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Computed Tomography (CT) imaging is one of the most influential diagnostic methods. In clinical reconstruction, an effective energy is used instead of total X-ray spectrum. This approximation causes an accuracy decline. To increase the…

Emerging Technologies · Computer Science 2018-07-25 Neda Gholami , Mohammad Mahdi Dehshibi , Mahmood Fazlali , Antonio Rueda-Toicen , Hector Zenil , Andrew Adamatzky

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

Medical Physics · Physics 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

This research paper presents a novel approach to the prediction of hypoxia in brain tumors, using multi-parametric Magnetic Resonance Imaging (MRI). Hypoxia, a condition characterized by low oxygen levels, is a common feature of malignant…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Daniele Perlo , Georgia Kanli , Selma Boudissa , Olivier Keunen

Simulation of atomic resolution image formation in scanning transmission electron microscopy can require significant computation times using traditional methods. A recently developed method, termed plane-wave reciprocal-space interpolated…

Computational Physics · Physics 2017-07-07 Alan Pryor , Colin Ophus , Jianwei Miao

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

Medical Physics · Physics 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…

Robotics · Computer Science 2023-12-07 Junxiang Wang , Ti Wu , Iulian I. Iordachita , Peter Kazanzides

Purpose: To develop a radiomics filtering technique for characterizing spatial-encoded regional pulmonary ventilation information on lung CT. Methods: The lung volume was segmented on 46 CT images, and a 3D sliding window kernel was…

Medical Physics · Physics 2023-01-11 Zhenyu Yang , Kyle J Lafata , Xinru Chen , James Bowsher , Yushi Chang , Chunhao Wang , Fang-Fang Yin

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

Medical Physics · Physics 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…

Computer Vision and Pattern Recognition · Computer Science 2013-06-10 Ji Won Yoon

The aim of this study was to develop radiomic models using PET/CT radiomic features with different machine learning approaches for finding best predictive epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS)…

Four-dimensional (4D) wide coverage computed tomography (CT) is an effective imaging modality for measuring the mechanical function of the myocardium. However, repeated CT measurement across several heartbeats is still a concern. A…

Medical Physics · Physics 2024-03-14 Zhye Yin , Pengwei Wu , Ashish Manohar , Elliot R. McVeigh , Jed D. Pack

Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…

Quantitative Methods · Quantitative Biology 2014-05-28 Kevin J. Black , Jonathan M. Koller , Brad D. Miller

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-small cell lung cancer (NSCLC). While [$^{18}$F]FDG PET/CT is a standard tool for the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Fatih Aksu , Laura Ciuffetti , Francesco Di Feola , Filippo Ruffini , Giulia Romoli , Fabrizia Gelardi , Arturo Chiti , Valerio Guarrasi , Paolo Soda

This study evaluates remote Photopletismography (rPPG) algorithms, Spatial Subspace Rotation (2SR), Chrominance-based method (CHROM), Plane-Orthogonal-to-Skin (POS), and Principal Component Analysis (PCA), applied to selected…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Đorđe D. Nešković , Nadica Miljković

Imaging the bio-impedance distribution of the brain can provide initial diagnosis of acute stroke. This paper presents a compact and non-radiative tomographic modality, i.e. multi-frequency Electromagnetic Tomography (mfEMT), for the…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Yonggui Dong , Yunjie Yang

How the human brain adjusts fuel handling and its bioenergetic state during changing glucose levels remains difficult to assess noninvasively. In this study, we established an interleaved multinuclear 7 T MR spectroscopy protocol to track a…

Medical Physics · Physics 2026-03-11 Mark Widmaier , Brooke C. Matson , Uzay Emir , Janice J. Hwang

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan