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Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

We report a detailed study of neuromorphic switching behaviour in inherently complex percolating networks of self-assembled metal nanoparticles. We show that variation of the strength and duration of the electric field applied to this…

Disordered Systems and Neural Networks · Physics 2019-03-06 S. K. Bose , S. Shirai , J. B. Mallinson , S. A. Brown

Competition between synapses arises in some forms of correlation-based plasticity. Here we propose a game theory-inspired model of synaptic interactions whose dynamics is driven by competition between synapses in their weak and strong…

Disordered Systems and Neural Networks · Physics 2011-10-19 Ajaz Ahmad Bhat , Gaurang Mahajan , Anita Mehta

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

Neurons and Cognition · Quantitative Biology 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. Only recently has this most staggering example of emergent process in the natural world, began to be studied.…

Condensed Matter · Physics 2007-05-23 Ronen Segev , Eshel Ben-Jacob

We report the first results of simulating the coupling of neuronal, astrocyte, and cerebrovascular activity. It is suggested that the dynamics of the system is different from systems that only include neurons. In the neuron-vascular…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Xi Shen , Philippe De Wilde

Correlating neural communication in brain networks with behavior and cognition can provide fundamental insights into the functionality of both healthy and diseased brains. We demonstrate how communication in the brain can be estimated from…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Felix Schwock , Julien Bloch , Les Atlas , Shima Abadi , Azadeh Yazdan-Shahmorad

Neurons regulate the distribution of signaling components across an extended tree-like cellular structure using both local and global feedback control. This is hypothesized to allow homeostatic control of the electrical activity of a neuron…

Adaptation and Self-Organizing Systems · Physics 2021-04-27 Saeed Aljaberi , Adriano Bellotti , Timothy O'Leary , Fulvio Forni

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

Conceptual and mathematical models of neurons have lagged behind empirical understanding for decades. Here we extend previous work in modeling biological systems with fully scale-independent quantum information-theoretic tools to develop a…

Neurons and Cognition · Quantitative Biology 2022-07-21 Chris Fields , James F. Glazebrook , Michael Levin

Biological nervous systems consist of networks of diverse, sophisticated information processors in the form of neurons of different classes. In most artificial neural networks (ANNs), neural computation is abstracted to an activation…

Neural and Evolutionary Computing · Computer Science 2023-06-12 Joachim Winther Pedersen , Sebastian Risi

Neural connectivity at the cellular and mesoscopic level appears very specific and is presumed to arise from highly specific developmental mechanisms. However, there are general shared features of connectivity in systems as different as the…

Neurons and Cognition · Quantitative Biology 2009-12-06 Marcus Kaiser , Claus C. Hilgetag , Arjen van Ooyen

We study the evolution of a random weighted network with complex nonlinear dynamics at each node, whose activity may cease as a result of interactions with other nodes. Starting from a knowledge of the micro-level behaviour at each node, we…

Statistical Mechanics · Physics 2007-05-23 Sitabhra Sinha , Sudeshna Sinha

A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Quantitative Methods · Quantitative Biology 2025-08-14 Nashira Baena , Mariana da Silva , Irina Grigorescu , Aakash Saboo , Saga Masui , Jaques-Donald Tournier , Emma C. Robinson

An artificial neuron is modelled as a weighted summation followed by an activation function which determines its output. A wide variety of activation functions such as rectified linear units (ReLU), leaky-ReLU, Swish, MISH, etc. have been…

Machine Learning · Computer Science 2019-12-30 Fayyaz ul Amir Afsar Minhas , Amina Asif

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

Neurons and Cognition · Quantitative Biology 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

Network architecture forms a critical constraint on neuronal function. Here we examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal…

Neurons and Cognition · Quantitative Biology 2016-08-02 Laura Wiles , Shi Gu , Fabio Pasqualetti , Danielle S. Bassett , David F. Meaney

Recent experimental studies of living neural networks reveal that their global activation induced by electrical stimulation can be explained using the concept of bootstrap percolation on a directed random network. The experiment consists in…

Probability · Mathematics 2015-05-14 Hamed Amini