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Experiments in bulk water confirm the existence of two local arrangements of water molecules with different densities, but, because of inevitable freezing at low temperature $T$, can not ascertain whether the two arrangements separate in…

We investigate the temperature dependence of thermodynamic (density, isobaric heat capacity), dynamical (self-diffusion coefficient, shear viscosity), and dielectric properties of several water models, the commonly employed TIP3P water…

Soft Condensed Matter · Physics 2022-04-13 Tatiana I. Morozova , Nicolas A. Garcia , Jean-Louis Barrat

The mechanisms of cold- and pressure-denaturation of proteins are matter of debate and are commonly understood as due to water-mediated interactions. Here we study several cases of proteins, with or without a unique native state, with or…

Biological Physics · Physics 2026-01-13 Valentino Bianco , Giancarlo Franzese

Water is vital for life, and without it biomolecules and cells cannot maintain their structures and functions. The remarkable properties of water originate from its ability to form hydrogen-bonding networks and dynamics, which the…

Soft Condensed Matter · Physics 2023-06-01 Nguyen Q. Vinh , Luan C. Doan , Ngoc L. H. Hoang , Jiarong R. Cui , Ben Sindle

Series of molecular dynamics simulations for 2-propanol-water mixtures, as a function of temperature (between freezing and room temperature) and composition (xip= 0, 0.5, 0.1 and 0.2) have been performed for temperatures reported in the…

Chemical Physics · Physics 2019-11-06 Szilvia Pothoczki , László Pusztai , Imre Bakó

We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an "all-or-none" manner during the unfolding of the protein chain. As a consequence of…

Condensed Matter · Physics 2009-10-31 Audun Bakk , Alex Hansen , Kim Sneppen

The thermodynamics of hydration changes gradually from entropic for small solutes to enthalpic for large ones. The small-to-large crossover lengthscale of hydrophobic hydration depends on the thermodynamic conditions of the solvent such as…

Soft Condensed Matter · Physics 2015-06-15 Yuri S. Djikaev , Eli Ruckenstein

We have investigated thermodynamic and dynamic properties as well as the dielectric constant of water-metha\-nol model mixtures in the entire range of composition by using constant pressure molecular dynamics simulations at ambient…

Soft Condensed Matter · Physics 2015-12-25 E. Galicia-Andrés , H. Dominguez , L. Pusztai , O. Pizio

The interactions of a protein, its phase behavior, and ultimately, its ability to function, are all influenced by the interactions between the protein and its hydration waters. Here we study proteins with a variety of sizes, shapes,…

Chemical Physics · Physics 2018-11-08 Nicholas B. Rego , Erte Xi , Amish J. Patel

Temperature dependent hydrogen bond energetics and dynamical features, such as the diffusion coefficient and reorientational times, have been determined for ethanol-water mixtures with 10, 20 and 30 mol % of ethanol. Concerning pairwise…

Chemical Physics · Physics 2019-06-12 Szilvia Pothoczki , László Pusztai , Imre Bakó

Using modified Arrhenius approximations, the activation energies of water, alcohols, and hexane structure rearrangement reactions responsible for temperature dependences of their dynamic and dielectric characteristics were determined. The…

Chemical Physics · Physics 2021-01-19 Alexander Kholmanskiy

Dynamic structuring of water is a key player in a large class of processes underlying biochemical and technological developments today, the latter often involving electric fields. However, the anisotropic coupling between the water…

Soft Condensed Matter · Physics 2019-05-29 Andreas Baer , Zoran Miličević , David M. Smith , Ana-Sunčana Smith

Since the structural transformations observed in water-ethanol binary mixtures are apparently driven by relatively weak intermolecular forces (like hydrophobicity and hydrogen bonding) that often cooperate to form self assembled structures,…

Soft Condensed Matter · Physics 2016-05-03 Rikhia Ghosh , Biman Bagchi

We use molecular dynamics simulations to probe the rotational dynamics of the SPC/E model of water for a range of temperatures down to 200 K, 13 K above to the mode coupling temperature. We find that rotational dynamics is spatially…

Soft Condensed Matter · Physics 2015-06-25 Marco G. Mazza , Nicolas Giovambattista , Francis W. Starr , H. Eugene Stanley

Enhanced dynamical fluctuations of RNAs, facilitated by a network of water molecules with strong interactions with RNA, are suspected to be critical in their ability to respond to a variety of cellular signals. Using atomically detailed…

Biomolecules · Quantitative Biology 2015-01-15 Jeseong Yoon , Jong-Chin Lin , Changbong Hyeon , D. Thirumalai

A low-temperature dynamical transition has been reported in several proteins. We provide the first observation of a `protein-like' dynamical transition in nonbiological aqueous environments. To this aim we exploit the popular colloidal…

Four scenarios have been proposed for the low--temperature phase behavior of liquid water, each predicting different thermodynamics. The physical mechanism which leads to each is debated. Moreover, it is still unclear which of the scenarios…

Soft Condensed Matter · Physics 2009-08-27 Kevin Stokely , Marco G. Mazza , H. Eugene Stanley , Giancarlo Franzese

We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the impact of hydrodynamic interactions, whether it accelerates, retards, or has no effect on protein folding, has…

Biomolecules · Quantitative Biology 2018-03-14 Fabio C. Zegarra , Dirar Homouz , Yossi Eliaz , Andrei G. Gasic , Margaret S. Cheung

In this work, we have carried out molecular dynamics (MD) simulation techniques to study the diffusion coefficient of interlayer molecules at different temperature. Within the wider context of water dynamics in soils, and with a particular…

Soft Condensed Matter · Physics 2023-03-23 H. O. Mohammed , K. N. Nigussa

Polyamide 6,6 (PA66) is a key engineering polymer, whose unique mechanical properties arise from strong interchain hydrogen bonding. However, its hygroscopic nature makes it highly sensitive to water uptake, which markedly alters its…

Materials Science · Physics 2026-03-17 Karim Gadelrab , Armin Kech , Camilo Cruz