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We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

Trans-membrane gradients and fluxes of cations (H+, Na+, K+, etc.) were deemed to be the rationale of electrical activities of aerobic cells/organelles, as per classical perceptions. Murburn concept (an umbrella of theorization based in…

Neurons and Cognition · Quantitative Biology 2026-04-29 Kelath Murali Manoj , Nagamani Sukumar

Active sensing is traditionally defined as the expenditure of energy, typically in the form of movement, for obtaining information. Here, we propose that the combination of reliance on adaptive sensors, the linkage between movement and…

Neurons and Cognition · Quantitative Biology 2026-05-25 Andrew Lamperski , Debojyoti Biswas , Eric S. Fortune , John Guckenheimer , Kathleen Hoffman , Noah J. Cowan

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the…

Neurons and Cognition · Quantitative Biology 2020-09-23 Danko D. Georgiev , Stefan K. Kolev , Eliahu Cohen , James F. Glazebrook

Neurons subject to a common non-stationary input may exhibit a correlated firing behavior. Correlations in the statistics of neural spike trains also arise as the effect of interaction between neurons. Here we show that these two situations…

Quantitative Methods · Quantitative Biology 2021-04-13 Joanna Tyrcha , Yasser Roudi , Matteo Marsili , John Hertz

Neural networks are powerful functions with widespread use, but the theoretical behaviour of these functions is not fully understood. Creating deep neural networks by stacking many layers has achieved exceptional performance in many…

Machine Learning · Computer Science 2024-08-16 Cameron Jakub , Mihai Nica

We propose two new criteria to understand the advantage of deepening neural networks. It is important to know the expressivity of functions computable by deep neural networks in order to understand the advantage of deepening neural…

Machine Learning · Computer Science 2024-03-06 Yasushi Esaki , Yuta Nakahara , Toshiyasu Matsushima

While spiking neural networks (SNNs) provide a biologically inspired and energy-efficient computational framework, their robustness and the dynamic advantages inherent to biological neurons remain significantly underutilized owing to…

Neural and Evolutionary Computing · Computer Science 2025-09-04 Qianyi Bai , Haiteng Wang , Qiang Yu

Efficient pattern separation in dentate gyrus plays an important role in storing information in the hippocampus. Current knowledge of the structure and function of the hippocampus, entorhinal cortex and dentate gyrus, in pattern separation…

Neurons and Cognition · Quantitative Biology 2018-08-02 Faramarz Faghihi , Homa Samani , Ahmed A. Moustafa

Spontaneous brain activity in the absence of external stimuli is not random but contains complex dynamical structures such as neuronal avalanches with power-law duration and size distributions. These experimental observations have been…

Biological Physics · Physics 2024-12-04 Lik-Chun Chan , Tsz-Fung Kok , Emily S. C. Ching

Recent studies of cortical neurons driven by fluctuating currents revealed cutoff frequencies for action potential encoding of several hundred Hz. Theoretical studies of biophysical neuron models have predicted a much lower cutoff frequency…

Neurons and Cognition · Quantitative Biology 2015-05-27 Wei Wei , Fred Wolf

Introduced is a methodology for adapting the topology of dense neural networks, enabled by isotropic activation functions. Achieved through prescribed reparameterisation symmetries and singular-value decomposition of affine maps, this…

Neural and Evolutionary Computing · Computer Science 2026-05-08 George Bird

Laboratory-grown, engineered living neuronal networks in vitro have emerged in the last years as an experimental technique to understand the collective behavior of neuronal assemblies in relation to their underlying connectivity. An…

Neurons and Cognition · Quantitative Biology 2025-01-09 Akke Mats Houben , Jordi Garcia-Ojalvo , Jordi Soriano

To understand how neurons and nervous systems first evolved, we need an account of the origins of neural elongations: Why did neural elongations (axons and dendrites) first originate, such that they could become the central component of…

Neurons and Cognition · Quantitative Biology 2017-10-31 Oltman O. de Wiljes , Ronald A. J. van Elburg , Fred A. Keijzer

Recent experimental results based on multi-electrode and imaging techniques have reinvigorated the idea that large neural networks operate near a critical point, between order and disorder. However, evidence for criticality has relied on…

Neurons and Cognition · Quantitative Biology 2015-03-05 Thierry Mora , Stéphane Deny , Olivier Marre

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

Neurons and Cognition · Quantitative Biology 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

We consider neural networks with rational activation functions. The choice of the nonlinear activation function in deep learning architectures is crucial and heavily impacts the performance of a neural network. We establish optimal bounds…

Neural and Evolutionary Computing · Computer Science 2020-10-01 Nicolas Boullé , Yuji Nakatsukasa , Alex Townsend

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

We study the response properties of d-dimensional hypercubic excitable networks to a stochastic stimulus. Each site, modelled either by a three-state stochastic susceptible-infected-recovered-susceptible system or by the probabilistic…

Neurons and Cognition · Quantitative Biology 2008-02-13 Vladimir R. V. Assis , Mauro Copelli
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