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We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

In the first step, a pre-trained model (YOLO) was used to detect all suspicious nod-ules. The YOLO model was re-trained using 397 CT images to detect the entire nodule in CT images. To maximize the sensitivity of the model, a confidence…

Medical Physics · Physics 2022-12-20 Yashar Ahmadyar Razlighi , Alireza Kamali-Asl , Hossein Arabi

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

We aimed to evaluate computer-aided diagnosis (CADx) system for lung nodule classification focusing on (i) usefulness of gradient tree boosting (XGBoost) and (ii) effectiveness of parameter optimization using Bayesian optimization (Tree…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Mizuho Nishio , Mitsuo Nishizawa , Osamu Sugiyama , Ryosuke Kojima , Masahiro Yakami , Tomohiro Kuroda , Kaori Togashi

Accurate classification of histological subtypes of non-small cell lung cancer (NSCLC) is essential in the era of precision medicine, yet current invasive techniques are not always feasible and may lead to clinical complications. This study…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Fatih Aksu , Fabrizia Gelardi , Arturo Chiti , Paolo Soda

Detection of pulmonary nodules by CT is used for screening lung cancer in early stages.omputer aided diagnosis (CAD) based on deep-learning method can identify the suspected areas of pulmonary nodules in CT images, thus improving the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Yang Liu , Yue-Jie Hou , Chen-Xin Qin , Xin-Hui Li , Si-Jing Li , Bin Wang , Chi-Chun Zhou

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Abdelbaki Souid , Mohamed Hamroun , Soufiene Ben Othman , Hedi Sakli , Naceur Abdelkarim

Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Steve Kommrusch , Louis-Noël Pouchet

Pathologies systematically induce morphological changes, thus providing a major but yet insufficiently quantified source of observables for diagnosis. The study develops a predictive model of the pathological states based on morphological…

Lung cancer is a severe menace to human health, due to which millions of people die because of late diagnoses of cancer; thus, it is vital to detect the disease as early as possible. The Computerized chest analysis Tomography of scan is…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Ahmed Saihood , Hossein Karshenas , AhmadReza Naghsh Nilchi

The limited sample size and insufficient diversity of lung nodule CT datasets severely restrict the performance and generalization ability of detection models. Existing methods generate images with insufficient diversity and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lu Cao , Xiquan He , Junying Zeng , Chaoyun Mai , Min Luo

Content-based retrieval supports a radiologist decision making process by presenting the doctor the most similar cases from the database containing both historical diagnosis and further disease development history. We present a deep…

Information Retrieval · Computer Science 2020-07-15 Ilia Kravets , Tal Heletz , Hayit Greenspan

Pulmonary nodule detection, false positive reduction and segmentation represent three of the most common tasks in the computeraided analysis of chest CT images. Methods have been proposed for eachtask with deep learning based methods…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Hao Tang , Chupeng Zhang , Xiaohui Xie

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

A number of studies on lung nodule classification lack clinical/biological interpretations of the features extracted by convolutional neural network (CNN). The methods like class activation mapping (CAM) and gradient-based CAM (Grad-CAM)…

Computer Vision and Pattern Recognition · Computer Science 2019-12-18 Yiming Lei , Yukun Tian , Hongming Shan , Junping Zhang , Ge Wang , Mannudeep Kalra

Background and Objective: In pulmonary nodule detection, the first stage, candidate detection, aims to detect suspicious pulmonary nodules. However, detected candidates include many false positives and thus in the following stage, false…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Hyunjun Eun , Daeyeong Kim , Chanho Jung , Changick Kim

Lung nodules suffer large variation in size and appearance in CT images. Nodules less than 10mm can easily lose information after down-sampling in convolutional neural networks, which results in low sensitivity. In this paper, a combination…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Benyuan Sun , Zhen Zhou , Fandong Zhang , Xiuli Li , Yizhou Wang

The integration of Internet of Things (IoT) technology in pulmonary nodule detection significantly enhances the intelligence and real-time capabilities of the detection system. Currently, lung nodule detection primarily focuses on the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Meng Wang , Zi Yang , Ruifeng Zhao , Yaoting Jiang
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