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Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation. In this paper, we are interested in…

Probability · Mathematics 2016-11-28 Charline Smadi

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

The colonization of unoccupied territory by invading species, known as range expansion, is a spatially heterogeneous non-equilibrium growth process. We introduce a two-species Eden growth model to analyze the interplay between…

Statistical Mechanics · Physics 2011-11-15 Jan-Timm Kuhr , Madeleine Leisner , Erwin Frey

Genetic interactions can strongly influence the fitness effects of individual mutations, yet the impact of these epistatic interactions on evolutionary dynamics remains poorly understood. Here we investigate the evolutionary role of…

Populations and Evolution · Quantitative Biology 2014-11-14 Benjamin H. Good , Michael M. Desai

Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of asexual organisms is coupled to molecular properties and…

Populations and Evolution · Quantitative Biology 2009-11-13 Muyoung Heo , Louis Kang , Eugene I. Shakhnovich

We analyze the population dynamics of a broad class of fitness functions that exhibit epochal evolution---a dynamical behavior, commonly observed in both natural and artificial evolutionary processes, in which long periods of stasis in an…

adap-org · Physics 2007-05-23 James P. Crutchfield , Erik van Nimwegen

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

Probability · Mathematics 2021-09-14 Aurélien Velleret

Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

Populations and Evolution · Quantitative Biology 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

We study the effect of spatial structure, genetic drift, mutation, and selective pressure on the evolutionary dynamics in a simplified model of asexual organisms colonizing a new territory. Under an appropriate coarse-graining, the…

Statistical Mechanics · Physics 2013-01-15 Maxim O. Lavrentovich , Kirill S. Korolev , David R. Nelson

In ecology and population dynamics, gene-flow refers to the transfer of a trait from one population to another. This phenomenon appears in studying the evolution of social features, such as languages. From the mathematical point of view,…

Optimization and Control · Mathematics 2021-10-22 Idriss Mazari , Domenec Ruiz-Balet , Enrique Zuazua

Population dynamics on a rugged landscape is studied analytically and numerically within a simple discrete model for evolution of N individuals in one-dimensional fitness space. We reduce the set of master equations to a single Fokker-Plank…

adap-org · Physics 2015-06-30 Igor Aranson , Lev Tsimring , Valerii Vinokur

Source-sink systems are metapopulations of habitat patches with different, and possibly temporally varying, habitat qualities, which are commonly used in ecology to study the fate of spatially extended natural populations. We propose new…

Probability · Mathematics 2012-10-18 Vincent Bansaye , Amaury Lambert

It is widely accepted that population genetics theory is the cornerstone of evolutionary analyses. Empirical tests of the theory, however, are challenging because of the complex relationships between space, dispersal, and evolution.…

Populations and Evolution · Quantitative Biology 2011-10-26 Kirill S. Korolev , Joao B. Xavier , David R. Nelson , Kevin R. Foster

Geographic structure can affect patterns of genetic differentiation and speciation rates. In this article, we investigate the dynamics of genetic distances in a geographically structured metapopulation. We model the metapopulation as a…

Populations and Evolution · Quantitative Biology 2020-02-25 Verónica Miró Pina , Emmanuel Schertzer

We examine the switching dynamics of a stochastic population subjected to a deterministically time-varying environment. Our approach is demonstrated in the realm of ecology on a problem of population establishment. Here, by assuming a…

Statistical Mechanics · Physics 2020-02-19 Tom Israeli , Michael Assaf

Natural microbial populations often have complex spatial structures. This can impact their evolution, in particular the ability of mutants to take over. While mutant fixation probabilities are known to be unaffected by sufficiently…

Populations and Evolution · Quantitative Biology 2024-12-30 Alia Abbara , Anne-Florence Bitbol

It is generally accepted that populations are useful for the global exploration of multi-modal optimisation problems. Indeed, several theoretical results are available showing such advantages over single-trajectory search heuristics. In…

Neural and Evolutionary Computing · Computer Science 2019-03-27 Dogan Corus , Pietro S. Oliveto

Natural selection drives populations towards higher fitness, but crossing fitness valleys or plateaus may facilitate progress up a rugged fitness landscape involving epistasis. We investigate quantitatively the effect of subdividing an…

Populations and Evolution · Quantitative Biology 2014-08-18 Anne-Florence Bitbol , David J. Schwab

Population structure induced by both spatial embedding and more general networks of interaction, such as model social networks, have been shown to have a fundamental effect on the dynamics and outcome of evolutionary games. These effects…

Populations and Evolution · Quantitative Biology 2009-11-13 Gergely J Szollosi , Imre Derenyi

The Fleming-Viot measure-valued diffusion is a Markov process describing the evolution of (allelic) types under mutation, selection and random reproduction. We enrich this process by genealogical relations of individuals so that the random…

Probability · Mathematics 2012-11-30 Andrej Depperschmidt , Andreas Greven , Peter Pfaffelhuber