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Super-resolution microscopy has revolutionized optical fluorescence imaging by improving 3D resolution by 1-2 orders of magnitude. While different methods can successfully increase the resolution, all methods share significant differences…

Biological Physics · Physics 2015-01-26 Thomas Pengo , Nicolas Olivier , Suliana Manley

Spontaneous downconversion is a versatile source for correlated biphotons that has been employed in many quantum sensing and imaging experiments. Spatially-resolved photon-counting detectors allow to access a large number of modes, posing…

Instrumentation and Detectors · Physics 2019-11-26 Ermes Toninelli , Paul-Antoine Moreau , Thomas Gregory , Miles J. Padgett

Scale-invariance, good localization and robustness to noise and distortions are the main properties that a local feature detector should possess. Most existing local feature detectors find excessive unstable feature points that increase the…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Morteza Ghahremani , Yonghuai Liu , Bernard Tiddeman

Extended derivations regarding the cumulant-based formulation of higher-order fluorescence correlation spectroscopy (FCS) are presented. First, we review multivariate cumulants and their relation to photon counting distributions in single…

Chemical Physics · Physics 2018-10-16 Farshad Abdollah-Nia

Proton-proton correlations and correlations of p-alpha, d-alpha, and t-alpha from spectator decays following Au + Au collisions at 1000 AMeV have been measured with an highly efficient detector hodoscope. The constructed correlation…

Nuclear Experiment · Physics 2019-08-14 C. Schwarz

We propose an unfolded accelerated projected-gradient descent procedure to estimate model and algorithmic parameters for image super-resolution and molecule localization problems in image microscopy. The variational lower-level constraint…

Numerical Analysis · Mathematics 2024-03-27 Silvia Bonettini , Luca Calatroni , Danilo Pezzi , Marco Prato

Classification of proteins based on their structure provides a valuable resource for studying protein structure, function and evolutionary relationships. With the rapidly increasing number of known protein structures, manual and…

Computational Engineering, Finance, and Science · Computer Science 2009-07-14 Oktie Hassanzadeh

Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors". The method applies spectral analysis to a matrix obtained by combining…

Biomolecules · Quantitative Biology 2015-06-19 Tiberiu Tesileanu , Lucy J. Colwell , Stanislas Leibler

Atomic packing is an important metric for characterizing protein structures, as it significantly influences various features including the stability, the rate of evolution and the functional roles of proteins. Packing in protein structures…

Biomolecules · Quantitative Biology 2025-05-27 Sotirios Touliopoulos , Nicholas M. Glykos

In single-molecule super-resolution microscopy, engineered point-spread functions (PSFs) are designed to efficiently encode new molecular properties, such as 3D orientation, into complex spatial features captured by a camera. To fully…

Image and Video Processing · Electrical Eng. & Systems 2019-07-16 Hesam Mazidi , Eshan S. King , Oumeng Zhang , Arye Nehorai , Matthew D. Lew

We show that spatial variation and correlation of superconductivity fluctuations in a two-band model are scaled by two characteristic lengths. This results in substantially more complicated picture compared to one-band systems. In…

Superconductivity · Physics 2012-11-26 T. Örd , A. Vargunin , K. Rägo

The absence of self averaging in mesoscopic systems is a consequence of long-range intensity correlation. Microwave measurements suggest and diagrammatic calculations confirm that the correlation function of the normalized intensity with…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 P. Sebbah , B. Hu , A. Z. Genack , R. Pnini , B. Shapiro

Single molecule localization microscopy (SMLM) permits the visualization of cellular structures an order of magnitude smaller than the diffraction limit of visible light, and an accurate, objective evaluation of the resolution of an SMLM…

Determining the spectral density of a molecular system immersed in a proteomic scaffold and in contact to a solvent is a fundamental challenge in the coarse-grained description of, e.g., electron and energy transfer dynamics. Once the…

Quantum Physics · Physics 2014-11-04 Leonardo A. Pachon , Paul Brumer

We study a large data set of protein structure ensembles of very diverse sizes determined by nuclear magnetic resonance. By examining the distance-dependent correlations in the displacement of residues pairs and conducting finite size…

Biological Physics · Physics 2017-03-01 Qian-Yuan Tang , Yang-Yang Zhang , Jun Wang , Wei Wang , Dante R. Chialvo

Deconvolution of the telescope Point Spread Function (PSF) is necessary for even moderate dynamic range imaging with interferometric telescopes. The process of deconvolution can be treated as a search for a model image such that the…

Astrophysics · Physics 2009-11-10 S. Bhatnagar , T. J. Cornwell

Despite the recognized importance of the multi-scale spatio-temporal organization of proteins, most computational tools can only access a limited spectrum of time and spatial scales, thereby ignoring the effects on protein behavior of the…

Biomolecules · Quantitative Biology 2011-09-21 Antoine Delmotte , Edward W Tate , Sophia N Yaliraki , Mauricio Barahona

Confocal microscopy of colloids combined with digital image processing has become a powerful tool in soft matter physics and materials science. Together, these techniques enable locating and tracking of more than half a million individual…

Soft Condensed Matter · Physics 2016-05-10 Katharine E. Jensen , Nobutomo Nakamura

We develop a coagulation-fragmentation model to study a system composed of a small number of stochastic objects moving in a confined domain, that can aggregate upon binding to form local clusters of arbitrary sizes. A cluster can also…

Subcellular Processes · Quantitative Biology 2012-01-19 Nathanael Hoze , David Holcman

High-contrast imaging of exoplanets hinges on powerful post-processing methods to denoise the data and separate the signal of a companion from its host star, which is typically orders of magnitude brighter. Existing post-processing…

Instrumentation and Methods for Astrophysics · Physics 2022-10-05 Timothy D. Gebhard , Markus J. Bonse , Sascha P. Quanz , Bernhard Schölkopf
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