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Related papers: Comments on "Remeasuring the Double Helix"

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DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

Recent experiments [J. van Mameren et al. PNAS 106, 18231 (2009)] provide a detailed spatial picture of overstretched DNA, showing that under certain conditions the two strands of the double helix separate at about 65 pN. It was proposed…

Soft Condensed Matter · Physics 2011-03-14 Stephen Whitelam , Phillip L. Geissler , Sander Pronk

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2008-02-03 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

When the DNA double helix is subjected to external forces it can stretch elastically to elongations reaching 100% of its natural length. These distortions, imposed at the mesoscopic or macroscopic scales, have a dramatic effect on…

Materials Science · Physics 2009-11-13 Ryan Barnett , Paul Maragakis , Ari Turner , Maria Fyta , Efthimios Kaxiras

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2009-10-28 Randall D. Kamien , Tom C. Lubensky , Philip Nelson , Corey S. O'Hern

A promising new method for measuring intramolecular distances in solution uses small-angle X-ray scattering interference between gold nanocrystal labels (Mathew-Fenn et al, Science, 322, 446 (2008)). When applied to double stranded DNA, it…

Biomolecules · Quantitative Biology 2015-05-13 Alexey K. Mazur

We investigate the effects excluded volume on the stretching of a single DNA in solution. We find that for small force F, the extension h is not linear in F but proportion to F^{\chi}, with \chi=(1-\nu)/\nu, where \nu is the well-known…

Statistical Mechanics · Physics 2007-05-23 Pui-Man Lam

For short DNA molecules in crowded environments, we evaluate macroscopic parameters such as the average end-to-end distance and the twist conformation by tuning the strength of the site specific confinement driven by the crowders. The…

Soft Condensed Matter · Physics 2019-06-14 Marco Zoli

The experiment that the high spin selectivity and the length-dependent spin polarization are observed in double-stranded DNA [Science ${\bf 331}$, 894 (2011)], is elucidated by considering the combination of the spin-orbit coupling, the…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ai-Min Guo , Qing-feng Sun

Plectonemes are intertwined helically looped domains which form when a DNA molecule is supercoiled, i.e. over- or under-wounded. They are ubiquitous in cellular DNA and their physical properties have attracted significant interest both from…

Soft Condensed Matter · Physics 2022-09-14 Enrico Skoruppa , Enrico Carlon

We predict various detectable mechanical responses to the presence of local DNA defects which are defined as short DNA segments exhibiting mechanical properties obviously different from the 50 nm persistence length based semiflexible…

Biomolecules · Quantitative Biology 2009-05-04 Hu Chen , Jie Yan

Comment on "Fluctuations in the DNA double helix: A critical review" by Frank-Kamenetskii and Prakash

Statistical Mechanics · Physics 2015-05-26 Michel Peyrard , Thierry Dauxois

Double-stranded DNA `overstretches' at a pulling force of about 65 pN, increasing in length by a factor of 1.7. The nature of the overstretched state is unknown, despite its considerable importance for DNA's biological function and…

Statistical Mechanics · Physics 2009-11-13 Stephen Whitelam , Sander Pronk , Phillip L. Geissler

Extreme deformations of the DNA double helix attracted a lot of attention during the past decades. Particularly, the determination of the persistence length of DNA with extreme local disruptions, or kinks, has become a crucial problem in…

Biological Physics · Physics 2018-10-30 Kyryło A. Simonov

The chiral nature of DNA plays a crucial role in cellular processes. Here we use magnetic tweezers to explore one of the signatures of this chirality, the coupling between stretch and twist deformations. We show that the extension of a…

Biomolecules · Quantitative Biology 2009-09-29 Timothee Lionnet , Sylvain Joubaud , Richard Lavery , David Bensimon , Vincent Croquette

Although mechanical properties of DNA are well characterized at the kilo base-pair range, a number of recent experiments have suggested that DNA is more flexible at shorter length scales, which correspond to the regime that is crucial for…

Biomolecules · Quantitative Biology 2015-06-11 Agnes Noy , Ramin Golestanian

The influence of decoherence and bonding on the linear conductance of single double-stranded DNA molecules is examined by fitting a phenomenological statistical model developed recently (EPJB {\bf 68}, 237 (2009)) to experimental results.…

Soft Condensed Matter · Physics 2010-09-30 M. Zilly , O. Ujsaghy , D. E. Wolf

The effect of electrostatic interactions on the stretching of DNA is investigated using a simple worm like chain model. In the limit of small force there are large conformational fluctuations which are treated using a self-consistent…

Soft Condensed Matter · Physics 2009-10-31 Namkyung Lee , D. Thirumalai

The extension of DNA confined to nanochannels has been studied intensively and in detail. Yet quantitative comparisons between experiments and model calculations are difficult because most theoretical predictions involve undetermined…

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