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We study a mathematical model describing the dynamics of a pluripotent stem cell population involved in the blood production process in the bone marrow. This model is a differential equation with a time delay. The delay describes the cell…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

We analyze the asymptotic stability of a nonlinear system of two differential equations with delay describing the dynamics of blood cell production. This process takes place in the bone marrow where stem cells differentiate throughout…

Analysis of PDEs · Mathematics 2009-04-17 Fabien Crauste

We consider a delay differential equation that occurs in the study of chronic myelogenous leukemia. After shortly reminding some previous results concerning the stability of equilibrium solutions, we concentrate on the study of stability of…

Dynamical Systems · Mathematics 2010-03-23 Anca-Veronica Ion , Raluca-Mihaela Georgescu

The objective of this paper is to investigate the stability of limit cycles of a mathematical model with a distributed delay which describes the interaction between p53 and mdm2. Choosing the delay as a bifurcation parameter we study the…

Dynamical Systems · Mathematics 2007-05-23 M. Neamtu , D. Opris , R. F. Horhat

We study the two state model which describes the balance equation for carbon dioxide and oxygen. These are nonlinear parameter dependent and because of the transport delay in the respiratory control system, they are modeled with delay…

Dynamical Systems · Mathematics 2022-06-29 Nirjal Sapkota , Janos Turi

Logistic functions are good models of biological population growth. They are also popular in marketing in modelling demand-supply curves and in a different context, to chart the sales of new products over time. Delays being inherent in any…

Populations and Evolution · Quantitative Biology 2012-11-30 Milind M. Rao , K. L. Preetish

This paper investigates the stability properties of a nonlinear fractional differential equation with two discrete delays and a delay-dependent coefficient. Such equations arise in various biological and control systems where temporal…

Dynamical Systems · Mathematics 2026-03-12 Pragati Dutta , Sachin Bhalekar

We model intracellular regulatory dynamics with threshold-type state-dependent delay and investigate the effect of the state-dependent diffusion time. A general model which is an extension of the classic differential equation models with…

Dynamical Systems · Mathematics 2018-03-13 Qingwen Hu

In this paper, a mathematical model of pneumococcal pneumonia with time delays is proposed. The stability theory of delay differential equations is used to analyze the model. The results show that the disease-free equilibrium is…

Populations and Evolution · Quantitative Biology 2019-01-16 Fulgensia Kamugisha Mbabazi , Joseph Y. T. Mugisha , Mark Kimathi

The logistic equation has many applications and is used frequently in different fields, such as biology, medicine, and economics. In this paper, we study the stability of a single-species logistic model with a general distribution delay…

Dynamical Systems · Mathematics 2023-10-12 Isam Al-Darabsah

In this paper we study a model of HCV with mitotic proliferation, a saturation infection rate and a discrete intracellular delay: the delay corresponds to the time between infection of a infected target hepatocytes and production of new HCV…

Dynamical Systems · Mathematics 2014-03-13 E. Avila-Vales , N. Chan-Chí , G. García-Almeida , C. Vargas-De-León

The stability of functional differential equations under delayed feedback is investigated near a Hopf bifurcation. Necessary and sufficient conditions are derived for the stability of the equilibrium solution using averaging theory. The…

Classical Analysis and ODEs · Mathematics 2008-12-31 Fatihcan M. Atay

We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model. There are two monotone nonlinearities in the model: one…

Dynamical Systems · Mathematics 2025-04-29 Tomas Gedeon , Antony R. Humphries , Michael C. Mackey , Hans-Otto Walther , Zhao Wang

We investigate a diffusive, stage-structured epidemic model with the maturation delay and freely-moving delay. Choosing delays and diffusive rates as bifurcation parameters, the only possible way to destabilize the endemic equilibrium is…

Dynamical Systems · Mathematics 2018-05-25 Yanfei Du , Ben Niu , Junjie Wei

In this paper, we study the existence and the property of the Hopf bifurcation in the two-strategy replicator dynamics with distributed delays. In evolutionary games, we assume that a strategy would take an uncertain time delay to have a…

Systems and Control · Computer Science 2017-03-21 Nesrine Ben Khalifa , Rachid El Azouzi , Yezekael Hayel

Neural field models with transmission delay may be cast as abstract delay differential equations (DDE). The theory of dual semigroups (also called sun-star calculus) provides a natural framework for the analysis of a broad class of delay…

Dynamical Systems · Mathematics 2017-12-11 Stephan A. van Gils , Sebastiaan G. Janssens , Yuri A. Kuznetsov , Sid Visser

We study delay-independent stability in nonlinear models with a distributed delay which have a positive equilibrium. Such models frequently occur in population dynamics and other applications. In particular, we construct a relevant…

Dynamical Systems · Mathematics 2009-01-12 Elena Braverman , Sergey Zhukovskiy

We study the effects of time delayed linear and nonlinear feedbacks on the dynamics of a single Hopf bifurcation oscillator. Our numerical and analytic investigations reveal a host of complex temporal phenomena such as phase slips,…

chao-dyn · Physics 2009-10-31 D. V. Ramana Reddy , A. Sen , G. L. Johnston

This article proposes a non-autonomous mathematical model with delay for confrontation between two countries, and examines the stability of its equilibrium state. Our criteria for stability take into account the influence of the factor of…

Dynamical Systems · Mathematics 2026-05-14 Teresa Faria , Anatoliy A. Martynyuk

Linear scalar differential equations with distributed delays appear in the study of the local stability of nonlinear differential equations with feedback, which are common in biology and physics. Negative feedback loops tend to promote…

Dynamical Systems · Mathematics 2014-05-29 Samuel Bernard , Fabien Crauste
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