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Related papers: CLeFAPS: Fast Flexible Alignment of Protein Struct…

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Federated learning enables training on a massive number of edge devices. To improve flexibility and scalability, we propose a new asynchronous federated optimization algorithm. We prove that the proposed approach has near-linear convergence…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-08 Cong Xie , Sanmi Koyejo , Indranil Gupta

While machine learning models have achieved unprecedented success in real-world applications, they might make biased/unfair decisions for specific demographic groups and hence result in discriminative outcomes. Although research efforts…

Machine Learning · Computer Science 2022-12-08 Yuying Zhao , Yu Wang , Tyler Derr

Semi-dense feature matching methods have shown strong performance in challenging scenarios. However, the existing pipeline relies on a global search across the entire feature map to establish coarse matches, limiting further improvements in…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Peiqi Chen , Lei Yu , Yi Wan , Yingying Pei , Xinyi Liu , Yongxiang Yao , Yingying Zhang , Lixiang Ru , Liheng Zhong , Jingdong Chen , Ming Yang , Yongjun Zhang

De novo prediction of protein structures, the prediction of structures from amino-acid sequences which are not similar to those of hitherto resolved structures, has been one of the major challenges in molecular biophysics. In this paper, we…

Biomolecules · Quantitative Biology 2008-02-22 Takeshi N. Sasaki , Hikmet Cetin , Masaki Sasai

Along with the flourish of the information age, massive amounts of data are generated day by day. Due to the large-scale and high-dimensional characteristics of these data, it is often difficult to achieve better decision-making in…

Machine Learning · Computer Science 2023-04-04 Peican Zhu , Xin Hou , Keke Tang , Zhen Wang , Feiping Nie

Accurately segmenting structural cracks at the pixel level remains a major hurdle, as existing methods fail to integrate local textures with pixel dependencies, often leading to fragmented and incomplete predictions. Moreover, their high…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Hui Liu , Chen Jia , Fan Shi , Xu Cheng , Mianzhao Wang , Shengyong Chen , Yang Lv

Counterfactual explanations (CFE) are being widely used to explain algorithmic decisions, especially in consequential decision-making contexts (e.g., loan approval or pretrial bail). In this context, CFEs aim to provide individuals affected…

Machine Learning · Computer Science 2021-02-09 Kiarash Mohammadi , Amir-Hossein Karimi , Gilles Barthe , Isabel Valera

Side chain flexibility is an important factor in ligand binding. In order to determine the extent to which side chain flexibility is involved in ligand binding, a knowledge-based approach was taken. A database composed of examples of…

Biomolecules · Quantitative Biology 2013-01-22 Rafael Najmanovich

We introduce a new multi-dimensional nonlinear embedding -- Piecewise Flat Embedding (PFE) -- for image segmentation. Based on the theory of sparse signal recovery, piecewise flat embedding with diverse channels attempts to recover a…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chaowei Fang , Zicheng Liao , Yizhou Yu

Despite the widespread application of latent factor analysis, existing methods suffer from the following weaknesses: requiring the number of factors to be known, lack of theoretical guarantees for learning the model structure, and…

Methodology · Statistics 2023-06-06 Dale S. Kim , Qing Zhou

This work presents CLIPDraw, an algorithm that synthesizes novel drawings based on natural language input. CLIPDraw does not require any training; rather a pre-trained CLIP language-image encoder is used as a metric for maximizing…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Kevin Frans , L. B. Soros , Olaf Witkowski

Multifractal analysis (MFA) is a useful tool to systematically describe the spatial heterogeneity of both theoretical and experimental fractal patterns. One of the widely used methods for fractal analysis is box-covering. It is known to be…

Physics and Society · Physics 2021-04-14 Yuemin Ding , Jin-Long Liu , Xiaohui Li , Yu-Chu Tian , Zu-Guo Yu

The scientific computation of large deformations in elastic-plastic solids is crucial in various manufacturing applications. Traditional numerical methods exhibit several inherent limitations, prompting Deep Learning (DL) as a promising…

Artificial Intelligence · Computer Science 2026-01-16 Jianheng Tang , Shilong Tao , Zhe Feng , Haonan Sun , Menglu Wang , Zhanxing Zhu , Yunhuai Liu

Antifreeze proteins (AFPs) are the sub-set of ice binding proteins indispensable for the species living in extreme cold weather. These proteins bind to the ice crystals, hindering their growth into large ice lattice that could cause…

Quantitative Methods · Quantitative Biology 2019-10-16 Muhammad Usman , Jeong A Lee

To accurately compute data-based prediction of Hamiltonian systems, especially the long-term evolution of such systems, it is essential to utilize methods that preserve the structure of the equations over time. We consider a case that is…

Machine Learning · Computer Science 2024-08-30 Christopher Eldred , François Gay-Balmaz , Vakhtang Putkaradze

Modeling fine-grained speaking styles remains challenging for language-speech representation pre-training, as existing speech-text models are typically trained with coarse captions or task-specific supervision, and scalable fine-grained…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-21 Yifan Yang , Bing Han , Hui Wang , Wei Wang , Ziyang Ma , Long Zhou , Zengrui Jin , Guanrou Yang , Tianrui Wang , Xu Tan , Xie Chen

Planning is a crucial task for agents in task oriented dialogs (TODs). Human agents typically resolve user issues by following predefined workflows, decomposing workflow steps into actionable items, and performing actions by executing APIs…

Computation and Language · Computer Science 2024-06-06 Shamik Roy , Sailik Sengupta , Daniele Bonadiman , Saab Mansour , Arshit Gupta

Benefiting from the inductive biases learned from large-scale datasets, open-vocabulary semantic segmentation (OVSS) leverages the power of vision-language models, such as CLIP, to achieve remarkable progress without requiring task-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Qiming Huang , Hao Ai , Jianbo Jiao

The recent breakthrough of AlphaFold3 in modeling complex biomolecular interactions, including those between proteins and ligands, nucleotides, or metal ions, creates new opportunities for protein design. In so-called inverse protein…

Biomolecules · Quantitative Biology 2025-07-22 Kai Yi , Kiarash Jamali , Sjors H. W. Scheres

Most widely used ligand docking methods assume a rigid protein structure. This leads to problems when the structure of the target protein deforms upon ligand binding. In particular, the ligand's true binding pose is often scored very…

Biomolecules · Quantitative Biology 2023-03-22 Patricia Suriana , Joseph M. Paggi , Ron O. Dror