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Gene expression microarray technologies provide the simultaneous measurements of a large number of genes. Typical analyses of such data focus on the individual genes, but recent work has demonstrated that evaluating changes in expression…

Applications · Statistics 2010-06-29 Babak Shahbaba , Robert Tibshirani , Catherine M. Shachaf , Sylvia K. Plevritis

Many statistical problems involve optimization over a discrete parameter space having an unknown dimension. In such settings, gradient-based methods often fail due to the non-differentiability of the objective function or a non-convex or…

Applications · Statistics 2026-03-19 Mo Li , QiQi Lu , Robert Lund , Xueheng Shi

We propose a new method, called a deep-genetic algorithm (deep-GA), to accelerate the performance of the so-called deep-BSDE method, which is a deep learning algorithm to solve high dimensional partial differential equations through their…

A series of results of evolution supervised by genetic algorithms with interest to agricultural and horticultural fields are reviewed. New obtained original results from the use of genetic algorithms on structure-activity relationships are…

Neural and Evolutionary Computing · Computer Science 2010-09-07 Lorentz Jäntschi , Sorana D. Bolboac{\ba} , Mugur C. Bălan , Radu E. Sestraş

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Xueli Xiao , Ming Yan , Sunitha Basodi , Chunyan Ji , Yi Pan

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

We describe a genetic algorithm to find extreme examples in the arithmetic of dynamical systems. The algorithm is applied to four problems: small (non-zero) canonical heights, many rational preperiodic points, long rational cycles, and long…

Dynamical Systems · Mathematics 2026-05-06 Benjamin Hutz

Gene Regulatory Networks (GRNs) are intricate biological systems that control gene expression and regulation in response to environmental and developmental cues. Advances in computational biology, coupled with high throughput sequencing…

Machine Learning · Computer Science 2025-04-18 Akshata Hegde , Tom Nguyen , Jianlin Cheng

Mathematical modeling is a powerful tool for describing, predicting, and understanding complex phenomena exhibited by real-world systems. However, identifying the equations that govern a system's dynamics from experimental data remains a…

Neural and Evolutionary Computing · Computer Science 2024-12-05 Omar Rodríguez-Abreo , José Luis Aragón , Mario Alan Quiroz-Juárez

A random-key genetic algorithm is an evolutionary metaheuristic for discrete and global optimization. Each solution is encoded as a vector of N random keys, where a random key is a real number randomly generated in the continuous interval…

Neural and Evolutionary Computing · Computer Science 2026-01-13 Mariana A. Londe , Luciana S. Pessoa , Carlos E. Andrade , José F. Gonçalves , Mauricio G. C. Resende

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

Coverage of image features play an important role in many vision algorithms since their distribution affect the estimated homography. This paper presents a Genetic Algorithm (GA) in order to select the optimal set of features yielding…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Erkan Bostanci

The rapid advances in the field of optimization methods in many pure and applied science pose the difficulty of keeping track of the developments as well as selecting an appropriate technique that best suits the problem in-hand. From a…

Neural and Evolutionary Computing · Computer Science 2011-12-30 Loris Serafino

In this paper we demonstrate how genetic algorithms can be used to reverse engineer an evaluation function's parameters for computer chess. Our results show that using an appropriate mentor, we can evolve a program that is on par with top…

Neural and Evolutionary Computing · Computer Science 2017-11-21 Eli David , Moshe Koppel , Nathan S. Netanyahu

State selective field ionization detection techniques in physics require a specific progression through a complicated atomic state space to optimize state selectivity and overall efficiency. For large principle quantum number n, the…

Instrumentation and Detectors · Physics 2010-10-28 M. L. Jones , B. Sanguinetti , H. O. Majeed , B. T. H. Varcoe

The standard Lambda cold dark matter ($\Lambda$CDM) paradigm of the physical Universe suffers from well-known conceptual problems and is challenged by observational data. Alternative models exist in the literature, both phenomenological and…

Cosmology and Nongalactic Astrophysics · Physics 2026-05-13 D. Castelão , I. Tereno

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

It is very challenging to select informative features from tens of thousands of measured features in high-throughput data analysis. Recently, several parametric/regression models have been developed utilizing the gene network information to…

Applications · Statistics 2014-08-01 Yize Zhao , Jian Kang , Tianwei Yu

We recently reported that the simple genetic algorithm (SGA) is capable of performing a remarkable form of sublinear computation which has a straightforward connection with the general problem of interacting attributes in data-mining. In…

Neural and Evolutionary Computing · Computer Science 2009-05-18 Keki M. Burjorjee

Machine learning provides a broad framework for addressing high-dimensional prediction problems in classification and regression. While machine learning is often applied for imaging problems in medical physics, there are many efforts to…

Applications · Statistics 2020-07-02 John Kang , James T. Coates , Robert L. Strawderman , Barry S. Rosenstein , Sarah L. Kerns