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The network approach became a widely used tool to understand the behaviour of complex systems in the last decade. We start from a short description of structural rigidity theory. A detailed account on the combinatorial rigidity analysis of…

Biological Physics · Physics 2012-12-04 Merse E. Gaspar , Peter Csermely

This study investigates the prevalence and implications of nestedness within primate social networks, examining its relationship with cognitive and structural factors. We analysed data from 51 primate groups across 21 species, employing…

We introduce an approach to partitioning networks into communities that not only determines the best community structure, but also provides a range of characterization techniques to assess how significant that structure is. We study the…

Statistical Mechanics · Physics 2007-05-23 Claire P. Massen , Jonathan P. K. Doye

Protein-protein interactions (protein functionalities) are mediated by water, which compacts individual proteins and promotes close and temporarily stable large-area protein-protein interfaces. Proteins are peptide chains decorated by amino…

Soft Condensed Matter · Physics 2008-02-26 J. C. Phillips

A deep understanding of the dynamics of the human nervous system requires the simultaneous study of multiple spatiotemporal scales from the level of neurotransmitters up to the level of human cultures. This is likely impossible for…

Neurons and Cognition · Quantitative Biology 2023-01-24 William Sulis

We characterize the large-sample properties of network modularity in the presence of covariates, under a natural and flexible nonparametric null model. This provides for the first time an objective measure of whether or not a particular…

Statistics Theory · Mathematics 2016-03-04 Beate Franke , Patrick J. Wolfe

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. We propose methods to assess the…

Quantitative Methods · Quantitative Biology 2009-10-17 Soumen Roy , Vladimir Filkov

There has been a surge of interest in community detection in homogeneous single-relational networks which contain only one type of nodes and edges. However, many real-world systems are naturally described as heterogeneous multi-relational…

Social and Information Networks · Computer Science 2014-07-21 Xin Liu , Weichu Liu , Tsuyoshi Murata , Ken Wakita

Conformation of a protein (CorA) is examined in a matrix with mobile solute constituents as a function of solute-residue interaction strength (f) by a coarse-grained model with a Monte Carlo simulation. Solute particles are found to reach…

Biological Physics · Physics 2020-08-26 Warin Rangubpit , Sunan Kitjaruwankul , Pornthep Sompornpisut , R. B. Pandey

Biological networks have evolved to be highly functional within uncertain environments while remaining extremely adaptable. One of the main contributors to the robustness and evolvability of biological networks is believed to be their…

Molecular Networks · Quantitative Biology 2008-02-14 Arend Hintze , Christoph Adami

Network representations have been effectively employed to analyze complex systems across various areas and applications, leading to the development of network science as a core tool to study systems with multiple components and complex…

Neurons and Cognition · Quantitative Biology 2023-07-25 ItaloIvo Lima Dias Pinto , Javier Omar Garcia , Kanika Bansal

Many real-world networks, including nervous systems, exhibit meso-scale structure. This means that their elements can be grouped into meaningful sub-networks. In general, these sub-networks are unknown ahead of time and must be "discovered"…

Neurons and Cognition · Quantitative Biology 2020-11-16 Richard F. Betzel

In signal processing, exploring complex systems through network representations has become an area of growing interest. This study introduces the modularity graph, a new graph-based feature, to highlight the relationship across the graph…

Neurons and Cognition · Quantitative Biology 2024-10-23 Tiziana Cattai , Camilla Caporali , Marie-Constance Corsi , Stefania Colonnese

We have found that known community identification algorithms produce inconsistent communities when the node ordering changes at input. We propose two metrics to quantify the level of consistency across multiple runs of an algorithm:…

Physics and Society · Physics 2009-10-10 Haewoon Kwak , Young-Ho Eom , Yoonchan Choi , Hawoong Jeong , Sue Moon

Community detection, which focuses on clustering nodes or detecting communities in (mostly) a single network, is a problem of considerable practical interest and has received a great deal of attention in the research community. While being…

Machine Learning · Statistics 2017-11-07 Soumendu Sundar Mukherjee , Purnamrita Sarkar , Lizhen Lin

Clustering and community structure is crucial for many network systems and the related dynamic processes. It has been shown that communities are usually overlapping and hierarchical. However, previous methods investigate these two…

Computers and Society · Computer Science 2009-02-20 Huawei Shen , Xueqi Cheng , Kai Cai , Mao-Bin Hu

The growing interest for comparing protein internal dynamics owes much to the realization that protein function can be accompanied or assisted by structural fluctuations and conformational changes. Analogously to the case of functional…

Biomolecules · Quantitative Biology 2012-12-19 C. Micheletti

We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate…

Molecular Networks · Quantitative Biology 2015-01-07 Jack Peterson , Steve Presse , Kristin S. Peterson , Ken A. Dill

Community structure is an important property of complex networks. An automatic discovery of such structure is a fundamental task in many disciplines, including sociology, biology, engineering, and computer science. Recently, several…

Physics and Society · Physics 2008-04-11 Jianhua Ruan , Weixiong Zhang

Modular structure is ubiquitous in real-world complex networks, and its detection is important because it gives insights in the structure-functionality Modular structure is ubiquitous in real-world complex networks, and its detection is…

Data Analysis, Statistics and Probability · Physics 2008-05-29 Alex Arenas , Alberto Fernandez , Sergio Gomez