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Recent years have seen rapid progress at the intersection between causality and machine learning. Motivated by scientific applications involving high-dimensional data, in particular in biomedicine, we propose a deep neural architecture for…

Machine Learning · Computer Science 2022-12-12 Kai Lagemann , Christian Lagemann , Bernd Taschler , Sach Mukherjee

Several interesting models for contingency tables are defined by a system of equality and inequality constraints on a suitable set of marginal log-linear parameters. After reviewing the most common difficulties which are intrinsic to order…

Statistics Theory · Mathematics 2014-01-09 Roberto Colombi , Antonio Forcina

We present a new approach for random sampling of contingency tables of any size and constraints based on a recently introduced $\textit{probabilistic divide-and-conquer}$ technique. A simple exact sampling algorithm is presented for…

Statistics Theory · Mathematics 2016-03-01 Stephen DeSalvo , James Y. Zhao

We consider a setting in which we have a treatment and a large number of covariates for a set of observations, and wish to model their relationship with an outcome of interest. We propose a simple method for modeling interactions between…

Methodology · Statistics 2012-12-14 Lu Tian , Ash Alizadeh , Andrew Gentles , Robert Tibshirani

We develop estimation for potentially high-dimensional additive structural equation models. A key component of our approach is to decouple order search among the variables from feature or edge selection in a directed acyclic graph encoding…

Methodology · Statistics 2014-12-02 Peter Bühlmann , Jonas Peters , Jan Ernest

Declarative modeling uses symbolic expressions to represent models. With such expressions one can formalize high-level mathematical computations on models that would be difficult or impossible to perform directly on a lower-level simulation…

Quantitative Methods · Quantitative Biology 2019-07-02 Eric Mjolsness

Multilevel or hierarchical data structures can occur in many areas of research, including economics, psychology, sociology, agriculture, medicine, and public health. Over the last 25 years, there has been increasing interest in developing…

Methodology · Statistics 2018-01-08 Bernet S. Kato , Carel F. W. Peeters

Graphical models are an important tool in exploring relationships between variables in complex, multivariate data. Methods for learning such graphical models are well developed in the case where all variables are either continuous or…

Machine Learning · Statistics 2024-02-15 Konstantin Göbler , Anne Miloschewski , Mathias Drton , Sach Mukherjee

Sparse latent multi-factor models have been used in many exploratory and predictive problems with high-dimensional multivariate observations. Because of concerns with identifiability, the latent factors are almost always assumed to be…

Applications · Statistics 2013-12-09 Vinicius Diniz Mayrink , Joseph Edward Lucas

The intratumor heterogeneity has been recognized to characterize cancer cells impairing the efficacy of cancer treatments. We here propose an extension of constraint-based modeling approach in order to simulate metabolism of cell…

Quantitative Methods · Quantitative Biology 2016-07-18 M. Di Filippo , C. Damiani , R. Colombo , D. Pescini , G. Mauri

A common problem in large-scale data analysis is to approximate a matrix using a combination of specifically sampled rows and columns, known as CUR decomposition. Unfortunately, in many real-world environments, the ability to sample…

Machine Learning · Statistics 2018-07-10 Urvashi Oswal , Swayambhoo Jain , Kevin S. Xu , Brian Eriksson

In many high-dimensional problems,polynomial-time algorithms fall short of achieving the statistical limits attainable without computational constraints. A powerful approach to probe the limits of polynomial-time algorithms is to study the…

Statistics Theory · Mathematics 2025-07-11 Bertrand Even , Christophe Giraud , Nicolas Verzelen

In categorical data analysis, several regression models have been proposed for hierarchically-structured response variables, e.g. the nested logit model. But they have been formally defined for only two or three levels in the hierarchy.…

Methodology · Statistics 2014-05-23 Jean Peyhardi , Catherine Trottier , Yann Guédon

Large language models (LLMs) are primarily designed to understand unstructured text. When directly applied to structured formats such as tabular data, they may struggle to discern inherent relationships and overlook critical patterns. While…

Machine Learning · Computer Science 2024-10-11 Natraj Raman , Sumitra Ganesh , Manuela Veloso

Massive data collection holds the promise of a better understanding of complex phenomena and, ultimately, better decisions. Representation learning has become a key driver of deep learning applications, as it allows learning latent spaces…

Machine Learning · Computer Science 2025-11-10 Caroline Uhler , Jiaqi Zhang

Factor modeling is an essential tool for exploring intrinsic dependence structures among high-dimensional random variables. Much progress has been made for estimating the covariance matrix from a high-dimensional factor model. However, the…

Statistics Theory · Mathematics 2016-10-26 Quefeng Li , Guang Cheng , Jianqing Fan , Yuyan Wang

A complex system is made up of many components with many interactions. So the design of systems such as simulation systems, cooperative systems or assistance systems includes a very accurate modelling of interactional and communicational…

Multiagent Systems · Computer Science 2012-01-19 Alain-Jérôme Fougères

The macroscopic behavior of the solution of a coupled system of partial differential equations arising in the modeling of reaction-diffusion processes in periodic porous media is analyzed. Our mathematical model can be used for studying…

Analysis of PDEs · Mathematics 2019-06-19 G. Cardone , C. Perugia , C. Timofte

Graphical models can represent a multivariate distribution in a convenient and accessible form as a graph. Causal models can be viewed as a special class of graphical models that not only represent the distribution of the observed system…

Methodology · Statistics 2017-06-29 Christina Heinze-Deml , Marloes H. Maathuis , Nicolai Meinshausen

We provide a comprehensive overview of latent Markov (LM) models for the analysis of longitudinal categorical data. The main assumption behind these models is that the response variables are conditionally independent given a latent process…

Statistics Theory · Mathematics 2010-03-16 F. Bartolucci , A. Farcomeni , F. Pennoni