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Collective cell migration in response to a chemical cue occurs in many biological processes such as morphogenesis and cancer metastasis. Clusters of migratory cells in these systems are capable of responding to gradients of less than 1%…

Biological Physics · Physics 2016-08-24 Julien Varennes , Bumsoo Han , Andrew Mugler

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

Statistical Mechanics · Physics 2009-09-01 Pierre-Henri Chavanis

Chemotaxis, the directional locomotion of cells towards a source of a chemical gradient, is an integral part of many biological processes - for example, bacteria motion, single-cell or multicellular organisms development, immune response,…

Analysis of PDEs · Mathematics 2021-03-29 Yishu Gong , Alexander Kiselev

Microswimmers display an intriguing ability to navigate through fluids with spatially varying viscosity, a behavior known as viscotaxis, which plays a crucial role in guiding their motion. In this study, we reveal that the orientation…

Fluid Dynamics · Physics 2025-06-25 Takuya Kobayashi , Ryoichi Yamamoto

Chemotaxis enables marine bacteria to increase encounters with phytoplankton cells by reducing their search times, provided that bacteria detect noisy chemical gradients around phytoplankton. Gradient detection depends on bacterial…

Biological Physics · Physics 2025-01-14 Riccardo Foffi , Douglas R. Brumley , François Peaudecerf , Roman Stocker , Jonasz Słomka

Swimming microorganisms often have to propel in complex, non-Newtonian fluids. We carry out experiments with self-propelling helical swimmers driven by an externally rotating magnetic field in shear-thinning, inelastic fluids. Similarly to…

Fluid Dynamics · Physics 2017-03-08 Saul Gomez , Francisco Godinez , Eric Lauga , Roberto Zenit

Many chemotactic bacteria inhabit environments in which chemicals appear as localized pulses and evolve by processes such as diffusion and mixing. We show that, in such environments, physical limits on the accuracy of temporal gradient…

Biological Physics · Physics 2016-01-19 Andrew M. Hein , Douglas R. Brumley , Francesco Carrara , Roman Stocker , Simon A. Levin

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

Cell Behavior · Quantitative Biology 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

Cell Behavior · Quantitative Biology 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Kinetic-transport equations that take into account the intra-cellular pathways are now considered as the correct description of bacterial chemotaxis by run and tumble. Recent mathematical studies have shown their interest and their…

Analysis of PDEs · Mathematics 2018-06-13 Benoît Perthame , Weiran Sun , Min Tang

Swimming bacteria detect chemical gradients by performing temporal comparisons of recent measurements of chemical concentration. These comparisons are described quantitatively by the chemotactic response function, which we expect to…

Cell Behavior · Quantitative Biology 2009-11-13 Damon A. Clark , Lars C. Grant

A common feature of biological self-organization is how active agents communicate with each other or their environment via chemical signaling. Such communications, mediated by self-generated chemical gradients, have consequences for both…

Soft Condensed Matter · Physics 2023-11-07 Babak Vajdi Hokmabad , Suropriya Saha , Jaime Agudo-Canalejo , Ramin Golestanian , Corinna C. Maass

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

Analysis of PDEs · Mathematics 2026-03-10 Valeria Cuentas , Elio Espejo

Many eukaryotic cells chemotax, sensing and following chemical gradients. However, experiments have shown that even under conditions when single cells cannot chemotax, small clusters may still follow a gradient. This behavior has been…

Biological Physics · Physics 2023-07-19 Brian A. Camley , Juliane Zimmermann , Herbert Levine , Wouter-Jan Rappel

Many microorganisms take a chiral path while swimming in an ambient uid. In this paper, we study the combined behavior of two chiral swimmers using the well-known squirmer model taking into account chiral asymmetries. In contrast to the…

Soft Condensed Matter · Physics 2022-02-23 P. S. Burada , R. Maity , F. Jülicher

Biological microswimmers are known to navigate upstream of an external flow (positive rheotaxis) in trajectories ranging from linear, spiral to oscillatory. Such rheotaxis stems from the interplay between the motion and complex shapes of…

Soft Condensed Matter · Physics 2022-05-27 Ranabir Dey , Carola M. Buness , Babak Vajdi Hokmabad , Chenyu Jin , Corinna C. Maass

We discuss recent progress in the theoretical description of chemotaxis by coupling the diffusion equation of a chemical species to equations describing the motion of sensing microorganisms. In particular, we discuss models for…

Soft Condensed Matter · Physics 2019-02-05 B. Liebchen , H. Löwen

We report the first experimental realization of a chiral artificial microswimmer exhibiting the helical motion. We found that a cholesteric liquid crystal droplet with a helical director field swims in a helical path driven by the Marangoni…

Soft Condensed Matter · Physics 2018-01-17 Takaki Yamamoto , Masaki Sano

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

Soft Condensed Matter · Physics 2023-05-24 Hugues Meyer , Heiko Rieger