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Ising models with pairwise interactions are the least structured, or maximum-entropy, probability distributions that exactly reproduce measured pairwise correlations between spins. Here we use this equivalence to construct Ising models that…

Neurons and Cognition · Quantitative Biology 2007-05-23 Gasper Tkacik , Elad Schneidman , Michael J Berry , William Bialek

Now that spike trains from many neurons can be recorded simultaneously, there is a need for methods to decode these data to learn about the networks that these neurons are part of. One approach to this problem is to adjust the parameters of…

Quantitative Methods · Quantitative Biology 2011-06-10 John Hertz , Yasser Roudi , Joanna Tyrcha

The pairwise maximum entropy model, also known as the Ising model, has been widely used to analyze the collective activity of neurons. However, controversy persists in the literature about seemingly inconsistent findings, whose significance…

Disordered Systems and Neural Networks · Physics 2019-03-13 Cristian Zanoci , Nima Dehghani , Max Tegmark

The Ising Model has recently received much attention for the statistical description of neural spike train data. In this paper, we propose and demonstrate its use for building decoders capable of predicting, on a millisecond timescale, the…

Neurons and Cognition · Quantitative Biology 2011-05-24 Michael T. Schaub , Simon R. Schultz

Ising models with pairwise interactions are the least structured, or maximum-entropy, probability distributions that exactly reproduce measured pairwise correlations between spins. Here we use this equivalence to construct Ising models that…

Neurons and Cognition · Quantitative Biology 2009-12-31 Gasper Tkacik , Elad Schneidman , Michael J. Berry , William Bialek

During wakefulness and deep sleep brain states, cortical neural networks show a different behavior, with the second characterized by transients of high network activity. To investigate their impact on neuronal behavior, we apply a pairwise…

Neurons and Cognition · Quantitative Biology 2017-10-30 Trang-Anh Nghiem , Olivier Marre , Alain Destexhe , Ulisse Ferrari

In the brain, fine-scale correlations combine to produce macroscopic patterns of activity. However, as experiments record from larger and larger populations, we approach a fundamental bottleneck: the number of correlations one would like to…

Biological Physics · Physics 2024-02-02 Christopher W. Lynn , Qiwei Yu , Rich Pang , Stephanie E. Palmer , William Bialek

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

Several types of biological networks have recently been shown to be accurately described by a maximum entropy model with pairwise interactions, also known as the Ising model. Here we present an approach for finding the optimal mappings…

Biological Physics · Physics 2015-05-14 Jeffrey D. Fitzgerald , Tatyana O. Sharpee

Recent work has shown that probabilistic models based on pairwise interactions-in the simplest case, the Ising model-provide surprisingly accurate descriptions of experiments on real biological networks ranging from neurons to genes.…

Quantitative Methods · Quantitative Biology 2007-12-18 Tamara Broderick , Miroslav Dudik , Gasper Tkacik , Robert E. Schapire , William Bialek

Recent remarkable advances in the experimental techniques have provided a background for inferring neuronal couplings from point process data that includes a great number of neurons. Here, we propose a systematic procedure for pre- and…

Disordered Systems and Neural Networks · Physics 2020-07-08 Yu Terada , Tomoyuki Obuchi , Takuya Isomura , Yoshiyuki Kabashima

A powerful existing technique for evaluating statistical mechanical quantities in two-dimensional Ising models is based on constructing a matrix representing the nearest neighbor spin couplings and then evaluating the Pfaffian of the…

Disordered Systems and Neural Networks · Physics 2013-04-16 Creighton K. Thomas , A. Alan Middleton

The inverse Ising model is used in computational neuroscience to infer probability distributions of the synchronous activity of large neuronal populations. This method allows for finding the Boltzmann distribution with single neuron biases…

Neurons and Cognition · Quantitative Biology 2022-07-27 Geoffroy Delamare , Ulisse Ferrari

We propose a new model based on the Ising model with the aim to study synaptic plasticity phenomena in neural networks. It is today well established in biology that the synapses or connections between certain types of neurons are…

Disordered Systems and Neural Networks · Physics 2016-07-22 Eugene Pechersky , Guillem Via , Anatoly Yambartsev

Generative models offer a direct way of modeling complex data. Energy-based models attempt to encode the statistical correlations observed in the data at the level of the Boltzmann weight associated with an energy function in the form of a…

Disordered Systems and Neural Networks · Physics 2024-04-10 Aurélien Decelle , Cyril Furtlehner , Alfonso De Jesus Navas Gómez , Beatriz Seoane

Randomly coupled Ising spins constitute the classical model of collective phenomena in disordered systems, with applications covering ferromagnetism, combinatorial optimization, protein folding, stock market dynamics, and social dynamics.…

Disordered Systems and Neural Networks · Physics 2016-08-24 David Dahmen , Hannah Bos , Moritz Helias

We analyze the bootstrap approach (a dual optimization method to the variational approach) to one-dimensional spin chains, leveraging semidefinite programming to extract numerical results. We study how correlation functions in the ground…

High Energy Physics - Theory · Physics 2024-06-27 David Berenstein , George Hulsey , P. N. Thomas Lloyd

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

Neurons subject to a common non-stationary input may exhibit a correlated firing behavior. Correlations in the statistics of neural spike trains also arise as the effect of interaction between neurons. Here we show that these two situations…

Quantitative Methods · Quantitative Biology 2021-04-13 Joanna Tyrcha , Yasser Roudi , Matteo Marsili , John Hertz
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