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Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

This article presents a mini-review about the progress in inferring monosynaptic connections from spike trains of multiple neurons over the past twenty years. First, we explain a variety of meanings of ``neuronal connectivity'' in different…

Neurons and Cognition · Quantitative Biology 2024-03-19 Ryota Kobayashi , Shigeru Shinomoto

Characterising the interactions between spiking neurons is central to our understanding of cognitive processes such as memory, perception and decision making. In this work, we consider the problem of inferring connectivity in the brain…

Applications · Statistics 2025-07-25 Carla Pinkney , Carolina Euan , Alex Gibberd

The inverse problem of statistical mechanics involves finding the minimal Hamiltonian that is consistent with some observed set of correlation functions. This problem has received renewed interest in the analysis of biological networks; in…

Neurons and Cognition · Quantitative Biology 2010-12-30 Feraz Azhar , William Bialek

Statistical similarities between neuronal spike trains could reveal significant information on complex underlying processing. In general, the similarity between synchronous spike trains is somewhat easy to identify. However, the similar…

Neurons and Cognition · Quantitative Biology 2021-03-16 Sathish Ande , Jayanth R Regatti , Neha Pandey , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

Network reliability is the probability that a dynamical system composed of discrete elements interacting on a network will be found in a configuration that satisfies a particular property. We introduce a new reliability property, Ising…

Statistical Mechanics · Physics 2016-11-23 Yihui Ren , Stephen Eubank , Madhurima Nath

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Inference and learning of graphical models are both well-studied problems in statistics and machine learning that have found many applications in science and engineering. However, exact inference is intractable in general graphical models,…

Machine Learning · Statistics 2015-02-04 Jason K. Johnson , Diane Oyen , Michael Chertkov , Praneeth Netrapalli

Neurons in the nervous system convey information to higher brain regions by the generation of spike trains. An important question in the field of computational neuroscience is how these sensory neurons encode environmental information in a…

Neurons and Cognition · Quantitative Biology 2013-09-13 Alex Susemihl , Ron Meir , Manfred Opper

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

Statistics Theory · Mathematics 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Non-equilibrium systems lack an explicit characterisation of their steady state like the Boltzmann distribution for equilibrium systems. This has drastic consequences for the inference of parameters of a model when its dynamics lacks…

Statistical Mechanics · Physics 2016-11-15 Simon L. Dettmer , H. Chau Nguyen , Johannes Berg

We study inference and reconstruction of couplings in a partially observed kinetic Ising model. With hidden spins, calculating the likelihood of a sequence of observed spin configurations requires performing a trace over the configurations…

Disordered Systems and Neural Networks · Physics 2021-04-13 Benjamin Dunn , Yasser Roudi

Neuroimaging data can be represented as networks of nodes and edges that capture the topological organization of the brain connectivity. Graph theory provides a general and powerful framework to study these networks and their structure at…

Neurons and Cognition · Quantitative Biology 2017-05-19 Cécile Bordier , Carlo Nicolini , Angelo Bifone

Maximum entropy methods, rooted in the inverse Ising/Potts problem from statistical physics, are widely used to model pairwise interactions in complex systems across disciplines such as bioinformatics and neuroscience. While successful,…

Disordered Systems and Neural Networks · Physics 2025-11-14 Aurélien Decelle , Alfonso de Jesús Navas Gómez , Beatriz Seoane

Large-scale electrophysiological recordings now allow simultaneous monitoring of thousands of neurons across multiple brain regions, revealing structured variability in neural population activity. Understanding how these collective patterns…

Neurons and Cognition · Quantitative Biology 2026-03-12 Nicolas Béreux , Giovanni Catania , Aurélien Decelle , Francesca Mignacco , Alfonso de Jesús Navas Gómez , Beatriz Seoane

In this work we explore encoding strategies learned by statistical models of sensory coding in noisy spiking networks. Early stages of sensory communication in neural systems can be viewed as encoding channels in the information-theoretic…

Neurons and Cognition · Quantitative Biology 2020-06-30 M. E. Rule , M. Sorbaro , M. H. Hennig

An introduction to the Propp-Wilson method of coupling-from-the-past for the Ising model is presented. It enables one to obtain exact samples from the equilibrium spin distribution for ferromagnetic interactions. Both uniform and random…

Materials Science · Physics 2007-05-23 Mark A. Novotny

The slowing down of Moore's law has driven the development of unconventional computing paradigms, such as specialized Ising machines tailored to solve combinatorial optimization problems. In this paper, we show a new application domain for…

Emerging Technologies · Computer Science 2024-05-31 Shaila Niazi , Navid Anjum Aadit , Masoud Mohseni , Shuvro Chowdhury , Yao Qin , Kerem Y. Camsari

Spiking activity in cortical networks is nonlinear in nature. The linear-nonlinear cascade model, some versions of which are also known as point-process generalized linear model, can efficiently capture the nonlinear dynamics exhibited by…

Neurons and Cognition · Quantitative Biology 2020-01-16 Michael Kordovan , Stefan Rotter

Neural networks excel at discovering statistical patterns in high-dimensional data sets. In practice, higher-order cumulants, which quantify the non-Gaussian correlations between three or more variables, are particularly important for the…

Machine Learning · Statistics 2024-10-16 Eszter Székely , Lorenzo Bardone , Federica Gerace , Sebastian Goldt
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