrique Bolfarine , Lina Thomas , Anatoly Yambartsev

Sparse graphical modelling has attained widespread attention across various academic fields. We propose two new graphical model approaches, Gslope and Tslope, which provide sparse estimates of the precision matrix by penalizing its sorted…

Gaussian Graphical Models (GGM) are often used to describe the conditional correlations between the components of a random vector. In this article, we compare two families of GGM inference methods: nodewise edge selection and penalised…

Reconstructing gene regulatory networks from large-scale heterogeneous data is a key challenge in biology. In multi-omics data analysis, networks based on pairwise statistical association measures remain popular, as they are easy to build…

Methodology · Statistics 2025-06-11 Ekaterina Tomilina , Florence Jaffrézic , Gildas Mazo

Applications on inference of biological networks have raised a strong interest in the problem of graph estimation in high-dimensional Gaussian graphical models. To handle this problem, we propose a two-stage procedure which first builds a…

Statistics Theory · Mathematics 2012-02-17 Christophe Giraud , Sylvie Huet , Nicolas Verzelen

The partial correlation graphical LASSO (PCGLASSO) is a penalised likelihood method for Gaussian graphical models which provides scale invariant sparse estimation of the precision matrix and improves upon the popular graphical LASSO method.…

Methodology · Statistics 2025-10-30 Jack Storror Carter , Cesare Molinari

3D Gaussian Splatting (3DGS) has demonstrated impressive novel view synthesis performance. While conventional methods require per-scene optimization, more recently several feed-forward methods have been proposed to generate pixel-aligned…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Shengjun Zhang , Xin Fei , Fangfu Liu , Haixu Song , Yueqi Duan

Graphical models, used to express conditional dependence between random variables observed at various nodes, are used extensively in many fields such as genetics, neuroscience, and social network analysis. While most current statistical…

Methodology · Statistics 2022-10-25 Jiajing Niu , Boyoung Hur , John Absher , D. Andrew Brown

Gaussian processes are a flexible Bayesian nonparametric modelling approach that has been widely applied but poses computational challenges. To address the poor scaling of exact inference methods, approximation methods based on sparse…

Machine Learning · Statistics 2021-06-01 Rui Meng , Herbert Lee , Soper Braden , Priyadip Ray

Gaussian Graphical Models (GGMs) have wide-ranging applications in machine learning and the natural and social sciences. In most of the settings in which they are applied, the number of observed samples is much smaller than the dimension…

Machine Learning · Computer Science 2020-03-10 Jonathan Kelner , Frederic Koehler , Raghu Meka , Ankur Moitra

Inferring a graphical model or network from observational data from a large number of variables is a well studied problem in machine learning and computational statistics. In this paper we consider a version of this problem that is relevant…

Methodology · Statistics 2013-12-06 Andy Dahl , Victoria Hore , Valentina Iotchkova , Jonathan Marchini

We consider the problem of estimating a sparse precision matrix of a multivariate Gaussian distribution, including the case where the dimension $p$ is large. Gaussian graphical models provide an important tool in describing conditional…

Statistics Theory · Mathematics 2014-04-08 Sayantan Banerjee , Subhashis Ghosal

Modern technologies are producing a wealth of data with complex structures. For instance, in two-dimensional digital imaging, flow cytometry, and electroencephalography, matrix type covariates frequently arise when measurements are obtained…

Methodology · Statistics 2013-10-22 Hua Zhou , Lexin Li

Graphical LASSO (GLASSO) is a widely used method for estimating sparse precision matrices and learning undirected graphical models in high-dimensional settings. Because GLASSO penalizes entries of the precision matrix directly, however, it…

Statistics Theory · Mathematics 2026-05-11 Małgorzata Bogdan , Adam Chojecki , Ivan Hejný , Bartosz Kołodziejek , Jonas Wallin

Sparse estimation for Gaussian graphical models is a crucial technique for making the relationships among numerous observed variables more interpretable and quantifiable. Various methods have been proposed, including graphical lasso, which…

Machine Learning · Computer Science 2024-08-09 Tomokaze Shiratori , Yuichi Takano

In genome-wide prediction, independence of marker allele substitution effects is typically assumed; however, since early stages of this technology it has been known that nature points to correlated effects. In statistics, graphical models…

Quantitative Methods · Quantitative Biology 2017-09-21 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

We present a deterministic method to compute the Gaussian average of neural networks used in regression and classification. Our method is based on an equivalence between training with a particular regularized loss, and the expected values…

Machine Learning · Computer Science 2020-06-12 Ryan Campbell , Chris Finlay , Adam M Oberman