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Related papers: Reconstructing Spatiotemporal Gene Expression Data…

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Motivation: Gene regulatory interactions are of fundamental importance to various biological functions and processes. However, only a few previous computational studies have claimed success in revealing genome-wide regulatory landscapes…

Molecular Networks · Quantitative Biology 2017-02-09 Shupeng Gui , Rui Chen , Liang Wu , Ji Liu , Hongyu Miao

High-fidelity simulation of complex physical systems is exorbitantly expensive and inaccessible across spatiotemporal scales. Recently, there has been an increasing interest in leveraging deep learning to augment scientific data based on…

Machine Learning · Computer Science 2022-08-03 Pu Ren , Chengping Rao , Yang Liu , Zihan Ma , Qi Wang , Jian-Xun Wang , Hao Sun

In agriculture, the majority of vision systems perform still image classification. Yet, recent work has highlighted the potential of spatial and temporal cues as a rich source of information to improve the classification performance. In…

Robotics · Computer Science 2022-06-28 Claus Smitt , Michael Halstead , Alireza Ahmadi , Chris McCool

Accurate predictions and representations of plant growth patterns in simulated and controlled environments are important for addressing various challenges in plant phenomics research. This review explores various works on state-of-the-art…

Quantitative Methods · Quantitative Biology 2025-07-17 Mohamed Debbagh , Shangpeng Sun , Mark Lefsrud

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interrogate how spatially localised gene expression can lend new…

Quantitative Methods · Quantitative Biology 2021-08-04 Natalie Charitakis , Mirana Ramialison , Hieu T. Nim

Identifying genes that display spatial patterns is critical to investigating expression interactions within a spatial context and further dissecting biological understanding of complex mechanistic functionality. Despite the increase in…

Methodology · Statistics 2025-10-06 Mingcong Wu , Yang Li , Shuangge Ma , Mengyun Wu

Motivation: Inferring the structure of gene regulatory networks from high--throughput datasets remains an important and unsolved problem. Current methods are hampered by problems such as noise, low sample size, and incomplete…

Quantitative Methods · Quantitative Biology 2017-12-04 Phan Nguyen , Rosemary Braun

Spatiotemporal graph represents a crucial data structure where the nodes and edges are embedded in a geometric space and can evolve dynamically over time. Nowadays, spatiotemporal graph data is becoming increasingly popular and important,…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Hengning Cao , Yanfang Ye , Liang Zhao

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Quantitative modeling of post-transcriptional regulation process is a challenging problem in systems biology. A mechanical model of the regulatory process needs to be able to describe the available spatio-temporal protein concentration and…

Machine Learning · Statistics 2016-10-18 Mu Niu , Zhenwen Dai , Neil Lawrence , Kolja Becker

Hyper-spectral data can be analyzed to recover physical properties at large planetary scales. This involves resolving inverse problems which can be addressed within machine learning, with the advantage that, once a relationship between…

Applications · Statistics 2015-12-31 Antoine Deleforge , Florence Forbes , Sileye Ba , Radu Horaud

Compositional data, such as regional shares of economic sectors or property transactions, are central to understanding structural change in economic systems across space and time. This paper introduces a spatiotemporal multivariate…

Applications · Statistics 2026-03-16 Matthias Eckardt , Philipp Otto

This paper presents a novel approach for representing proprioceptive time-series data from quadruped robots as structured two-dimensional images, enabling the use of convolutional neural networks for learning locomotion-related tasks. The…

To understand dynamic developmental processes, living tissues must be imaged frequently and for extended periods of time. Root development is extensively studied at cellular resolution to understand basic mechanisms underlying pattern…

Tissues and Organs · Quantitative Biology 2015-03-13 Giovanni Sena , Zak Frentz , Kenneth D. Birnbaum , Stanislas Leibler

This paper concerns the data-driven sensor deployment problem in large spatiotemporal fields. Traditionally, sensor deployment strategies have been heavily dependent on model-based planning approaches. However, model-based approaches do not…

Signal Processing · Electrical Eng. & Systems 2022-01-04 Jiahong Chen

Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…

Genomics · Quantitative Biology 2024-08-02 Boyi Guo , Wodan Ling , Sang Ho Kwon , Pratibha Panwar , Shila Ghazanfar , Keri Martinowich , Stephanie C. Hicks

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Spatial transcriptomics aims to connect high-resolution histology images with spatially resolved gene expression. To achieve better performance on downstream tasks such as gene expression prediction, large-scale pre-training is required to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Jiahe Qian , Yaoyu Fang , Ziqiao Weng , Xinkun Wang , Lee A. Cooper , Bo Zhou

The rapid growth of earth observation systems calls for a scalable approach to interpolate remote-sensing observations. These methods in principle, should acquire more information about the observed field as data grows. Gaussian processes…

Machine Learning · Computer Science 2024-12-17 Weibin Chen , Azhir Mahmood , Michel Tsamados , So Takao