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Algorithms proposed for solving high-dimensional optimization problems with no derivative information frequently encounter the "curse of dimensionality," becoming ineffective as the dimension of the parameter space grows. One feature of a…

Optimization and Control · Mathematics 2020-04-28 Dmitry Pozharskiy , Noah J. Wichrowski , Andrew B. Duncan , Grigorios A. Pavliotis , Ioannis G. Kevrekidis

In large-scale excitatory neuronal networks, rapid synchronization manifests as {multiple firing events (MFEs)}, mathematically characterized by a finite-time blow-up of the neuronal firing rate in the mean-field Fokker-Planck equation.…

Numerical Analysis · Mathematics 2026-03-23 Xu'an Dou , Louis Tao , Zhe Xue , Zhennan Zhou

We study a neural network model of interacting stochastic discrete two--state cellular automata on a regular lattice. The system is externally tuned to a critical point which varies with the degree of stochasticity (or the effective…

Statistical Mechanics · Physics 2015-06-12 Kaustubh Manchanda , Avinash Chand Yadav , Ramakrishna Ramaswamy

We propose a data-driven, coarse-graining formulation in the context of equilibrium statistical mechanics. In contrast to existing techniques which are based on a fine-to-coarse map, we adopt the opposite strategy by prescribing a…

Machine Learning · Statistics 2017-02-01 Markus Schöberl , Nicholas Zabaras , Phaedon-Stelios Koutsourelakis

Mean-field theory is a powerful tool for studying large neural networks. However, when the system is composed of a few neurons, macroscopic differences between the mean-field approximation and the real behavior of the network can arise.…

Neurons and Cognition · Quantitative Biology 2016-09-28 Diego Fasoli , Anna Cattani , Stefano Panzeri

Graphical models are widely used to make inferences concerning interplay in multivariate systems. In many applications, data are collected from multiple related but nonidentical units whose underlying networks may differ but are likely to…

Methodology · Statistics 2014-12-04 Chris J. Oates , Jim Korkola , Joe W. Gray , Sach Mukherjee

We present a computer-assisted approach to locating approximate coarse optimal switching policies between stationary states of chemically reacting systems described by microscopic/stochastic evolution rules. The ``coarse time-stepper"…

Optimization and Control · Mathematics 2007-05-23 Antonios Armaou , Ioannis G. Kevrekidis

Algebraic multigrid (AMG) methods derive their optimal efficiency from the interplay between a relaxation process and a corresponding coarse grid correction. In many standard formulations, relaxation and coarse-graining are analyzed and…

Numerical Analysis · Mathematics 2026-03-30 Rayan Moussa , Karsten Kahl

Euler's elastica is a classical model of flexible slender structures, relevant in many industrial applications. Static equilibrium equations can be derived via a variational principle. The accurate approximation of solutions of this problem…

Dynamic graphs are rife with higher-order interactions, such as co-authorship relationships and protein-protein interactions in biological networks, that naturally arise between more than two nodes at once. In spite of the ubiquitous…

Machine Learning · Computer Science 2021-02-09 Manohar Kaul , Masaaki Imaizumi

We analyze large systems of interacting proteins, using techniques from the non-equilibrium statistical mechanics of disordered many-particle systems. Apart from protein production and removal, the most relevant microscopic processes in the…

Molecular Networks · Quantitative Biology 2015-05-14 A. C. C. Coolen , S. Rabello

Particles interacting with short-ranged potentials have attracted increasing interest, partly for their ability to model mesoscale systems such as colloids interacting via DNA or depletion. We consider the free energy landscape of such…

Mathematical Physics · Physics 2015-06-11 Miranda Holmes-Cerfon , Steven J. Gortler , Michael P. Brenner

Molecular dynamics are extremely complex, yet understanding the slow components of their dynamics is essential to understanding their macroscopic properties. To achieve this, one models the molecular dynamics as a stochastic process and…

Chemical Physics · Physics 2020-11-17 Luca Donati , Marcus Weber , Bettina G. Keller

Our understanding of a variety of phenomena in physics, biology and economics crucially depends on the analysis of multivariate time series. While a wide range of tools and techniques for time series analysis already exist, the increasing…

Physics and Society · Physics 2015-10-27 Lucas Lacasa , Vincenzo Nicosia , Vito Latora

The `equation-free toolbox' empowers the computer-assisted analysis of complex, multiscale systems. Its aim is to enable you to immediately use microscopic simulators to perform macro-scale system level tasks and analysis, because…

Mathematical Software · Computer Science 2020-04-08 John Maclean , J. E. Bunder , A. J. Roberts

In past decades, enormous effort has been expended to develop algorithms and even to construct special-purpose computers in order to efficiently evaluate total energies and forces for long-range-interacting particle systems, with the…

Statistical Mechanics · Physics 2024-10-14 Gabriele Tartero , Werner Krauth

Active Brownian particles (ABPs) function as self-driving agents that display non-equilibrium behavior through their pairwise interactions which lead to phase separation and vortex patterns in both soft matter and living systems. A…

Soft Condensed Matter · Physics 2025-09-09 Sadra Saremi , Amirhossein Ahmadkhan Kordbacheh

In this work we introduce a new class of gradient-free global optimization methods based on a binary interaction dynamics governed by a Boltzmann type equation. In each interaction the particles act taking into account both the best…

Optimization and Control · Mathematics 2022-06-09 Alessandro Benfenati , Giacomo Borghi , Lorenzo Pareschi

We present a promising coarse-graining strategy for linking micro- and mesoscales of soft matter systems. The approach is based on effective pairwise interaction potentials obtained from detailed atomistic molecular dynamics (MD)…

Soft Condensed Matter · Physics 2007-05-23 A. P. Lyubartsev , M. Karttunen , I. Vattulainen , A. Laaksonen

This work deals with the investigation of bifurcating fluid phenomena using a reduced order modelling setting aided by artificial neural networks. We discuss the POD-NN approach dealing with non-smooth solutions set of nonlinear…

Fluid Dynamics · Physics 2023-08-08 Federico Pichi , Francesco Ballarin , Gianluigi Rozza , Jan S. Hesthaven
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