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Related papers: Nucleocytoplasmic transport: a thermodynamic mecha…

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A polymer chain confined in nano-scale geometry has been used to investigate the underlying mechanism of Nuclear Pore Complex (NPC), where transport of cargoes is directional. It was shown here that depending on the solvent quality (good or…

Soft Condensed Matter · Physics 2017-08-02 Sanjay Kumar , Sanjiv Kumar , Debaprasad Giri , Shesh Nath

The nucleon spectral function in infinite nuclear matter is calculated in a quantum transport theoretical approach. Exploiting the known relation between collision rates and correlation functions the spectral function is derived…

Nuclear Theory · Physics 2009-11-06 J. Lehr , M. Effenberger , H. Lenske , S. Leupold , U. Mosel

We couple two-dimensional hydrodynamics to realistic one-dimensional multigroup flux-limited diffusion neutrino transport to investigate protoneutron star convection in core collapse supernovae, and more specifically, the interplay between…

The mechanisms controlling the transport of proteins across the Golgi stack of mammalian and plant cells is the subject of intense debate, with two models, cisternal progression and inter-cisternal exchange, emerging as major contenders. A…

Subcellular Processes · Quantitative Biology 2014-03-05 Serge Dmitrieff , Madan Rao , Pierre Sens

Ion transport through charged nanopores is commonly interpreted in terms of electrical double layer structure, leading to the expectation of cation-selective conduction in negatively charged pores. This picture can break down for…

Statistical Mechanics · Physics 2026-04-29 Salman Shabbir , Dezső Boda , Zoltán Ható

After a brief review of the protein folding quantum theory and a short discussion on its experimental evidences the mechanism of glucose transport across membrane is studied from the point of quantum conformational transition. The…

Biomolecules · Quantitative Biology 2014-11-27 Liaofu Luo

The dynamics of polymer translocation through a pore has been the subject of recent theoretical and experimental works. We have considered theoretical estimates and performed computer simulations to understand the mechanism of DNA uptake…

Soft Condensed Matter · Physics 2009-11-07 Zeno Farkas , Imre Derenyi , Tamas Vicsek

We show that transport in the presence of entropic barriers exhibits peculiar characteristics which makes it distinctly different from that occurring through energy barriers. The constrained dynamics yields a scaling regime for the particle…

Statistical Mechanics · Physics 2009-11-11 D. Reguera , G. Schmid , P. S. Burada , J. M. Rubí , P. Hänggi

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

Biological Physics · Physics 2017-03-30 Isabella R. Graf , Erwin Frey

Various molecules exclusively accumulate at the front or back of migrating eukaryotic cells in response to a shallow gradient of extracellular signals. Directional sensing and signal amplification highlight the essential properties in the…

Cell Behavior · Quantitative Biology 2015-06-26 Mikiya Otsuji , Shuji Ishihara , Carl Co , Kozo Kaibuchi , Atsushi Mochizuki , Shinya Kuroda

Molecular motor proteins serve as an essential component of intracellular transport by generating forces to haul cargoes along cytoskeletal filaments. Two species of motors that are directed oppositely (e.g. kinesin, dynein) can be attached…

Subcellular Processes · Quantitative Biology 2017-05-10 Christopher E. Miles , James P. Keener

The secretion of vesicles for intracellular transport often rely on the aggregation of specialized membrane-bound proteins into a coat able to curve cell membranes. The nucleation and growth of a protein coat is a kinetic process that…

Subcellular Processes · Quantitative Biology 2009-11-13 Lionel Foret , Pierre Sens

The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular…

Statistical Mechanics · Physics 2015-05-13 C. Loverdo , O. Benichou , M. Moreau , R. Voituriez

Many biological and artificial transport channels function without direct input of metabolic energy during a transport event and without structural rearrangements involving transitions from a 'closed' to an 'open' state. Nevertheless, such…

Subcellular Processes · Quantitative Biology 2009-11-13 Anton Zilman

Gene delivery of nucleic acid to the cell nucleus is a fundamental step in gene therapy. In this review of modeling drug and gene delivery, we focus on the particular stage of plasmid DNA or virus cytoplasmic trafficking. A challenging…

Subcellular Processes · Quantitative Biology 2011-09-08 Carlo Amoruso , Thibault Lagache , David Holcman

Cells are complex structures which require considerable amounts of organization via transport of large intracellular cargo. While passive diffusion is often sufficiently fast for the transport of smaller cargo, active transport is necessary…

Biomolecules · Quantitative Biology 2018-08-29 Robert Blackwell , David Jung , Mona Bukenberger , Ana-Sunčana Smith

Polymer-coated pores play a crucial role in nucleo-cytoplasmic transport and in a number of biomimetic and nanotechnological applications. Here we present Monte Carlo and Density Functional Theory approaches to identify different collective…

Soft Condensed Matter · Physics 2015-05-30 Dino Osmanovic , Joe Bailey , Anthony H. Harker , Ariberto Fassati , Bart W. Hoogenboom , Ian J. Ford

We present an efficient and robust numerical model for simulation of electrokinetic phenomena in porous networks over a wide range of applications including energy conversion, desalination, and lab-on-a-chip systems. Coupling between fluid…

Fluid Dynamics · Physics 2016-10-04 Shima Alizadeh , Ali Mani

While ubiquitous, energy redistribution remains a poorly understood facet of the nonequilibrium thermodynamics of biomolecules. At the molecular level, finite-size effects, pronounced nonlinearities, and ballistic processes produce behavior…

Biological Physics · Physics 2019-11-15 Justin E. Elenewski , Kirill A. Velizhanin , Michael Zwolak

We theoretically investigate the flow of the atomic excitations in a driven chiral-coupled atomic chain with nonreciprocal decay channels. This one-dimensional system allows infinite-range dipole-dipole interaction, and enables directional…

Quantum Physics · Physics 2019-03-06 H. H. Jen