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Ab initio molecular dynamics simulations of liquid water under equilibrium ambient conditions, together with a novel energy decomposition analysis, have recently shown that a substantial fraction of water molecules exhibit a significant…

Disordered Systems and Neural Networks · Physics 2020-06-24 Hossam Elgabarty , Thomas D. Kühne

Thermodynamic properties of the particles interacting through smooth version of Stell-Hemmer interaction were studied using Wertheim's thermodynamic perturbation theory. The temperature dependence of molar volume, heat capacity, isothermal…

Soft Condensed Matter · Physics 2013-12-18 T. Urbic

Molecular dynamics simulations of SPC/E water confined in a Silica pore are presented. The simulations have been performed at different hydration levels and temperatures to study the single-particle dynamics. Due to the confinement and to…

Soft Condensed Matter · Physics 2017-08-23 Paola Gallo

Normal mode analysis is a widely used technique for reconstructing conformational changes of proteins from the knowledge of native structures. In this Letter, we investigate to what extent normal modes capture the salient features of the…

Statistical Mechanics · Physics 2015-05-13 Francesco Piazza , Paolo De Los Rios , Fabio Cecconi

Known physical mechanisms of temperature dependence anomalies of water properties were used to explain the regularities in temperature dependence (TDs) of dynamic, electrical and optical characteristics of biological systems. The dynamics…

Biological Physics · Physics 2023-08-09 Alexander Kholmanskiy

Water is a key ingredient for life and plays a central role as solvent in many biochemical reactions. However, the intrinsically quantum nature of the hydrogen nucleus, revealing itself in a large variety of physical manifestations,…

Extensive molecular dynamics computer simulations have been conducted for ethanol-water liquid mixtures in the water-rich side of the composition range, with 10, 20 and 30 mol % of the alcohol, at temperatures between room temperature and…

Chemical Physics · Physics 2019-06-12 Szilvia Pothoczki , László Pusztai , Imre Bakó

Water and glycerol are well-known to facilitate the structural relaxation of amorphous protein matrices. However, several studies evidenced that they may also limit fast ($\sim$ pico-nanosecond, ps-ns) and small-amplitude ($\sim$ \AA )…

Soft Condensed Matter · Physics 2017-10-03 Adrien Lerbret , Frédéric Affouard

In a recent paper [PRL 91, 138103 (2003)] a new mechanism to explain the cold denaturation of proteins, based on the loss of local low-density water structure, has been proposed. In the present paper this mechanism is tested by means of…

Other Condensed Matter · Physics 2009-11-11 Manuel I. Marques

In this study, the additional heat capacity which appear during the water dissociation of the proteins that are one of the soft materials, have been considered by the statistical mechanical methods. For this purpose, taking the electric…

Statistical Mechanics · Physics 2007-05-23 G. Oylumluoglu , F. Buyukkilic , D. Demirhan

We present a model of the dynamical transition of atomic displacements in proteins. Increased mean-square displacement at higher temperatures is caused by softening of the vibrational force constant by electrostatic and van der Waals forces…

Biological Physics · Physics 2017-08-07 Salman Seyedi , Dmitry V. Matyushov

Supercooled liquids exhibit spatial heterogeneity in the dynamics of their fluctuating atomic arrangements. The length and time scales of the heterogeneous dynamics are central to the glass transition and influence nucleation and growth of…

Materials Science · Physics 2018-05-09 Pei Zhang , Jason J. Maldonis , Ze Liu , Jan Schroers , Paul M. Voyles

We study the temperature dependence of the conductivity of the 2D electronic solid. In realistic samples, a domain structure forms in the solid and each domain randomly orients in the absence of the in-plane field. At higher temperature,…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 Shi-Jie Yang , Yue Yu

Using a combination of dielectric spectroscopy and solid-state deuteron NMR, the hydration water dynamics of connective tissue proteins is studied at sub-ambient temperatures. In this range, the water dynamics follows an Arrhenius law. A…

Soft Condensed Matter · Physics 2015-05-18 Sorin A. Lusceac , Markus Rosenstihl , Michael Vogel , Catalin Gainaru , Ariane Fillmer , Roland Böhmer

The understanding of dynamics and functioning of biological membranes and in particular of membrane embedded proteins is one of the most fundamental problems and challenges in modern biology and biophysics. In particular the impact of…

Biological Physics · Physics 2009-12-27 Maikel C. Rheinstadter

Novel physical mechanism is proposed for explanation of temperature-independent transition reactions in molecular systems. The mechanism becomes effective in the case of conformation transitions between quasi-isoenergetic molecular states.…

Statistical Mechanics · Physics 2012-11-01 V. I. Teslenko , E. G. Petrov , A. Verkhratsky , O. A. Krishtal

We investigate dynamical heterogeneities in the collective relaxation of a concentrated microgel system, for which the packing fraction can be conveniently varied by changing the temperature. The packing fraction dependent mechanical…

Soft Condensed Matter · Physics 2011-05-31 David A. Sessoms , Irmgard Bischofberger , Luca Cipelletti , Véronique Trappe

Water plays a fundamental role in protein stability. However, the effect of the properties of water on the behaviour of proteins is only partially understood. Several theories have been proposed to give insight into the mechanisms of cold…

Soft Condensed Matter · Physics 2021-03-25 Giancarlo Franzese , Joan Àguila Rojas , Valentino Bianco , Ivan Coluzza

Water is an ubiquitous liquid that has several exotic and anomalous properties. Despite its apparent simple chemical formula, its capability of forming a dynamic network of hydrogen bonds leads to a rich variety of physics. Here we study…

Soft Condensed Matter · Physics 2023-08-15 R. Vuilleumier , A. P. Seitsonen

A highly diluted aqueous solution of histamine was studied by molecular dynamics using the TIP3P and SPC/E water models. It was shown that the local structure of the solution around histamine is determined by local Coulomb interactions and…

Biomolecules · Quantitative Biology 2026-01-09 Dmytro A. Gavryushenko , N. Atamas , Oleg K. Myronenko
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