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The stability of cortical function depends critically on proper regulation. Under conditions of migraine and stroke a breakdown of transmembrane chemical gradients can spread through cortical tissue. A concomitant component of this emergent…

Pattern Formation and Solitons · Physics 2009-11-13 Markus A. Dahlem , Felix M. Schneider , Eckehard Schoell

Spreading depression (SD) is a wave phenomenon in gray matter tissue. Locally, it is characterized by massive re-distribution of ions across cell membranes. As a consequence, there is a sustained membrane depolarization and tissue…

Neurons and Cognition · Quantitative Biology 2014-11-18 Bas-Jan Zandt , Bennie ten Haken , Michel J. A. M. van Putten , Markus A. Dahlem

Cortical spreading depression and spreading depolarization (CSD) are waves of neuronal depolarization that spread across the cortex, leading to a temporary saturation of brain activity. They are associated to various brain disorders such as…

Dynamical Systems · Mathematics 2023-06-16 David Reyner-Parra , Carles Bonet , Teresa M. Seara , Gemma Huguet

Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…

Transient dynamics is pervasive in the human brain and poses challenging problems both in mathematical tractability and clinical observability. We investigate statistical properties of transient cortical wave patterns with characteristic…

Pattern Formation and Solitons · Physics 2012-11-06 Markus A Dahlem , Thomas M Isele

Neurons are often connected, spatially and temporally, in phenomenal ways that promote wave propagation. Therefore, it is essential to analyze the emergent spatiotemporal patterns to understand the working mechanism of brain activity,…

Pattern Formation and Solitons · Physics 2021-10-04 Argha Mondal , Chittaranjan Hens , Arnab Mondal , Chris G. Antonopoulos

Excitable waves arise in many spatially-extended systems of either biological, chemical, or physical nature due to the interplay between local reaction and diffusion processes. Here we demonstrate that similar phenomena are encoded in the…

Pattern Formation and Solitons · Physics 2019-05-08 Francesco Marino , Giovanni Giacomelli

We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines,…

Tissues and Organs · Quantitative Biology 2026-01-07 Romina Travaglini

We systematically investigate rogue wave's spatial-temporal pattern in $N$ $(N\geq2)$-component coupled defocusing nonlinear Schr\"{o}dinger equations. The fundamental rogue wave solutions are given in a unified form for both focusing and…

Pattern Formation and Solitons · Physics 2022-12-16 Yan-Hong Qin , Liming Ling , Li-Chen Zhao

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira

We present a detailed discussion of scalar wave propagation and light intensity transport in three dimensional random dielectric media with optical gain. The intrinsic length and time scales of such amplifying systems are studied and…

Disordered Systems and Neural Networks · Physics 2015-05-28 R. Frank , A. Lubatsch

Prevention of secondary brain injury is a core aim of neurocritical care, with Spreading Depolarizations (SDs) recognized as a significant independent cause. SDs are typically monitored through invasive, high-frequency electrocorticography…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Jeanne Boyer-Chammard , Yinzhe Wu , Chenyu Zhang , Sharon Jewell , Anthony Strong , Guang Yang , Martyn Boutelle

Spiral waves are self-repeating waves that can form in excitable media, propagating outward from their center in a spiral pattern. Spiral waves have been observed in different natural phenomena and have been linked to medical conditions…

Cellular Automata and Lattice Gases · Physics 2020-08-11 Vincent Vangelista , Karl Amjad-Ali , Minhyeok Kwon , Paulo H. Acioli

We consider a spatially distributed population dynamics model with excitable predator-prey dynamics, where species propagate in space due to their taxis with respect to each other's gradient in addition to, or instead of, their diffusive…

Pattern Formation and Solitons · Physics 2009-11-10 V. N. Biktashev , J. Brindley , A. V. Holden , M. A. Tsyganov

We identify a new type of pattern formation in spatially distributed active systems. We simulate one-dimensional two-component systems with predator-prey local interaction and pursuit-evasion taxis between the components. In a sufficiently…

Pattern Formation and Solitons · Physics 2013-05-29 V. N. Biktashev , M. A. Tsyganov

To gain insight into the neural events responsible for visual perception of static and dynamic optical patterns, we study how neural activation spreads in arrays of inhibition-stabilized neural networks with nearest-neighbor coupling. The…

Neurons and Cognition · Quantitative Biology 2016-09-02 Sergey Savel'ev , Sergei Gepshtein

The present work explores the potential for observing multiple reentrant localization behavior in a double-stranded helical (DSH) system, extending beyond the conventional nearest-neighbor hopping interaction. The DSH system is considered…

Mesoscale and Nanoscale Physics · Physics 2023-07-11 Sudin Ganguly , Suparna Sarkar , Kallol Mondal , Santanu K. Maiti

The modelling of linear and nonlinear reaction-subdiffusion processes is more subtle than normal diffusion and causes different phenomena. The resulting equations feature a spatial Laplacian with a temporal memory term through a time…

Analysis of PDEs · Mathematics 2021-08-24 Jichen Yang , Jens D. M. Rademacher

Inspired by the operation of biological brains, Spiking Neural Networks (SNNs) have the unique ability to detect information encoded in spatio-temporal patterns of spiking signals. Examples of data types requiring spatio-temporal processing…

Neural and Evolutionary Computing · Computer Science 2021-04-27 Nicolas Skatchkovsky , Hyeryung Jang , Osvaldo Simeone

Spatio-temporal extensions of familiar compartment models for disease transmission incorporating diffusive behavior, or interactions between individuals at separate locations, are explored. The models considered have the character of…

Biological Physics · Physics 2022-06-28 Joseph Rudnick , David Jasnow , Jorge Vinals
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