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Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

Machine learning has the potential to fuel further advances in data science, but it is greatly hindered by an ad hoc design process, poor data hygiene, and a lack of statistical rigor in model evaluation. Recently, these issues have begun…

Machine Learning · Computer Science 2021-08-19 Stella Biderman , Walter J. Scheirer

Scaling analysis exploiting timescale separation has been one of the most important techniques in the quantitative analysis of nonlinear dynamical systems in mathematical and theoretical biology. In the case of enzyme catalyzed reactions,…

Quantitative Methods · Quantitative Biology 2023-03-21 Justin Eilertsen , Wylie Stroberg , Santiago Schnell

A dynamic model for failures in biological organisms is proposed and studied both analytically and numerically. Each cell in the organism becomes dead under sufficiently strong stress, and is then allowed to be healed with some probability.…

Cell Behavior · Quantitative Biology 2009-11-11 J. Choi , M. Y. Choi , B. -G. Yoon

When statisticians quarrel about hypothesis testing, the debate usually focus on which method is the correct one. The fundamental question of whether we should test hypothesis at all tends to be forgotten. This lack of debate has its roots…

Other Statistics · Statistics 2016-11-22 André C. R. Martins

Machine learning is currently involved in some of the most vigorous debates it has ever seen. Such debates often seem to go around in circles, reaching no conclusion or resolution. This is perhaps unsurprising given that researchers in…

Computers and Society · Computer Science 2020-04-13 Jessica Hamrick , Shakir Mohamed

Parallel application I/O performance often does not meet user expectations. Additionally, slight access pattern modifications may lead to significant changes in performance due to complex interactions between hardware and software. These…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-19 Julian M. Kunkel , Eugen Betke , Matt Bryson , Philip Carns , Rosemary Francis , Wolfgang Frings , Roland Laifer , Sandra Mendez

This article introduces a fully automated verification technique that permits to analyze real-time systems described using a continuous notion of time and a mixture of operational (i.e., automata-based) and descriptive (i.e., logic-based)…

Logic in Computer Science · Computer Science 2013-08-14 Carlo A. Furia , Matteo Pradella , Matteo Rossi

As machine learning systems become more powerful they also become increasingly unpredictable and opaque. Yet, finding human-understandable explanations of how they work is essential for their safe deployment. This technical report…

Designing a static analysis is generally a substantial undertaking, requiring significant expertise in both program analysis and the domain of the program analysis, and significant development resources. As a result, most program analyses…

Programming Languages · Computer Science 2018-10-17 Colin S. Gordon

Average-case analysis computes the complexity of an algorithm averaged over all possible inputs. Compared to worst-case analysis, it is more representative of the typical behavior of an algorithm, but remains largely unexplored in…

Optimization and Control · Mathematics 2021-10-05 Courtney Paquette , Bart van Merriënboer , Elliot Paquette , Fabian Pedregosa

The methods are proposed for evaluation of complex dynamical systems, choice of their optimal operating modes, determination of optimal operating system from given class of equivalent systems, system's timeline behaviour analysis on the…

Optimization and Control · Mathematics 2016-03-04 Dmytro Polishchuk , Olexandr Polishchuk

Although the halting problem is undecidable, imperfect testers that fail on some instances are possible. Such instances are called hard for the tester. One variant of imperfect testers replies "I don't know" on hard instances, another…

Logic in Computer Science · Computer Science 2014-12-01 Antti Valmari

Explainability and comprehensibility of AI are important requirements for intelligent systems deployed in real-world domains. Users want and frequently need to understand how decisions impacting them are made. Similarly it is important to…

Computers and Society · Computer Science 2019-07-10 Roman V. Yampolskiy

This paper presents a taxonomy of explainability in Human-Agent Systems. We consider fundamental questions about the Why, Who, What, When and How of explainability. First, we define explainability, and its relationship to the related terms…

Artificial Intelligence · Computer Science 2019-04-18 Avi Rosenfeld , Ariella Richardson

This paper focuses on the mathematical approaches to the analysis of stability that is a crucial step in the design of dynamical systems. Three methods are presented, namely, absolutely integrable impulse response, Fourier integral, and…

Systems and Control · Electrical Eng. & Systems 2020-01-06 Kamyar Modjtahedzadeh

Notifications provide a unique mechanism for increasing the effectiveness of real-time information delivery systems. However, notifications that demand users' attention at inopportune moments are more likely to have adverse effects and…

Human-Computer Interaction · Computer Science 2018-01-03 Abhinav Mehrotra , Mirco Musolesi

Inspired by the work of Tsiamis et al. \cite{tsiamis2022learning}, in this paper we study the statistical hardness of learning to stabilize linear time-invariant systems. Hardness is measured by the number of samples required to achieve a…

Systems and Control · Electrical Eng. & Systems 2023-11-21 Xiong Zeng , Zexiang Liu , Zhe Du , Necmiye Ozay , Mario Sznaier

This paper takes a look at the general characteristics of business or economic intelligence system. The role of the user within this type of system is emphasized. We propose two models which we consider important in order to adapt this…

Information Retrieval · Computer Science 2007-05-23 Babajide Afolabi , Odile Thiery

Explainability is a critical factor in enhancing the trustworthiness and acceptance of artificial intelligence (AI) in healthcare, where decisions directly impact patient outcomes. Despite advancements in AI interpretability, clear…

Artificial Intelligence · Computer Science 2025-05-15 Michail Mamalakis , Héloïse de Vareilles , Graham Murray , Pietro Lio , John Suckling