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The interactive exploration of large and evolving datasets is challenging as relationships between underlying variables may not be fully understood. There may be hidden trends and patterns in the data that are worthy of further exploration…
Metric $k$-center clustering is a fundamental unsupervised learning primitive. Although widely used, this primitive is heavily affected by noise in the data, so that a more sensible variant seeks for the best solution that disregards a…
Clustering can be defined as the process of assembling objects into a number of groups whose elements are similar to each other in some manner. As a technique that is used in many domains, such as face clustering, plant categorization,…
Most existing ontology matching methods utilize the literal information to discover alignments. However, some literal information in ontologies may be opaque and some ontologies may not have sufficient literal information. In this paper,…
We give a new successor data structure which improves upon the index size of the P\v{a}tra\c{s}cu-Thorup data structures, reducing the index size from $O(n w^{4/5})$ bits to $O(n \log w)$ bits, with optimal probe complexity. Alternatively,…
Subspace clustering is an important unsupervised clustering approach. It is based on the assumption that the high-dimensional data points are approximately distributed around several low-dimensional linear subspaces. The majority of the…
Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…
Genetic algorithms are a class of heuristic search techniques that apply basic evolutionary operators in a computational setting. We have designed a fully parallel and distributed hardware/software implementation of the generalized…
Motivation: Public and private repositories of experimental data are growing to sizes that require dedicated methods for finding relevant data. To improve on the state of the art of keyword searches from annotations, methods for…
High-density DNA arrays, used to monitor gene expression at a genomic scale, have produced vast amounts of information which require the development of efficient computational methods to analyze them. The important first step is to extract…
The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…
Full-waveform inversion (FWI) is known as a seismic data processing method that achieves high-resolution imaging. In the inversion part of the method that brings high resolution in finding a convergence point in the model space, a local…
Propensity score (PS) weighting methods are often used in non-randomized studies to adjust for confounding and assess treatment effects. The most popular among them, the inverse probability weighting (IPW), assigns weights that are…
Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…
Generalization to out-of-distribution (OOD) data is a critical challenge in machine learning. Ensemble-based methods, like weight space ensembles that interpolate model parameters, have been shown to achieve superior OOD performance.…
Given the increasing complexity of omics datasets, a key challenge is not only improving classification performance but also enhancing the transparency and reliability of model decisions. Effective model performance and feature selection…
Feature selection from a large number of covariates (aka features) in a regression analysis remains a challenge in data science, especially in terms of its potential of scaling to ever-enlarging data and finding a group of scientifically…
Subspace clustering is an unsupervised clustering technique designed to cluster data that is supported on a union of linear subspaces, with each subspace defining a cluster with dimension lower than the ambient space. Many existing…
Ensemble methods are among the state-of-the-art predictive modeling approaches. Applied to modern big data, these methods often require a large number of sub-learners, where the complexity of each learner typically grows with the size of…
Quantitative Susceptibility Mapping (QSM) is a new phase-based technique for quantifying magnetic susceptibility. The existing QSM reconstruction methods generally require complicated pre-processing on high-quality phase data. In this work,…