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To provide the Cytoscape users the possibility of integrating ITM Probe into their workflows, we developed CytoITMprobe, a new Cytoscape plugin. CytoITMprobe maintains all the desirable features of ITM Probe and adds additional flexibility…

Quantitative Methods · Quantitative Biology 2012-03-21 Aleksandar Stojmirović , Alexander Bliskovsky , Yi-Kuo Yu

Motivation: In the last few years a growing interest in biology has been shifting towards the problem of optimal information extraction from the huge amount of data generated via large scale and high-throughput techniques. One of the most…

Quantitative Methods · Quantitative Biology 2007-05-23 M. Leone , A. Pagnani

Life depends as much on the flow of information as on the flow of energy. Here we review the many efforts to make this intuition precise. Starting with the building blocks of information theory, we explore examples where it has been…

Quantitative Methods · Quantitative Biology 2014-12-31 Gašper Tkačik , William Bialek

This paper introduces a new macroscopic perspective for simulating transportation networks. The idea is to look at the network as connected nodes. Each node sends an information package to its neighbors. Basically, the information package…

Dynamical Systems · Mathematics 2024-07-19 Omar Mansour , Tomer Toledo , Shadi Haj-Yahia , Wafa Elias

Interaction networks, consisting of agents linked by their interactions, are ubiquitous across many disciplines of modern science. Many methods of analysis of interaction networks have been proposed, mainly concentrating on node degree…

Molecular Networks · Quantitative Biology 2011-12-20 Aleksandar Stojmirović , Yi-Kuo Yu

The embedded topic model (ETM) is a widely used approach that assumes the sampled document-topic distribution conforms to the logistic normal distribution for easier optimization. However, this assumption oversimplifies the real…

Computation and Language · Computer Science 2025-01-03 Wei Shao , Mingyang Liu , Linqi Song

In the theoretical modelling of a physical system a crucial step consists in the identification of those degrees of freedom that enable a synthetic, yet informative representation of it. While in some cases this selection can be carried out…

Statistical Mechanics · Physics 2020-06-30 Marco Giulini , Roberto Menichetti , M. Scott Shell , Raffaello Potestio

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

Computational Engineering, Finance, and Science · Computer Science 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li

Online social networks have become an important platform for people to communicate, share knowledge and disseminate information. Given the widespread usage of social media, individuals' ideas, preferences and behavior are often influenced…

Social and Information Networks · Computer Science 2023-09-12 Hui Li , Susu Yang , Mengting Xu , Sourav S Bhowmick , Jiangtao Cui

Influence maximization is the task of selecting a small number of seed nodes in a social network to maximize the influence spread from these seeds. It has been widely investigated in the past two decades. In the canonical setting, the…

Social and Information Networks · Computer Science 2022-02-21 Zhijie Zhang , Wei Chen , Xiaoming Sun , Jialin Zhang

Information diffusion and virus propagation are fundamental processes taking place in networks. While it is often possible to directly observe when nodes become infected with a virus or adopt the information, observing individual…

Data Structures and Algorithms · Computer Science 2015-03-17 Manuel Gomez-Rodriguez , Jure Leskovec , Andreas Krause

In a feedforward network, Transfer Entropy (TE) can be used to measure the influence that one layer has on another by quantifying the information transfer between them during training. According to the Information Bottleneck principle, a…

Machine Learning · Computer Science 2024-04-03 Adrian Moldovan , Angel Cataron , Razvan Andonie

Summary: The development of automated servers to predict the three-dimensional structure of proteins has seen much progress over the years. These servers make modeling simpler, but largely exclude users from the process. We present an…

Biomolecules · Quantitative Biology 2017-02-08 Rowan Hatherley , David K. Brown , Özlem Tastan Bishop

Inference of the network structure (e.g., routing topology) and dynamics (e.g., link performance) is an essential component in many network design and management tasks. In this paper we propose a new, general framework for analyzing and…

Networking and Internet Architecture · Computer Science 2019-11-13 Jian Ni , Sekhar Tatikonda

Textual network embedding leverages rich text information associated with the network to learn low-dimensional vectorial representations of vertices. Rather than using typical natural language processing (NLP) approaches, recent research…

Computation and Language · Computer Science 2019-01-15 Xinyuan Zhang , Yitong Li , Dinghan Shen , Lawrence Carin

Due to network operation and maintenance relying heavily on network traffic monitoring, traffic matrix analysis has been one of the most crucial issues for network management related tasks. However, it is challenging to reliably obtain the…

Networking and Internet Architecture · Computer Science 2024-12-02 Xinyu Yuan , Yan Qiao , Zhenchun Wei , Zeyu Zhang , Minyue Li , Pei Zhao , Rongyao Hu , Wenjing Li

Transcriptomic data is a treasure-trove in modern molecular biology, as it offers a comprehensive viewpoint into the intricate nuances of gene expression dynamics underlying biological systems. This genetic information must be utilised to…

Molecular Networks · Quantitative Biology 2023-12-13 Vikram Singh , Vikram Singh

This paper provides an elementary, self-contained analysis of diffusion-based sampling methods for generative modeling. In contrast to existing approaches that rely on continuous-time processes and then discretize, our treatment works…

Machine Learning · Statistics 2025-06-25 Galen Reeves , Henry D. Pfister

The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases. The RFM has been used to model…

Networking and Internet Architecture · Computer Science 2015-08-26 Yoram Zarai , Oz Mendel , Michael Margaliot

Understanding how large language models (LLMs) represent natural language is a central challenge in natural language processing (NLP) research. Many existing methods extract word embeddings from an LLM, visualise the embedding space via…

Computation and Language · Computer Science 2026-01-12 Thomas Fabian
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