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The effects of chaotic advection and diffusion on fast chemical reactions in two-dimensional fluid flows are investigated using experimentally measured stretching fields and fluorescent monitoring of the local concentration. Flow symmetry,…

Fluid Dynamics · Physics 2009-11-13 P. E. Arratia , J. P. Gollub

Complex systems are often characterized by the interplay of multiple interconnected dynamical processes operating across a range of temporal scales. This phenomenon is widespread in both biological and artificial scenarios, making it…

Statistical Mechanics · Physics 2025-09-08 Giorgio Nicoletti , Daniel M. Busiello

Based on the theory of stochastic chemical kinetics, the inherent randomness and stochasticity of biochemical reaction networks can be accurately described by discrete-state continuous-time Markov chains. The analysis of such processes is,…

Numerical Analysis · Mathematics 2014-10-14 Andreychenko Alexander , Mikeev Linar , Wolf Verena

Controlling complex dynamical systems has been a topic of considerable interest in academic circles in recent decades. While existing works have primarily focused on closed-loop control schemes with infinite-time durations, this paper…

Optimization and Control · Mathematics 2025-01-08 Xiaoxiao Peng , Shijie Zhou

The process of fluctuations of trajectory observables of stochastic systems is related to processes with independent increments from the risk theory. The first-passage times of variables of the thermodynamics of trajectories, in particular,…

Statistical Mechanics · Physics 2025-06-17 V. V. Ryazanov

Stochastic thermodynamics as reviewed here systematically provides a framework for extending the notions of classical thermodynamics like work, heat and entropy production to the level of individual trajectories of well-defined…

Statistical Mechanics · Physics 2015-06-05 Udo Seifert

We present the stochastic thermodynamics analysis of an open quantum system weakly coupled to multiple reservoirs and driven by a rapidly oscillating external field. The analysis is built on a modified stochastic master equation in the…

Statistical Mechanics · Physics 2015-05-12 Gregory Bulnes Cuetara , Andreas Engel , Massimiliano Esposito

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

Probability · Mathematics 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston

Motion of particles (bodies) in presence of random effects can be considered stochastic process. However, application of widely known stochastic processes used for description of particle motion is reduced to relatively small class of…

General Physics · Physics 2022-04-14 Jiri Prochazka

The intrinsic stochasticity of gene expression can give rise to large fluctuations and rare events that drive phenotypic variation in a population of genetically identical cells. Characterizing the fluctuations that give rise to such rare…

Statistical Mechanics · Physics 2017-05-24 Jordan M. Horowitz , Rahul V. Kulkarni

We introduce the framework of performative control, where the policy chosen by the controller affects the underlying dynamics of the control system. This results in a sequence of policy-dependent system state data with policy-dependent…

Optimization and Control · Mathematics 2024-10-31 Songfu Cai , Fei Han , Xuanyu Cao

The effects of intrinsic noise on stochastic delay systems is studied within an expansion in the inverse system size. We show that the stochastic nature of the underlying dynamics may induce oscillatory behaviour in parameter ranges where…

Molecular Networks · Quantitative Biology 2015-05-13 Tobias Galla

The number of molecules involved in a cell or subcellular structure is sometimes rather small. In this situation, ordinary macroscopic-level fluctuations can be overwhelmed by non-negligible large fluctuations, which results in drastic…

Molecular Networks · Quantitative Biology 2016-11-15 Nen Saito , Yuki Sughiyama , Kunihiko Kaneko

Flux analysis is a class of constraint-based approaches to the study of biochemical reaction networks: they are based on determining the reaction flux configurations compatible with given stoichiometric and thermodynamic constraints. One of…

Molecular Networks · Quantitative Biology 2015-05-18 A. De Martino , E. Marinari

We consider stochastic models of chemical reaction networks with time dependent input rates and several types of molecules. We prove that, in despite of strong time dependence of input rates, there is a kind of homeostasis phenomenon: far…

Mathematical Physics · Physics 2012-01-18 V. A. Malyshev , A. D. Manita , A. A. Zamyatin

We consider the fluctuations of a time-integrated particle current around an atypical value in a generic stochastic Markov process involving classical particles with two-site interaction and hardcore repulsion on a finite one-dimensional…

Statistical Mechanics · Physics 2016-01-20 Pegah Torkaman , Farhad H. Jafarpour

According to the chemical reaction network theory, the topology of a certain class of chemical reaction networks, regardless of the kinetic details, sets a limit on the dynamical properties that a particular network can potentially admit;…

Molecular Networks · Quantitative Biology 2014-08-21 Jaewook Joo , Sanjeev Chauhan

We utilize the externally forced linearized Navier-Stokes equations to study the receptivity of pre-transitional boundary layers to persistent sources of stochastic excitation. Stochastic forcing is used to model the effect of free-stream…

Fluid Dynamics · Physics 2019-09-09 Wei Ran , Armin Zare , M. J. Philipp Hack , Mihailo R. Jovanović

This paper investigates the robustness of stochastic optimal control for controlled regime switching diffusions. We consider systems driven by both continuous fluctuations and discrete regime changes, allowing for model misspecification in…

Optimization and Control · Mathematics 2025-11-24 Somnath Pradhan , Dinesh Rathia