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Related papers: Structure Transition in PSS/Lysozyme Complexes: A …

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Employing X-ray photon correlation spectroscopy we measure the kinetics and dynamics of a pressure-induced liquid-liquid phase separation (LLPS) in a water-lysozyme solution. Scattering invariants and kinetic information provide evidence…

Soft Condensed Matter · Physics 2021-07-13 M. Moron , A. Al-Masoodi , C. Lovato , M. Reiser , L. Randolph , G. Surmeier , J. Bolle , F. Westermeier , M. Sprung , R. Winter , M. Paulus , C. Gutt

Understanding the evolution of level densities in the crossover from spherical to well-deformed nuclei has been a long-standing problem in nuclear physics. We measure nuclear level densities for a chain of neodymium isotopes…

Pattern formation in drying protein droplets continues to attract considerable research attention because it can be linked to specific protein-protein interactions. An extensive study of the drying evolution and the final crack patterns are…

Soft Condensed Matter · Physics 2020-04-14 Anusuya Pal , Amalesh Gope , Ari S. Athair , Germano S. Iannacchione

We study the dynamics of hydration water/protein association in folded proteins, using lysozyme and myoglobin as examples. Extensive molecular dynamics simulations are performed to identify underlying mechanisms of the dynamical transition…

Soft Condensed Matter · Physics 2015-05-13 J. Servantie , C. Atilgan , A. R. Atilgan

The influence of structural constraints on the relaxation dynamics of three polyurea networks with varying degree of crosslinking, has been studied by means of a thorough analysis of broadband dielectric spectroscopy measurements. Two…

Soft Condensed Matter · Physics 2018-10-03 Nerea Sebastián , Christophe Contal , Antoni Sánchez-Ferrer , Marco Pieruccini

Studying protein interactions at low temperatures has important implications for optimizing cryostorage processes of biological tissue, food, and protein-based drugs. One of the major challenges is related to the formation of ice…

Pressure provides a powerful parameter to control the protein conformation state, which at sufficiently high values can lead to unfolding. Here, we investigate the effects of increasing pressure up to $0.4$ GPa on hydrated lysozyme…

S-nitrosylation, the covalent addition of NO to the thiol side chain of cysteine, is an important post-transitional modification that can alter the function of various proteins. The structural dynamics and vibrational spectroscopy of…

Chemical Physics · Physics 2020-12-01 Haydar Taylan Turan , Markus Meuwly

Combining elastic incoherent neutron scattering experiments at different resolutions with molecular dynamics simulations, we report the observation of a protein-like dynamical transition in linear chains of Poly(N-isopropylacrylamide). We…

Soft Condensed Matter · Physics 2021-03-11 L. Tavagnacco , M. Zanatta , E. Buratti , B. Rosi , B. Frick , F. Natali , J. Ollivier , E. Chiessi , M. Bertoldo , E. Zaccarelli , A. Orecchini

Single molecule experiments on B-DNA stretching have revealed one or two structural transitions, when increasing the external force. They are characterized by a sudden increase of DNA contour length and a decrease of the bending rigidity.…

Soft Condensed Matter · Physics 2012-10-25 Manoel Manghi , Nicolas Destainville , John Palmeri

The thermal decay of linear chains from a metastable state is investigated. A crossover from rigid to elastic decay occurs when the number of particles, the single particle energy barrier or the coupling strength between the particles is…

Superconductivity · Physics 2009-10-31 Thorsten Droese , Cristiane Morais-Smith

We numerically examine the properties of a two-dimensional system of particles which have competing long range repulsive and short range attractive interactions as a function of density and temperature. For increasing density, there are…

Soft Condensed Matter · Physics 2015-05-18 C. J. Olson Reichhardt , C. Reichhardt , A. R. Bishop

We introduce a new quantity to probe the glass transition. This quantity is a linear generalized compressibility which depends solely on the positions of the particles. We have performed a molecular dynamics simulation on a glass forming…

Disordered Systems and Neural Networks · Physics 2009-11-07 Herve M. Carruzzo , Clare C. Yu

The possibilities to tune the structure of solid like material resulting from arrested spinodal decomposition is investigated using a system composed of lysozyme, a globular protein, dispersed in a water solution as model system for…

Concentrated aqueous solutions of the protein lysozyme undergo a liquid solid transition upon a temperature quench into the unstable spinodal region below a characteristic arrest temperature of Tf=15C. We use video microscopy and…

Soft Condensed Matter · Physics 2015-05-13 Thomas Gibaud , Peter Schurtenberger

Various studies have shown that food structure has an impact on digestion kinetics. We focus here on the effects of gastric and intestinal enzymes (in-vitro digestion) on two canola seed storage proteins, napin and cruciferin. To monitor…

Post-transductional modifications tune the functions of proteins and regulate the collective dynamics of biochemical networks that determine how cells respond to environmental signals. For example, protein phosphorylation and nitrosylation…

Cell Behavior · Quantitative Biology 2009-11-13 Roberto Chignola , Chiara Dalla Pellegrina , Alessio Del Fabbro , Edoardo Milotti

We study the two-step spin crossover in a double-layered elastic model based on transition metal complexes each taking high spin (HS) and low spin (LS) states. Here, only the simplest elastic interactions between adjacent molecules are…

Materials Science · Physics 2017-11-15 Daisuke Taniguchi , Jun Okabayashi , Chisa Hotta

The evolution of the polymer structure during nanocomposite formation and annealing of silica-latex nanocomposites is studied using contrast-variation small angle neutron scattering. The experimental system is made of silica nanoparticles…

Small angle X-ray scattering (SAXS) studies in poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) with varying conjugation, and polyethylene dioxythiophene complexed with polystyrene sulfonate (PEDOT-PSS) in different…

Soft Condensed Matter · Physics 2010-11-11 Paramita Kar Choudhury , Debjani Bagchi , C. S. Suchand Sangeeth , Reghu Menon