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Related papers: PICS: Probabilistic Inference for ChIP-seq

200 papers

Accurate identification of haplotypes in sequenced human genomes can provide invaluable information about population demography and fine-scale correlations along the genome, thus empowering both population genomic and medical association…

Genomics · Quantitative Biology 2012-11-12 Fouad Zakharia , Carlos Bustamante

Accurate prediction of protein-ligand binding affinity is crucial for rapid and efficient drug development. Recently, the importance of predicting binding affinity has led to increased attention on research that models the three-dimensional…

Machine Learning · Computer Science 2024-07-17 Seungyeon Choi , Sangmin Seo , Sanghyun Park

Existing Referring Image Segmentation (RIS) methods typically require expensive pixel-level or box-level annotations for supervision. In this paper, we observe that the referring texts used in RIS already provide sufficient information to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Fang Liu , Yuhao Liu , Yuqiu Kong , Ke Xu , Lihe Zhang , Baocai Yin , Gerhard Hancke , Rynson Lau

A central problem in hyperspectral image classification is obtaining high classification accuracy when using a limited amount of labelled data. In this paper we present a novel graph-based framework, which aims to tackle this problem in the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Philip Sellars , Angelica Aviles-Rivero , Carola-Bibiane Schönlieb

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

As a fundamental visual attribute, image complexity significantly influences both human perception and the performance of computer vision models. However, accurately assessing and quantifying image complexity remains a challenging task. (1)…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Shipeng Liu , Liang Zhao , Dengfeng Chen

Visual segmentation is a key perceptual function that partitions visual space and allows for detection, recognition and discrimination of objects in complex environments. The processes underlying human segmentation of natural images are…

Computer Vision and Pattern Recognition · Computer Science 2019-05-03 Jonathan Vacher , Pascal Mamassian , Ruben Coen-Cagli

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Topological features such as persistence diagrams and their functional approximations like persistence images (PIs) have been showing substantial promise for machine learning and computer vision applications. This is greatly attributed to…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Anirudh Som , Hongjun Choi , Karthikeyan Natesan Ramamurthy , Matthew Buman , Pavan Turaga

RNA-Seq technology allows for studying the transcriptional state of the cell at an unprecedented level of detail. Beyond quantification of whole-gene expression, it is now possible to disentangle the abundance of individual alternatively…

Genomics · Quantitative Biology 2012-10-11 Barbara Rakitsch , Christoph Lippert , Hande Topa , Karsten Borgwardt , Antti Honkela , Oliver Stegle

Recent text-to-image (T2I) generators can synthesize realistic images, but still struggle with compositional prompts involving multiple objects, counts, attributes, and relations. We introduce EPIC (Efficient Predicate-Guided Inference-Time…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Sunung Mun , Sunghyun Cho , Jungseul Ok

Mass spectrometry provides a high-throughput approach to identify proteins in biological samples. A key step in the analysis of mass spectrometry data is to identify the peptide sequence that, most probably, gave rise to each observed…

Applications · Statistics 2013-01-14 Qunhua Li , Jimmy K. Eng , Matthew Stephens

Coupled partial differential equations underpin a wide range of multiphysics systems, yet existing neural PDE solvers still struggle to resolve localized high-risk regions and often fail to preserve structural admissibility across coupled…

Computational Physics · Physics 2026-03-31 Ze Tao , Hongfu Zhou , Hanbing Liang , Fujun Liu

Referring Image Segmentation (RIS) is a cross-modal task that aims to segment an instance described by a natural language expression. Recent methods leverage large-scale pretrained unimodal models as backbones along with fusion techniques…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Seoyeon Kim , Minguk Kang , Dongwon Kim , Jaesik Park , Suha Kwak

Tiling arrays make possible a large scale exploration of the genome thanks to probes which cover the whole genome with very high density until 2 000 000 probes. Biological questions usually addressed are either the expression difference…

Beyond the success of Contrastive Language-Image Pre-training (CLIP), recent trends mark a shift toward exploring the applicability of lightweight vision-language models for resource-constrained scenarios. These models often deliver…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Chu Myaet Thwal , Ye Lin Tun , Minh N. H. Nguyen , Eui-Nam Huh , Choong Seon Hong

We developed a method for estimating the positional distribution of transcription fac-tor (TF) binding sites using ChIP-chip data, and applied it to recently published experiments on binding sites of nine TFs; OCT4, SOX2, NANOG, HNF1A,…

Molecular Networks · Quantitative Biology 2008-11-11 Mark Koudritsky , Eytan Domany

Splice sites play a crucial role in gene expression, and accurate prediction of these sites in DNA sequences is essential for diagnosing and treating genetic disorders. We address the challenge of splice site prediction by introducing…

Genomics · Quantitative Biology 2023-11-23 Asmita Poddar , Vladimir Uzun , Elizabeth Tunbridge , Wilfried Haerty , Alejo Nevado-Holgado

Genome sequencing technology has improved significantly in few last years and resulted in abundance genetic data. Artificial intelligence has been employed to analyze genetic data in response to its sheer size and variability. Gene…

Genomics · Quantitative Biology 2023-03-17 Muhammad Anwari Leksono , Ayu Purwarianti

Class-incremental/Continual image segmentation (CIS) aims to train an image segmenter in stages, where the set of available categories differs at each stage. To leverage the built-in objectness of query-based transformers, which mitigates…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Yuchen Zhu , Cheng Shi , Dingyou Wang , Jiajin Tang , Zhengxuan Wei , Yu Wu , Guanbin Li , Sibei Yang