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In this paper, we investigate a system of two nonlinear partial differential equations, arising from a model of cellular proliferation which describes the production of blood cells in the bone marrow. Due to cellular replication, the two…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste

We analyse the asymptotic behaviour of a nonlinear mathematical model of cellular proliferation which describes the production of blood cells in the bone marrow. This model takes the form of a system of two maturity structured partial…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Laurent Pujo-Menjouet

This paper analyses a nonlinear age-maturity structured system which arises as a model of the blood cellular production in the bone marrow. The resulting model is a nonlinear first-order partial differential equation in which there is a…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste

We analyze the asymptotic stability of a nonlinear system of two differential equations with delay describing the dynamics of blood cell production. This process takes place in the bone marrow where stem cells differentiate throughout…

Analysis of PDEs · Mathematics 2009-04-17 Fabien Crauste

This paper is devoted to the analysis of a mathematical model of blood cells production in the bone marrow (hematopoiesis). The model is a system of two age-structured partial differential equations. Integrating these equations over the…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

The paper discusses linear fractional representations of parameter-dependent nonlinear systems with dynamics defined by real rational nonlinearities and a finite set of point delays. The global asymptotic stability is investigated via…

Dynamical Systems · Mathematics 2008-03-27 M. De la Sen

We study a mathematical model describing the dynamics of a pluripotent stem cell population involved in the blood production process in the bone marrow. This model is a differential equation with a time delay. The delay describes the cell…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

In this paper we investigate a structured population model with distributed delay. Our model incorporates two different types of nonlinearities. Specifically we assume that individual growth and mortality are affected by scramble…

Analysis of PDEs · Mathematics 2023-07-18 Dandan Hu , József Z. Farkas , Gang Huang

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

We study delay-independent stability in nonlinear models with a distributed delay which have a positive equilibrium. Such models frequently occur in population dynamics and other applications. In particular, we construct a relevant…

Dynamical Systems · Mathematics 2009-01-12 Elena Braverman , Sergey Zhukovskiy

In this paper we study a nonlinear size-structured population model with distributed delay in the recruitment. The delayed problem is reduced into an abstract initial value problem of an ordinary differential equation in the Banach space by…

Analysis of PDEs · Mathematics 2014-04-15 Meng Bai , Shihe Xu

In this work first we consider a physiologically structured population model with a distributed recruitment process. That is, our model allows newly recruited individuals to enter the population at all possible individual states, in…

Analysis of PDEs · Mathematics 2017-01-13 Àngel Calsina , Odo Diekmann , József Z. Farkas

Partial differential equations are a convenient way to describe reaction- advection-diffusion processes of signalling models. If only one cell type is present, and tissue dynamics can be neglected, the equations can be solved directly.…

Quantitative Methods · Quantitative Biology 2015-09-29 Simon Tanaka

This paper investigates the stability properties of a nonlinear fractional differential equation with two discrete delays and a delay-dependent coefficient. Such equations arise in various biological and control systems where temporal…

Dynamical Systems · Mathematics 2026-03-12 Pragati Dutta , Sachin Bhalekar

Multiple myeloma is a plasma cell cancer that leads to a dysregulated bone remodeling process. We present a partial differential equation model describing the dynamics of bone remodeling with the presence of myeloma tumor cells. The model…

Cell Behavior · Quantitative Biology 2015-11-18 Catherine E. Patterson , Bruce P. Ayati , Sarah A. Holstein

We introduce a delay nonlinear differential equation model which describes how fish are harvested. In our previous studies we investigated the persistence of that equation and existence of a periodic solution for this equation. Here we…

Dynamical Systems · Mathematics 2007-05-23 L. Berezansky , L. Idels

A cellular automata model that describes as limit cases of his parameters the spread of contagious diseases modeled by systems of ordinary or partial differential equations is developed. Periodic features of the behavior of human settlement…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Ricardo Mansilla , Jose L. Gutierrez

We investigate a partial differential equation model of a cancer cell population, which is structured with respect to age and telomere length of cells. We assume a continuous telomere length structure, which is applicable to the clonal…

Analysis of PDEs · Mathematics 2019-03-06 József Z. Farkas , Glenn F. Webb

Linear scalar differential equations with distributed delays appear in the study of the local stability of nonlinear differential equations with feedback, which are common in biology and physics. Negative feedback loops tend to promote…

Dynamical Systems · Mathematics 2014-05-29 Samuel Bernard , Fabien Crauste

We analyze a differential equation with a state-dependent delay that is implicitly defined via the solution of an ODE. The equation describes an established though little analyzed cell population model. Based on theoretical results of…

Classical Analysis and ODEs · Mathematics 2014-11-13 Philipp Getto , Marcus Waurick
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